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The map label for this gene is hfq [H]

Identifier: 13470636

GI number: 13470636

Start: 289516

End: 289761

Strand: Direct

Name: hfq [H]

Synonym: mlr0402

Alternate gene names: 13470636

Gene position: 289516-289761 (Clockwise)

Preceding gene: 13470635

Following gene: 13470637

Centisome position: 4.11

GC content: 57.32

Gene sequence:

>246_bases
ATGGCGGAACGATCGCAAAACCTTCAGGACCTGTTCCTGAATTCAGTTCGCAAGAGCAAGAACCCGCTCACCATCTTCCT
CATCAACGGCGTGAAGCTGACCGGCGTGGTCACTTCGTTCGACAATTTCTGTGTGCTGCTGCGCCGCGACGGTCACTCCC
AGCTCGTCTACAAGCACGCCATTTCCACGATCATGCCGAGCCAGCCGGTTCAGATGTTCGATGGCGAGGAAAGCCAGGGC
GCCTGA

Upstream 100 bases:

>100_bases
TCGTTACTGACGACAAGACGGTGTTTGTGCGCTTGACATGTGCCCGTTAATTTGGCGCATTGGCCTGCAAACCGAAGGGG
ATCGGCGAAAGACAAGAACA

Downstream 100 bases:

>100_bases
TTGGCACGTGAAAAGGACGCGGACGCCACGGTTCGCGGAAAACCAGCGCATCATCCCGGGACGGAAGCCAAGGGGCCGAC
CCGGGCTGTCGTCATTGTGC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MAERSQNLQDLFLNSVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFDGEESQG
A

Sequences:

>Translated_81_residues
MAERSQNLQDLFLNSVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFDGEESQG
A
>Mature_80_residues
AERSQNLQDLFLNSVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFDGEESQGA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=82, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9069; Mature: 8937

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSQNLQDLFLNSVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQMFDGEESQGA
HHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AERSQNLQDLFLNSVRKSKNPLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQMFDGEESQGA
HHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA