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The map label for this gene is trpR

Identifier: 15602190

GI number: 15602190

Start: 379942

End: 380250

Strand: Reverse

Name: trpR

Synonym: PM0325

Alternate gene names: 15602190

Gene position: 380250-379942 (Counterclockwise)

Preceding gene: 15602191

Following gene: 15602189

Centisome position: 16.84

GC content: 43.37

Gene sequence:

>309_bases
ATGTACTTAAGTCGCAATCTTGAACAATGGCATGCTTTCGTCGAAATGTTACGCACCGCATTCGCCCAAGGCAAAGAGCA
GGAAATCTTAACTCTCTTGCTCACCCCTGACGAACGAGACTCCGTCGGACTACGCTTACAAATTGTCGCTCAATTATTAG
ATAAAAGCGTACCCCAACGCGAAATTCAGCAAAATCTCAATACCAGCGCAGCCACCATTACTCGTGGCTCAAATATGATT
AAAACCATGCCACCTGAATTTATGGCGTGGGTAAAAGAACAATTAGATGAGCAAGCTAAAAAAGACTAA

Upstream 100 bases:

>100_bases
ATGTGTATTATCAGTGGCTACAACAGCAACCACAGCAAAAATTTAGCCAAGATGAATATAATCGATTATACTAGTGCGAT
AGTCAAAGGGAGGAAATACT

Downstream 100 bases:

>100_bases
GCATCCTTTTCCTTGTTTCAGTATTTGGCAACAATTTAAACGCAAACTTTACCGCACTTTTGCACTATTTCTCGTGCTGT
TTCTTTCAAGTGTGGTACTG

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MYLSRNLEQWHAFVEMLRTAFAQGKEQEILTLLLTPDERDSVGLRLQIVAQLLDKSVPQREIQQNLNTSAATITRGSNMI
KTMPPEFMAWVKEQLDEQAKKD

Sequences:

>Translated_102_residues
MYLSRNLEQWHAFVEMLRTAFAQGKEQEILTLLLTPDERDSVGLRLQIVAQLLDKSVPQREIQQNLNTSAATITRGSNMI
KTMPPEFMAWVKEQLDEQAKKD
>Mature_102_residues
MYLSRNLEQWHAFVEMLRTAFAQGKEQEILTLLLTPDERDSVGLRLQIVAQLLDKSVPQREIQQNLNTSAATITRGSNMI
KTMPPEFMAWVKEQLDEQAKKD

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

Organism=Escherichia coli, GI1790854, Length=88, Percent_Identity=42.0454545454545, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_PASMU (Q9CNU9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245262.1
- ProteinModelPortal:   Q9CNU9
- SMR:   Q9CNU9
- GeneID:   1243672
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0325
- NMPDR:   fig|272843.1.peg.325
- HOGENOM:   HBG677773
- OMA:   ELMRGEM
- ProtClustDB:   PRK01381
- BioCyc:   PMUL272843:PM0325-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 11774; Mature: 11774

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLSRNLEQWHAFVEMLRTAFAQGKEQEILTLLLTPDERDSVGLRLQIVAQLLDKSVPQR
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCHH
EIQQNLNTSAATITRGSNMIKTMPPEFMAWVKEQLDEQAKKD
HHHHCCCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLSRNLEQWHAFVEMLRTAFAQGKEQEILTLLLTPDERDSVGLRLQIVAQLLDKSVPQR
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCHH
EIQQNLNTSAATITRGSNMIKTMPPEFMAWVKEQLDEQAKKD
HHHHCCCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100