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The map label for this gene is sigW [H]

Identifier: 13472088

GI number: 13472088

Start: 1830182

End: 1831117

Strand: Reverse

Name: sigW [H]

Synonym: mll2270

Alternate gene names: 13472088

Gene position: 1831117-1830182 (Counterclockwise)

Preceding gene: 13472089

Following gene: 13472087

Centisome position: 26.02

GC content: 64.0

Gene sequence:

>936_bases
TTGAACGGCGGGAAGCCTGGCGTGGAACGCGACCGACGCGAAGCGCTGCTTGCCCTTGCCGCCGCGCTGCGGCCGGAGCT
GCACCGCTATTGCGCGCGCCTGATGGGCTCGGTCATCGATGGCGAGGATGTGGTGCAGGACACCTTTGCCCGGGCCTTCG
TTGCGCTGGACGAACTGTGCGCGGTGCCGCAGCTCAGGCCCTGGCTGTTTCGCATTGCCCACAACAGGGCGCTGGACCTG
CTGCGCAGTCGCGCAACCCGCGTTGCGGAGCCCATCGAAGCGGCGCTTGAAATCGTCGATGACAGCAAAGCCGATGCGGT
GGAGACGCTGATGCGCAAGGAGGCAATCGAAACGGCCGTGTCGCGCTTTGCTGAGCTCCCGGTCGTCCAGCGCAGCGTCA
TCATCTTGAAAGATGTGCTCGATGAACCGCTGGCCGAGATCGCGGCCCTGCTTGGCATTTCGGTCGATGCCGTGAAAGCG
CACCTGTCTCGCGGCCGTGCCCGGCTTCGGGAGATCAACGCCAGGACCGACCCGTTTCCCGACGCGCGCATCGCTTCAGC
CAACGTGGTCCGTTACATCAATCTGTTCAACCAGCGCGACTGGGATGGCTTGCGCGCGTTGCTTGCCGAGGATGTGAGAC
TTCAGCAGTCCATGCACCCGCCACGCTCCGGTGCGGCCGATGTTGGGATGTTCTTCACGATCTATGCCAAGAGCGAGGGC
CTGTGGCTCAAGCCGGCATGGGTCGAAGGCCGCGAGGTGATCGCCGTGTTCGAACATCGGGCGGCCCCGAAGCCAACCCA
TTTCATGTGGCTGGAGTGGCGGGAAGGGCGGATCAGCTTCATCCGTGACTATCGCTATGTCGGCTATGTCGCGGACGATG
CCAGGCTGGTTCTGGCGAGCGACGTCAGGTCTTCCGGTCACGGAACCAAGCTCTGA

Upstream 100 bases:

>100_bases
ACAGGGTGGTTTCGGTGCTGGAGGACCCGCAATATGCCGAGGGTGTCGTCTTCGGCCTCAGCGGCGACGCCGGCGTTACG
ATCATGGAGGGTGCGGCGGC

Downstream 100 bases:

>100_bases
TGTCTTGGCGCTGATGTCTTGGGGCCTGCGACAACAATAAGGTTCCTGGTCGAGCAGGCCCTGGATGCCGGCTGTAGCGA
CCGCAGGGGGCCGATCGGTT

Product: RNA polymerase sigma subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNGGKPGVERDRREALLALAAALRPELHRYCARLMGSVIDGEDVVQDTFARAFVALDELCAVPQLRPWLFRIAHNRALDL
LRSRATRVAEPIEAALEIVDDSKADAVETLMRKEAIETAVSRFAELPVVQRSVIILKDVLDEPLAEIAALLGISVDAVKA
HLSRGRARLREINARTDPFPDARIASANVVRYINLFNQRDWDGLRALLAEDVRLQQSMHPPRSGAADVGMFFTIYAKSEG
LWLKPAWVEGREVIAVFEHRAAPKPTHFMWLEWREGRISFIRDYRYVGYVADDARLVLASDVRSSGHGTKL

Sequences:

>Translated_311_residues
MNGGKPGVERDRREALLALAAALRPELHRYCARLMGSVIDGEDVVQDTFARAFVALDELCAVPQLRPWLFRIAHNRALDL
LRSRATRVAEPIEAALEIVDDSKADAVETLMRKEAIETAVSRFAELPVVQRSVIILKDVLDEPLAEIAALLGISVDAVKA
HLSRGRARLREINARTDPFPDARIASANVVRYINLFNQRDWDGLRALLAEDVRLQQSMHPPRSGAADVGMFFTIYAKSEG
LWLKPAWVEGREVIAVFEHRAAPKPTHFMWLEWREGRISFIRDYRYVGYVADDARLVLASDVRSSGHGTKL
>Mature_311_residues
MNGGKPGVERDRREALLALAAALRPELHRYCARLMGSVIDGEDVVQDTFARAFVALDELCAVPQLRPWLFRIAHNRALDL
LRSRATRVAEPIEAALEIVDDSKADAVETLMRKEAIETAVSRFAELPVVQRSVIILKDVLDEPLAEIAALLGISVDAVKA
HLSRGRARLREINARTDPFPDARIASANVVRYINLFNQRDWDGLRALLAEDVRLQQSMHPPRSGAADVGMFFTIYAKSEG
LWLKPAWVEGREVIAVFEHRAAPKPTHFMWLEWREGRISFIRDYRYVGYVADDARLVLASDVRSSGHGTKL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 34912; Mature: 34912

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGGKPGVERDRREALLALAAALRPELHRYCARLMGSVIDGEDVVQDTFARAFVALDELC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AVPQLRPWLFRIAHNRALDLLRSRATRVAEPIEAALEIVDDSKADAVETLMRKEAIETAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SRFAELPVVQRSVIILKDVLDEPLAEIAALLGISVDAVKAHLSRGRARLREINARTDPFP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DARIASANVVRYINLFNQRDWDGLRALLAEDVRLQQSMHPPRSGAADVGMFFTIYAKSEG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
LWLKPAWVEGREVIAVFEHRAAPKPTHFMWLEWREGRISFIRDYRYVGYVADDARLVLAS
CEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHEEEEECCCEEEEEH
DVRSSGHGTKL
HHHCCCCCCCC
>Mature Secondary Structure
MNGGKPGVERDRREALLALAAALRPELHRYCARLMGSVIDGEDVVQDTFARAFVALDELC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AVPQLRPWLFRIAHNRALDLLRSRATRVAEPIEAALEIVDDSKADAVETLMRKEAIETAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SRFAELPVVQRSVIILKDVLDEPLAEIAALLGISVDAVKAHLSRGRARLREINARTDPFP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DARIASANVVRYINLFNQRDWDGLRALLAEDVRLQQSMHPPRSGAADVGMFFTIYAKSEG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
LWLKPAWVEGREVIAVFEHRAAPKPTHFMWLEWREGRISFIRDYRYVGYVADDARLVLAS
CEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHEEEEECCCEEEEEH
DVRSSGHGTKL
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]