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The map label for this gene is bkdR [H]

Identifier: 13470605

GI number: 13470605

Start: 257163

End: 257636

Strand: Direct

Name: bkdR [H]

Synonym: mlr0363

Alternate gene names: 13470605

Gene position: 257163-257636 (Clockwise)

Preceding gene: 13470602

Following gene: 13470607

Centisome position: 3.65

GC content: 58.23

Gene sequence:

>474_bases
ATGCCGCTCGACAGGATCGATATCGCCATTCTCGAGACTTTGCAGAAGGATGGCAGGATACCCAATGCCGCGCTCGCCGA
GAAGGTTGGCCTGTCGCAGTCGGCCTGTTCGCGCCGGCTCGATAATTTGGAAAAATCCGGCACTATCCGCGGCTACCATG
CCCGGCTGTCCAATGCCGCACTCGGTCATCAGATGACGGCGATCGTGCATATATCGCTGTCGGGCCAATTCGAGAAGACG
CTGTCGGATTTCGAAGCAGCGATCAAGCGTTGCCCCAATGTCTTGTCCTGCCACCTGATGTCGGGCGAATACGACTACAT
CCTGCGCATCGCGGCGAAAGACCTGGTCGACTATGAGCGCATCCACAAGGAATGGCTGTCGGCCATGCCGCATGTGACCA
AGATCAACTCGTCCTTCGCCTTGCGCGAAATCGTCGACCGCACCGCCATGGGGATGAAGCCGGAGATGGCTTGA

Upstream 100 bases:

>100_bases
ATGAATCGGCTCGCAAGTGTTTGCGAATGCGCTTGCGTGTGCAGGCCGGTTTCGATAATCCTTGCGTAAAATAGCAGGAT
ATTCGCAGGATTCACGAAAA

Downstream 100 bases:

>100_bases
GTTTGCCGGCCTGACCTTGCTCTCGACAGGCTTCAGGCTTCAGTGACAATTCGATCCATCGGAATGTCGTGCGGCTGCGG
ACAGATGGTGGCGATGCGCT

Product: leucine-responsive regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MPLDRIDIAILETLQKDGRIPNAALAEKVGLSQSACSRRLDNLEKSGTIRGYHARLSNAALGHQMTAIVHISLSGQFEKT
LSDFEAAIKRCPNVLSCHLMSGEYDYILRIAAKDLVDYERIHKEWLSAMPHVTKINSSFALREIVDRTAMGMKPEMA

Sequences:

>Translated_157_residues
MPLDRIDIAILETLQKDGRIPNAALAEKVGLSQSACSRRLDNLEKSGTIRGYHARLSNAALGHQMTAIVHISLSGQFEKT
LSDFEAAIKRCPNVLSCHLMSGEYDYILRIAAKDLVDYERIHKEWLSAMPHVTKINSSFALREIVDRTAMGMKPEMA
>Mature_156_residues
PLDRIDIAILETLQKDGRIPNAALAEKVGLSQSACSRRLDNLEKSGTIRGYHARLSNAALGHQMTAIVHISLSGQFEKTL
SDFEAAIKRCPNVLSCHLMSGEYDYILRIAAKDLVDYERIHKEWLSAMPHVTKINSSFALREIVDRTAMGMKPEMA

Specific function: Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=142, Percent_Identity=35.9154929577465, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI87081742, Length=148, Percent_Identity=33.1081081081081, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17510; Mature: 17378

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDRIDIAILETLQKDGRIPNAALAEKVGLSQSACSRRLDNLEKSGTIRGYHARLSNAA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGHQMTAIVHISLSGQFEKTLSDFEAAIKRCPNVLSCHLMSGEYDYILRIAAKDLVDYER
HHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHH
IHKEWLSAMPHVTKINSSFALREIVDRTAMGMKPEMA
HHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PLDRIDIAILETLQKDGRIPNAALAEKVGLSQSACSRRLDNLEKSGTIRGYHARLSNAA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGHQMTAIVHISLSGQFEKTLSDFEAAIKRCPNVLSCHLMSGEYDYILRIAAKDLVDYER
HHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHH
IHKEWLSAMPHVTKINSSFALREIVDRTAMGMKPEMA
HHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320210 [H]