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The map label for this gene is lktD [H]

Identifier: 13470793

GI number: 13470793

Start: 453740

End: 455146

Strand: Direct

Name: lktD [H]

Synonym: mlr0589

Alternate gene names: 13470793

Gene position: 453740-455146 (Clockwise)

Preceding gene: 13470792

Following gene: 13470794

Centisome position: 6.45

GC content: 63.68

Gene sequence:

>1407_bases
ATGAGCAGCACCTCCCTCACCGCCCTTCCCGCTCGGTGGCACCGGATGGAAACGAGAGATCCGACGGCGCCGGCAATACT
CGAGTTCCAGTGGCCATCGACGGCTGTCGCCAATGCGCCTATTCCGCGGTCGGCGCGCGGCATCGTCTGGATCGTCTCTA
GCCTGGTCATCGCGCTGATCGCCCTGGCGGGGCTGATACCGGTCGATCAGGTGGTGACGGCCAGAGGGCTGGTGGTCTCG
CAATCCCCCAACATCGTTGTGCAACCGCTGGAAACAGCGATCGTCCGCTCGATCGAGGTGCGGGAAGGACAGCGCGTCCA
GGCCGGCCAATTGCTTGCCCGCCTCGATGCGACCTTTACCTCAGCCGACAAGGCGGCGCTGGCGATGCAGGTCTCGACGC
TTGAAGCCGAGGTGGCGCGGTTGAAGGCGGAGGCCAACGGCCAGGCGTTCACCTATGACGGCCTCGACCCGAGTTGGACC
CTGCAGGTGTCGATATTCGAGCAACGCAAGGCGGTCTACGACGCCAAGGTGGAGAATTTCGAACGCCAGCGTGACGAACT
CAGCTCGGTGATTTCGCGATCGCAATCCGATGCGGAGGGCTACCGCCAGCGGCTCACGGTCGCCGACTCGATCGAACAGA
TGCGCAGGCAGCTTGAGGCAAGGCAGGTAGGAAGTCGCCTCAACACGCTCCTGGCCGAGGACAACCGGGCGGAAATGTCC
CGGGCGCTGGGCAATGCCGAACAGACCGCGGAAGCCGCCAAGCGCCAGCAAGCCGCGGTGGCCGCCGAGCGCGACGGCTA
CATTCAGGGCTGGCGCGCTGAAGTCTCGCAGAGCCTGTCCGAGGCGAGCTCGCGGATCTCGGACGCCCGCGAACTTCTCA
ACAAGGCAAAGCTTCGAAACCAGTTGGTCGAGTTGAAGAGCCAATCAGACGCCATCGTTCAATCCGTGGCAAAAGTCTCT
GTCGGCTCGGTCATGCAGTCAGGGGAGCGCTTTATCACGCTGGTGCCGGCCGACGCGCCCCTTGAGATCGAGACAAACAT
CGTTGGCAGGAGCAGCGGTTTTGTGCATGTCGGCGACCCGGTGGTCATCAAGTTCGACACCTTCCCCTATTCGCAATACG
GCCTCGCCCATGGAACTGTGCGGGCACTCAGCCCAGATTCCTTCTCGGCACAGGAGCAAGCGCGCGATCCGAACAGTTCC
TTGGCCATGCTGCCTTCCGACGCCGAGCCATTCTATCGCACGCGGATCTCCATCGACCAGGTCGCCCTCCACGGCGTACC
CGCCGGTTTCGCCGTCAGCCCTGGCATGCCGGTGACCGCCGACGTAAAGGTCGGCCGCCGCACGATACTCAAGTACATTC
TCGGCGTCATGCTCCCGATCGGCCAGGAGGCAATGCGGGAGCCTTAG

Upstream 100 bases:

>100_bases
ACCGGCACCTCGACGGCCGCCACGGCCGCCCGGTCGCCGTCCCGCCGCGGTTGGTTTGATCATGTCGCGCGCCTCATATT
CGCATCAGGTCCGGTAACCC

Downstream 100 bases:

>100_bases
AGTACTGGAGGGATCAGAGGCTCGGATCGATGACAATCCTGGATCGGCTGACTGGTCTGGCCTTCCCGGCGGCGGTATTG
CGTCGAGCGATCAAGCTTGC

Product: secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSSTSLTALPARWHRMETRDPTAPAILEFQWPSTAVANAPIPRSARGIVWIVSSLVIALIALAGLIPVDQVVTARGLVVS
QSPNIVVQPLETAIVRSIEVREGQRVQAGQLLARLDATFTSADKAALAMQVSTLEAEVARLKAEANGQAFTYDGLDPSWT
LQVSIFEQRKAVYDAKVENFERQRDELSSVISRSQSDAEGYRQRLTVADSIEQMRRQLEARQVGSRLNTLLAEDNRAEMS
RALGNAEQTAEAAKRQQAAVAAERDGYIQGWRAEVSQSLSEASSRISDARELLNKAKLRNQLVELKSQSDAIVQSVAKVS
VGSVMQSGERFITLVPADAPLEIETNIVGRSSGFVHVGDPVVIKFDTFPYSQYGLAHGTVRALSPDSFSAQEQARDPNSS
LAMLPSDAEPFYRTRISIDQVALHGVPAGFAVSPGMPVTADVKVGRRTILKYILGVMLPIGQEAMREP

Sequences:

>Translated_468_residues
MSSTSLTALPARWHRMETRDPTAPAILEFQWPSTAVANAPIPRSARGIVWIVSSLVIALIALAGLIPVDQVVTARGLVVS
QSPNIVVQPLETAIVRSIEVREGQRVQAGQLLARLDATFTSADKAALAMQVSTLEAEVARLKAEANGQAFTYDGLDPSWT
LQVSIFEQRKAVYDAKVENFERQRDELSSVISRSQSDAEGYRQRLTVADSIEQMRRQLEARQVGSRLNTLLAEDNRAEMS
RALGNAEQTAEAAKRQQAAVAAERDGYIQGWRAEVSQSLSEASSRISDARELLNKAKLRNQLVELKSQSDAIVQSVAKVS
VGSVMQSGERFITLVPADAPLEIETNIVGRSSGFVHVGDPVVIKFDTFPYSQYGLAHGTVRALSPDSFSAQEQARDPNSS
LAMLPSDAEPFYRTRISIDQVALHGVPAGFAVSPGMPVTADVKVGRRTILKYILGVMLPIGQEAMREP
>Mature_467_residues
SSTSLTALPARWHRMETRDPTAPAILEFQWPSTAVANAPIPRSARGIVWIVSSLVIALIALAGLIPVDQVVTARGLVVSQ
SPNIVVQPLETAIVRSIEVREGQRVQAGQLLARLDATFTSADKAALAMQVSTLEAEVARLKAEANGQAFTYDGLDPSWTL
QVSIFEQRKAVYDAKVENFERQRDELSSVISRSQSDAEGYRQRLTVADSIEQMRRQLEARQVGSRLNTLLAEDNRAEMSR
ALGNAEQTAEAAKRQQAAVAAERDGYIQGWRAEVSQSLSEASSRISDARELLNKAKLRNQLVELKSQSDAIVQSVAKVSV
GSVMQSGERFITLVPADAPLEIETNIVGRSSGFVHVGDPVVIKFDTFPYSQYGLAHGTVRALSPDSFSAQEQARDPNSSL
AMLPSDAEPFYRTRISIDQVALHGVPAGFAVSPGMPVTADVKVGRRTILKYILGVMLPIGQEAMREP

Specific function: Involved in the transport of the Leukotoxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50901; Mature: 50770

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSLTALPARWHRMETRDPTAPAILEFQWPSTAVANAPIPRSARGIVWIVSSLVIALI
CCCCCCEECCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAGLIPVDQVVTARGLVVSQSPNIVVQPLETAIVRSIEVREGQRVQAGQLLARLDATFT
HHHCCCCHHHHHHHCCEEEECCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
SADKAALAMQVSTLEAEVARLKAEANGQAFTYDGLDPSWTLQVSIFEQRKAVYDAKVENF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHH
ERQRDELSSVISRSQSDAEGYRQRLTVADSIEQMRRQLEARQVGSRLNTLLAEDNRAEMS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALGNAEQTAEAAKRQQAAVAAERDGYIQGWRAEVSQSLSEASSRISDARELLNKAKLRN
HHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVELKSQSDAIVQSVAKVSVGSVMQSGERFITLVPADAPLEIETNIVGRSSGFVHVGDP
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCEEECCCE
VVIKFDTFPYSQYGLAHGTVRALSPDSFSAQEQARDPNSSLAMLPSDAEPFYRTRISIDQ
EEEEEECCCCHHHCCCCCEEEECCCCCCCCHHHCCCCCCCEEECCCCCCCHHHHHCCHHH
VALHGVPAGFAVSPGMPVTADVKVGRRTILKYILGVMLPIGQEAMREP
HHHCCCCCCCEECCCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
SSTSLTALPARWHRMETRDPTAPAILEFQWPSTAVANAPIPRSARGIVWIVSSLVIALI
CCCCCEECCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAGLIPVDQVVTARGLVVSQSPNIVVQPLETAIVRSIEVREGQRVQAGQLLARLDATFT
HHHCCCCHHHHHHHCCEEEECCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
SADKAALAMQVSTLEAEVARLKAEANGQAFTYDGLDPSWTLQVSIFEQRKAVYDAKVENF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHH
ERQRDELSSVISRSQSDAEGYRQRLTVADSIEQMRRQLEARQVGSRLNTLLAEDNRAEMS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALGNAEQTAEAAKRQQAAVAAERDGYIQGWRAEVSQSLSEASSRISDARELLNKAKLRN
HHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVELKSQSDAIVQSVAKVSVGSVMQSGERFITLVPADAPLEIETNIVGRSSGFVHVGDP
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCEEECCCE
VVIKFDTFPYSQYGLAHGTVRALSPDSFSAQEQARDPNSSLAMLPSDAEPFYRTRISIDQ
EEEEEECCCCHHHCCCCCEEEECCCCCCCCHHHCCCCCCCEEECCCCCCCHHHHHCCHHH
VALHGVPAGFAVSPGMPVTADVKVGRRTILKYILGVMLPIGQEAMREP
HHHCCCCCCCEECCCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040588; 2914876; 2707120 [H]