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The map label for this gene is rlrB

Identifier: 15673858

GI number: 15673858

Start: 1945945

End: 1946823

Strand: Reverse

Name: rlrB

Synonym: L0215

Alternate gene names: 15673858

Gene position: 1946823-1945945 (Counterclockwise)

Preceding gene: 15673859

Following gene: 15673857

Centisome position: 82.3

GC content: 36.06

Gene sequence:

>879_bases
ATGGAACTTCGATTATTAAAATATTTTTGGACAGTTGCAACTGCTGGAACAGTATCCAAAGCTGCTGAACAGTTATATAT
TACGCAGCCAACATTATCTAGACAAATTAAAGAACTTGAACGCGAACTAGATACACAACTTTTTATGCGTGATGGGAAAA
AACTGATCTTAACTGAAGATGGACAATTTCTTAAAATTAAGGCTGAGGAAATTTTACAGCTGACCAGTAAAACAGTACAA
GTTTTTGAAGACCGAAAAAATGCAGAATTATCTGGCCATCTGACGATCGGTGCTTTAGAAGGCTGGACAACTTCCAGTAT
CGCTAAAACGCTCCAAAGACTGACAAATAAATATCCGTCAATTACTTTAACAATTTTGTCAGGAAATGCTGATGATATCA
AATGGAAGATTGACAACGGACTAGTTGATGTTGGTTTTTTGTTAGAGCCAACATCAACTGAAAAATATAATGTTGAAAAA
ATTGGTTTTCCTGAACGTTGGATGATGCTCACTCAATCCGATTCAGAACTTGCAGAATTAGATGAAGTAAGTCCAGAAAT
ATTTAAAAAGCAAAGAATATTAATTTCAGAACGACCAGAAGTTCGTCAATTTATAGCCGATTGGGCAGGCTGCCAAGTGA
GTGATTTAGAAATTATTGGCGGCTTTAATCTCGGTTTTCATCTTTTTGAAATTGCTCGTGCAGGAATTGGCGAAGCAGTT
GTTACAGAAGGGGCGCTTATTCGAGATTACCCTGATTTAAAAGCTATTCCATTGAGTCCGGAAGTGAAAACTTTAAGTGT
GCTTGCTTGGAAGAAAAATATTCCACTGACTCCTCTTACAAGAGCATTTATTAAGCAATATCTTCAAGATAATGAATAA

Upstream 100 bases:

>100_bases
ATTCAAAATTGAAAATTATGATGAAGTGATGTTGCCAAATGAAATTAATTTGAACCAGAGTTCAAAAGAAACAATCAAGA
TTTAAATAGGAAAAGAATAA

Downstream 100 bases:

>100_bases
AAAGTTACTGACAGAAATTAGAGCATATTTGTAAAGACTAAAGTGTCAACAGCTATTCTCAGACAGCTCTGTCAGTAACT
TTTTTGTCAGTATTATGCTT

Product: LysR family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTTSSIAKTLQRLTNKYPSITLTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVSPEIFKKQRILISERPEVRQFIADWAGCQVSDLEIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRDYPDLKAIPLSPEVKTLSVLAWKKNIPLTPLTRAFIKQYLQDNE

Sequences:

>Translated_292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTTSSIAKTLQRLTNKYPSITLTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVSPEIFKKQRILISERPEVRQFIADWAGCQVSDLEIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRDYPDLKAIPLSPEVKTLSVLAWKKNIPLTPLTRAFIKQYLQDNE
>Mature_292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTTSSIAKTLQRLTNKYPSITLTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVSPEIFKKQRILISERPEVRQFIADWAGCQVSDLEIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRDYPDLKAIPLSPEVKTLSVLAWKKNIPLTPLTRAFIKQYLQDNE

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=26.1168384879725, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=25.6916996047431, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788887, Length=184, Percent_Identity=29.8913043478261, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=30.6666666666667, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788748, Length=286, Percent_Identity=25.5244755244755, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788296, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=158, Percent_Identity=28.4810126582279, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=290, Percent_Identity=23.448275862069, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=128, Percent_Identity=32.8125, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790399, Length=147, Percent_Identity=25.8503401360544, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=132, Percent_Identity=30.3030303030303, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367136, Length=120, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=161, Percent_Identity=32.2981366459627, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33063; Mature: 33063

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTED
CCEEHHHHHHHHHCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GQFLKIKAEEILQLTSKTVQVFEDRKNAELSGHLTIGALEGWTTSSIAKTLQRLTNKYPS
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCEECEEEEEEECCCCHHHHHHHHHHHHCCCCC
ITLTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEKIGFPERWMMLTQSDSELAEL
EEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEEECCCHHHHHH
DEVSPEIFKKQRILISERPEVRQFIADWAGCQVSDLEIIGGFNLGFHLFEIARAGIGEAV
HHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECEEEEECCCHHHHHHHHHHCCCCHHH
VTEGALIRDYPDLKAIPLSPEVKTLSVLAWKKNIPLTPLTRAFIKQYLQDNE
HHCCCEEECCCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTED
CCEEHHHHHHHHHCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GQFLKIKAEEILQLTSKTVQVFEDRKNAELSGHLTIGALEGWTTSSIAKTLQRLTNKYPS
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCEECEEEEEEECCCCHHHHHHHHHHHHCCCCC
ITLTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEKIGFPERWMMLTQSDSELAEL
EEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEEECCCHHHHHH
DEVSPEIFKKQRILISERPEVRQFIADWAGCQVSDLEIIGGFNLGFHLFEIARAGIGEAV
HHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECEEEEECCCHHHHHHHHHHCCCCHHH
VTEGALIRDYPDLKAIPLSPEVKTLSVLAWKKNIPLTPLTRAFIKQYLQDNE
HHCCCEEECCCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]