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The map label for this gene is hflX [H]

Identifier: 13470637

GI number: 13470637

Start: 289858

End: 291153

Strand: Direct

Name: hflX [H]

Synonym: mlr0403

Alternate gene names: 13470637

Gene position: 289858-291153 (Clockwise)

Preceding gene: 13470636

Following gene: 13470640

Centisome position: 4.12

GC content: 63.89

Gene sequence:

>1296_bases
GTGCCCGTGCTTACCCGCCAGCCGCGCGGTGACGACGACACCAACCGCCCACGGCTGACGCGCTCGGCCGACGCTCGCCA
TGACGAGGCGGTCGGCCTCGCGCGCGCCATCAATCTCGACCCAGTCCATACGGCTGTCGTGACCGTCAACGATCCGCGTC
CGGCGACCCTGCTTGGCAGCGGCAAGGTCGAAGAGTTCGCCCAAATCGTTAAGGACAACGACGCGGAACTGGTCATCGTC
GATCATCCGCTGACCCCGGTGCAGCAACGCAATCTCGAGAAGGAATTGCATGCCAAGGTTCTGGACCGAACCGGGCTGAT
CCTCGAAATCTTTGGCGAGCGCGCCCGCACCAAGGAAGGCACGCTGCAGGTCGAACTTGCCCATCTCAACTACCAGAAGG
GCCGCCTTGTGCGCAGCTGGACCCACCTTGAACGCCAGCGCGGTGGCGCCGGCTTCCTAGGCGGCCCCGGCGAAACCCAG
ATCGAATCCGACCGGCGGCAGTTGCAGGAAAAGATCATCAAGCTGAAGCACGAGCTGGAAACGGTGCGTCGCACCCGCGA
CCTGCACCGCGCCAAGCGCAAGAAGGTGCCATTCCCGGTGGTGGCGATCGTCGGCTACACCAATGCCGGCAAGTCGACGC
TGTTCAACCGGCTGACCGGAGCGGACGTGCTGGCGCAGGACATGCTGTTCGCCACGCTCGACCCGACGCTGCGCCGCGTG
CGCCTGCCGCATGGCACGCCGATCATCCTGTCGGACACGGTCGGTTTCATCTCCGATCTGCCGACGCATTTGATCGCGGC
TTTTCGCGCCACGCTGGAAGAGGTGGTCGAAGCCGATCTCGTCATTCATCTGCGCGACATCTCCGATCCCGACACGGCGG
CGCAGGCCGAGGATGTCGAGCGCATCCTGGCCGACCTCGGTGTCGACGCCGGTGACACCAAGCGTGTGATCGAAGTCTGG
AACAAGGTCGATCTGCTGGACGAAGGCAACAGGAGCCGCCTGCTTGCCGACGCCGTGGATGGCAGCAAAGGTCCGCCGAT
CGCCATATCGGCGGTGACCGGCGAGGGCATCGAAGCGCTGAAGGCGGTCATCGAGACACGCATGGCGGGCGAGCTCGAAG
ACCTGACGGTGACGATCGAGCCGGCACAGTTCGGCCTTGTCGATTGGCTGTATCGCAACGGCGATATCGTTTCGCGCGCC
GACAATGAAGACGGCAGCGCCACCATTTCGCTCAAGGCCACGCAAAGCGCCCGCGAAGAAATCGAAAGCCGATTGCGTCG
TAAAAACAACGGGTAA

Upstream 100 bases:

>100_bases
CTGATTGGCACGTGAAAAGGACGCGGACGCCACGGTTCGCGGAAAACCAGCGCATCATCCCGGGACGGAAGCCAAGGGGC
CGACCCGGGCTGTCGTCATT

Downstream 100 bases:

>100_bases
GCCGAAGAATTTCCAGTAAAAAGGCGGTTTTCCCTCCGGAATTGTCGGTCTATCGGCCCTATTTCGCGCTCTTCGCTTCC
TGCCAGAGCGCTTCCATCTC

Product: GTP binding protein-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPVLTRQPRGDDDTNRPRLTRSADARHDEAVGLARAINLDPVHTAVVTVNDPRPATLLGSGKVEEFAQIVKDNDAELVIV
DHPLTPVQQRNLEKELHAKVLDRTGLILEIFGERARTKEGTLQVELAHLNYQKGRLVRSWTHLERQRGGAGFLGGPGETQ
IESDRRQLQEKIIKLKHELETVRRTRDLHRAKRKKVPFPVVAIVGYTNAGKSTLFNRLTGADVLAQDMLFATLDPTLRRV
RLPHGTPIILSDTVGFISDLPTHLIAAFRATLEEVVEADLVIHLRDISDPDTAAQAEDVERILADLGVDAGDTKRVIEVW
NKVDLLDEGNRSRLLADAVDGSKGPPIAISAVTGEGIEALKAVIETRMAGELEDLTVTIEPAQFGLVDWLYRNGDIVSRA
DNEDGSATISLKATQSAREEIESRLRRKNNG

Sequences:

>Translated_431_residues
MPVLTRQPRGDDDTNRPRLTRSADARHDEAVGLARAINLDPVHTAVVTVNDPRPATLLGSGKVEEFAQIVKDNDAELVIV
DHPLTPVQQRNLEKELHAKVLDRTGLILEIFGERARTKEGTLQVELAHLNYQKGRLVRSWTHLERQRGGAGFLGGPGETQ
IESDRRQLQEKIIKLKHELETVRRTRDLHRAKRKKVPFPVVAIVGYTNAGKSTLFNRLTGADVLAQDMLFATLDPTLRRV
RLPHGTPIILSDTVGFISDLPTHLIAAFRATLEEVVEADLVIHLRDISDPDTAAQAEDVERILADLGVDAGDTKRVIEVW
NKVDLLDEGNRSRLLADAVDGSKGPPIAISAVTGEGIEALKAVIETRMAGELEDLTVTIEPAQFGLVDWLYRNGDIVSRA
DNEDGSATISLKATQSAREEIESRLRRKNNG
>Mature_430_residues
PVLTRQPRGDDDTNRPRLTRSADARHDEAVGLARAINLDPVHTAVVTVNDPRPATLLGSGKVEEFAQIVKDNDAELVIVD
HPLTPVQQRNLEKELHAKVLDRTGLILEIFGERARTKEGTLQVELAHLNYQKGRLVRSWTHLERQRGGAGFLGGPGETQI
ESDRRQLQEKIIKLKHELETVRRTRDLHRAKRKKVPFPVVAIVGYTNAGKSTLFNRLTGADVLAQDMLFATLDPTLRRVR
LPHGTPIILSDTVGFISDLPTHLIAAFRATLEEVVEADLVIHLRDISDPDTAAQAEDVERILADLGVDAGDTKRVIEVWN
KVDLLDEGNRSRLLADAVDGSKGPPIAISAVTGEGIEALKAVIETRMAGELEDLTVTIEPAQFGLVDWLYRNGDIVSRAD
NEDGSATISLKATQSAREEIESRLRRKNNG

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=301, Percent_Identity=34.5514950166113, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI310133116, Length=289, Percent_Identity=34.9480968858132, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI310124269, Length=270, Percent_Identity=35.5555555555556, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124267, Length=270, Percent_Identity=35.5555555555556, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124171, Length=270, Percent_Identity=35.5555555555556, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124169, Length=270, Percent_Identity=35.5555555555556, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1790615, Length=361, Percent_Identity=45.4293628808864, Blast_Score=285, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=403, Percent_Identity=33.2506203473945, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24650079, Length=366, Percent_Identity=36.6120218579235, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47584; Mature: 47452

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLTRQPRGDDDTNRPRLTRSADARHDEAVGLARAINLDPVHTAVVTVNDPRPATLLGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEECC
GKVEEFAQIVKDNDAELVIVDHPLTPVQQRNLEKELHAKVLDRTGLILEIFGERARTKEG
CCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEECCCHHCCCCC
TLQVELAHLNYQKGRLVRSWTHLERQRGGAGFLGGPGETQIESDRRQLQEKIIKLKHELE
EEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TVRRTRDLHRAKRKKVPFPVVAIVGYTNAGKSTLFNRLTGADVLAQDMLFATLDPTLRRV
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHE
RLPHGTPIILSDTVGFISDLPTHLIAAFRATLEEVVEADLVIHLRDISDPDTAAQAEDVE
ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHH
RILADLGVDAGDTKRVIEVWNKVDLLDEGNRSRLLADAVDGSKGPPIAISAVTGEGIEAL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHH
KAVIETRMAGELEDLTVTIEPAQFGLVDWLYRNGDIVSRADNEDGSATISLKATQSAREE
HHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECHHHHHH
IESRLRRKNNG
HHHHHHHCCCC
>Mature Secondary Structure 
PVLTRQPRGDDDTNRPRLTRSADARHDEAVGLARAINLDPVHTAVVTVNDPRPATLLGS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEECC
GKVEEFAQIVKDNDAELVIVDHPLTPVQQRNLEKELHAKVLDRTGLILEIFGERARTKEG
CCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEECCCHHCCCCC
TLQVELAHLNYQKGRLVRSWTHLERQRGGAGFLGGPGETQIESDRRQLQEKIIKLKHELE
EEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TVRRTRDLHRAKRKKVPFPVVAIVGYTNAGKSTLFNRLTGADVLAQDMLFATLDPTLRRV
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHE
RLPHGTPIILSDTVGFISDLPTHLIAAFRATLEEVVEADLVIHLRDISDPDTAAQAEDVE
ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHH
RILADLGVDAGDTKRVIEVWNKVDLLDEGNRSRLLADAVDGSKGPPIAISAVTGEGIEAL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHH
KAVIETRMAGELEDLTVTIEPAQFGLVDWLYRNGDIVSRADNEDGSATISLKATQSAREE
HHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECHHHHHH
IESRLRRKNNG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]