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The map label for this gene is arsC [H]

Identifier: 15603809

GI number: 15603809

Start: 2179908

End: 2180312

Strand: Reverse

Name: arsC [H]

Synonym: PM1944

Alternate gene names: 15603809

Gene position: 2180312-2179908 (Counterclockwise)

Preceding gene: 15603811

Following gene: 15603808

Centisome position: 96.58

GC content: 43.95

Gene sequence:

>405_bases
ATGAACATTACCATTTATCACAACTCAAACTGCGGTACTTCACGCAATGTGCTGGCACTCATCCGCCACGCTGGTATTGA
GCCACAAGTGATTGAATATTTGAAAAATCCGCCAAGTGAAACGACTTTGCGTAATTTAATCAAACGCATGGGCATCACGC
CCCGCCAGTTACTTAGGACGAATGTAGTGCCGTATGAAACGCTTGGTTTGCAAAACGAAAAGTTAAGCGATGACGAACTC
ATTTCCGCCATGCTTCGTGAACCGATTTTAATCAATCGTCCGATTGTGGTGAGCGAAAAAGGCGTGAAATTATGCCGTCC
GTCCGAAACAGTTTTGGCATTTTTACCGCCTTTTGCGATCCCGTTTGTCAAAGAAGACGGCGAAATTATTAATCATAAGG
AGTAA

Upstream 100 bases:

>100_bases
AACTGCTGTTCTCAAACAGGCGAATCTTGCCAGTGATTTTCAGGCAGCCTGAAAAATTATTGCCAAATATTTCTATATTT
CTTGAAAGATTGGAGTAACT

Downstream 100 bases:

>100_bases
ATCATGGGGTTGTTTGAACGTTTTTTAAGCCTTTGGGTGGCGTTGGCGATTGTGCTGGGCGTGGTTTTGAGTGTTTGGTT
GCCCAATGTATTTCAATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MNITIYHNSNCGTSRNVLALIRHAGIEPQVIEYLKNPPSETTLRNLIKRMGITPRQLLRTNVVPYETLGLQNEKLSDDEL
ISAMLREPILINRPIVVSEKGVKLCRPSETVLAFLPPFAIPFVKEDGEIINHKE

Sequences:

>Translated_134_residues
MNITIYHNSNCGTSRNVLALIRHAGIEPQVIEYLKNPPSETTLRNLIKRMGITPRQLLRTNVVPYETLGLQNEKLSDDEL
ISAMLREPILINRPIVVSEKGVKLCRPSETVLAFLPPFAIPFVKEDGEIINHKE
>Mature_134_residues
MNITIYHNSNCGTSRNVLALIRHAGIEPQVIEYLKNPPSETTLRNLIKRMGITPRQLLRTNVVPYETLGLQNEKLSDDEL
ISAMLREPILINRPIVVSEKGVKLCRPSETVLAFLPPFAIPFVKEDGEIINHKE

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=128, Percent_Identity=59.375, Blast_Score=148, Evalue=1e-37,
Organism=Escherichia coli, GI1788841, Length=115, Percent_Identity=40, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15155; Mature: 15155

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITIYHNSNCGTSRNVLALIRHAGIEPQVIEYLKNPPSETTLRNLIKRMGITPRQLLRT
CEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
NVVPYETLGLQNEKLSDDELISAMLREPILINRPIVVSEKGVKLCRPSETVLAFLPPFAI
CCCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCCCCEEEECCCCCC
PFVKEDGEIINHKE
CEECCCCCCCCCCC
>Mature Secondary Structure
MNITIYHNSNCGTSRNVLALIRHAGIEPQVIEYLKNPPSETTLRNLIKRMGITPRQLLRT
CEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
NVVPYETLGLQNEKLSDDELISAMLREPILINRPIVVSEKGVKLCRPSETVLAFLPPFAI
CCCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCCCCEEEECCCCCC
PFVKEDGEIINHKE
CEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]