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The map label for this gene is macB [H]

Identifier: 13471429

GI number: 13471429

Start: 1169548

End: 1170765

Strand: Direct

Name: macB [H]

Synonym: mlr1397

Alternate gene names: 13471429

Gene position: 1169548-1170765 (Clockwise)

Preceding gene: 13471428

Following gene: 13471430

Centisome position: 16.62

GC content: 67.08

Gene sequence:

>1218_bases
ATGATCTGGGAAACCGTCCGCCTGTCGCTGCGCTCGATCCGCCGCAATGTGCTGCGCTCGTTCCTGACGCTGCTCGGCAT
CGTCATCGGCGTCGCCGCCGTCATTGCCATGCTGACCATCGGCTCCGGCACCACGCAGAAGGTCAAGGCCGACATCTCCA
AGCTCGGCAGCAATCTTCTGGTTGTCCGCGCCGGCCGCCCGGCTGGCCCCGGCGGTCCGGGCGGGCTTGACCAGGTGGTG
CGGCCGCTGGCCGAGAAGGACCTCGCGGCGCTGGTCGCGCATCTCACCGGCGCGCGCGCCATTTCGCCGGCCTCGCAAAA
ACAGGTGCGCGTCATCTTCGGCACCGAGAGCCTGACCTCCGGCGTCACCGGCACCGACAGCGCCTATCTCGATGCGCGCG
ACTGGAAGCTGGTGTCAGGCCGGCCGTTCAGCGATTCCGAAACCCGCTCGGGCACGGGCGTGTGCCTGATCGGCGAGACG
GTGCGCCAGCAATTCTTCGGCGCCGGCGATCCCGAAGGCGAGATCATCCGCGTCAACCGCACCTCCTGCAAGATCATCGG
CCTGCTCGAGCCCAAGGGCTACACCGGCTTCGGCCAGGACCAGGACAATGTCGTCCTGATGCCGCTGCATGCCTATCAGC
GCCGCATCGCCGGCAATCGTGACATCGACAACATCTACATCGCCGCCGATGACCGCACGCCGACCAGCGAGTTGCAGCCG
CGTGTCGAGGACATTTTGCGCGATATCAGGCGCATCACGCCGGATCGCGAAAGCGATTTCGCCATCCGCGACATGACGCA
GATCGCCGATGCCATGGCCAGCGCCACCACCACCATGACCGGCATGCTGGGCGCGGTCGCCGGCGTCAGTCTTCTGGTCG
GCGGCATCGGCATCATGAACATCATGCTGGTCTCGGTCACCGAGCGCACGCGCGAGATCGGCATCAGGCTGGCCATCGGG
GCGCACGAAAAGCACATCCTCATCCAATTCCTGGTCGAGGCGACGGTGCTGTCGCTGCTCGGCGGCATCATCGGCATCCT
GATCGGCCTGGGGCTCGCCGGCCTCGCCTCGGCGACGCTGACCATCCCCTTCGCGCCAAGCCCGGCGGTCATCCTGCTGG
CCGTCGGCTTCTCGGCGCTGATCGGCATGGTGTTCGGCTTCTTCCCGGCGCTGCGCGGCGCACGCCTCGATCCGATCGAC
GCGCTGCGGCACGAATAG

Upstream 100 bases:

>100_bases
TCACGCACGAGGCCGACGTCGCCGACTATGCCGAGCGCACCATCCGCTTCCTCGACGGCCATCTCGCCTCCGACACCGTG
AATGTCGAGGTGGCCTGACC

Downstream 100 bases:

>100_bases
GGCCACCCAGTCGGAAACGCTGCCGGCGCTCCAATCCGGTTTTTGCACAGCCTTCGACGCTTCCGCCCCGCCCCGCCACT
GTCGCCGCGCGGTTCACGAT

Product: permease protein of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MIWETVRLSLRSIRRNVLRSFLTLLGIVIGVAAVIAMLTIGSGTTQKVKADISKLGSNLLVVRAGRPAGPGGPGGLDQVV
RPLAEKDLAALVAHLTGARAISPASQKQVRVIFGTESLTSGVTGTDSAYLDARDWKLVSGRPFSDSETRSGTGVCLIGET
VRQQFFGAGDPEGEIIRVNRTSCKIIGLLEPKGYTGFGQDQDNVVLMPLHAYQRRIAGNRDIDNIYIAADDRTPTSELQP
RVEDILRDIRRITPDRESDFAIRDMTQIADAMASATTTMTGMLGAVAGVSLLVGGIGIMNIMLVSVTERTREIGIRLAIG
AHEKHILIQFLVEATVLSLLGGIIGILIGLGLAGLASATLTIPFAPSPAVILLAVGFSALIGMVFGFFPALRGARLDPID
ALRHE

Sequences:

>Translated_405_residues
MIWETVRLSLRSIRRNVLRSFLTLLGIVIGVAAVIAMLTIGSGTTQKVKADISKLGSNLLVVRAGRPAGPGGPGGLDQVV
RPLAEKDLAALVAHLTGARAISPASQKQVRVIFGTESLTSGVTGTDSAYLDARDWKLVSGRPFSDSETRSGTGVCLIGET
VRQQFFGAGDPEGEIIRVNRTSCKIIGLLEPKGYTGFGQDQDNVVLMPLHAYQRRIAGNRDIDNIYIAADDRTPTSELQP
RVEDILRDIRRITPDRESDFAIRDMTQIADAMASATTTMTGMLGAVAGVSLLVGGIGIMNIMLVSVTERTREIGIRLAIG
AHEKHILIQFLVEATVLSLLGGIIGILIGLGLAGLASATLTIPFAPSPAVILLAVGFSALIGMVFGFFPALRGARLDPID
ALRHE
>Mature_405_residues
MIWETVRLSLRSIRRNVLRSFLTLLGIVIGVAAVIAMLTIGSGTTQKVKADISKLGSNLLVVRAGRPAGPGGPGGLDQVV
RPLAEKDLAALVAHLTGARAISPASQKQVRVIFGTESLTSGVTGTDSAYLDARDWKLVSGRPFSDSETRSGTGVCLIGET
VRQQFFGAGDPEGEIIRVNRTSCKIIGLLEPKGYTGFGQDQDNVVLMPLHAYQRRIAGNRDIDNIYIAADDRTPTSELQP
RVEDILRDIRRITPDRESDFAIRDMTQIADAMASATTTMTGMLGAVAGVSLLVGGIGIMNIMLVSVTERTREIGIRLAIG
AHEKHILIQFLVEATVLSLLGGIIGILIGLGLAGLASATLTIPFAPSPAVILLAVGFSALIGMVFGFFPALRGARLDPID
ALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=409, Percent_Identity=33.0073349633252, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43008; Mature: 43008

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWETVRLSLRSIRRNVLRSFLTLLGIVIGVAAVIAMLTIGSGTTQKVKADISKLGSNLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEE
VVRAGRPAGPGGPGGLDQVVRPLAEKDLAALVAHLTGARAISPASQKQVRVIFGTESLTS
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHC
GVTGTDSAYLDARDWKLVSGRPFSDSETRSGTGVCLIGETVRQQFFGAGDPEGEIIRVNR
CCCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCEEEEEC
TSCKIIGLLEPKGYTGFGQDQDNVVLMPLHAYQRRIAGNRDIDNIYIAADDRTPTSELQP
CCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCH
RVEDILRDIRRITPDRESDFAIRDMTQIADAMASATTTMTGMLGAVAGVSLLVGGIGIMN
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERTREIGIRLAIGAHEKHILIQFLVEATVLSLLGGIIGILIGLGLAGLASATL
HHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TIPFAPSPAVILLAVGFSALIGMVFGFFPALRGARLDPIDALRHE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MIWETVRLSLRSIRRNVLRSFLTLLGIVIGVAAVIAMLTIGSGTTQKVKADISKLGSNLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEE
VVRAGRPAGPGGPGGLDQVVRPLAEKDLAALVAHLTGARAISPASQKQVRVIFGTESLTS
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHC
GVTGTDSAYLDARDWKLVSGRPFSDSETRSGTGVCLIGETVRQQFFGAGDPEGEIIRVNR
CCCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCEEEEEC
TSCKIIGLLEPKGYTGFGQDQDNVVLMPLHAYQRRIAGNRDIDNIYIAADDRTPTSELQP
CCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCH
RVEDILRDIRRITPDRESDFAIRDMTQIADAMASATTTMTGMLGAVAGVSLLVGGIGIMN
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERTREIGIRLAIGAHEKHILIQFLVEATVLSLLGGIIGILIGLGLAGLASATL
HHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TIPFAPSPAVILLAVGFSALIGMVFGFFPALRGARLDPIDALRHE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA