| Definition | Lactococcus lactis subsp. lactis Il1403, complete genome. |
|---|---|
| Accession | NC_002662 |
| Length | 2,365,589 |
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The map label for this gene is yteC
Identifier: 15673856
GI number: 15673856
Start: 1943594
End: 1944439
Strand: Reverse
Name: yteC
Synonym: L126956
Alternate gene names: 15673856
Gene position: 1944439-1943594 (Counterclockwise)
Preceding gene: 15673857
Following gene: 30024057
Centisome position: 82.2
GC content: 32.39
Gene sequence:
>846_bases ATGCAAAGAAAATTAACATTAAATGATGGCAATGTCATTCCCCAATTCGGTTTGGGACTTTATCAGCTTCCAGAAGGAAC AGAAACGCAAAATATTGTAAAAACTGCCTTGGAATTAGGTTATCGTCATCTGGATACGTCACACGCTTATCAAAATGAAA CTTCTGTCGGTCAAGCAATTCAAGACTCAGAAATTTCAAATTCTGAAATCTGGATTACAAGCAAGCTTTGGCCTTCTGAT TATGAGCAAGCGCCAGAAGCAATTGAGCGAATGCTAAAACGCCTAAAAGTTAAACAAATTGATTTACTCTTATTGCATCA ACAGGTTGGAAATTATCGAAAAGCATGGATTGCTTTAGAAAATGCTGTAAAAGAGGGAAAGGTGAAATCAATTGGAATTT CAAATTTTGATGGAGAAAGATTAGTTGATTTATTTAATTTTGCTGATATCAAACCGAGTGTCATTCAAGTAGAAACTCAT CCTTATCATCAACAAGTAGAATTACAGGAATTTTTGAAACCTTATGGTACAAAAATTGAAAGTTGGTATCCTCTGGGACA TGGCGATAAAAACTTACTTGAAGAAAAAATATTTAAAAAAATGGCTAAAAAATATAATAAAACAGTCGCACAAATCATTT TGCGTTGGCATATTCAAGAGGGAATTATTGTTTTTCCACGCTCAACGCAAAAAGAACATTTAGCAGAAAATATAAATATT TTTGATTTTGAATTATCCTGCTCCGAAATAAAAGAAATTCGTAAATTAAATAAAAAACAACCTTATTTTACGATGACCTA TGAGGAGCAAGAAAAAAACTTTTTGTCATGGAAACTAGAAGACTAA
Upstream 100 bases:
>100_bases ATCATTTGGTCATGGGATTCATCACCGCTTTTCTATCAGTAGGCCTTCTTGTCTTAATTTTTACTAGAACAGACAATAAT AAAAAATAAAAGGAGAAAAA
Downstream 100 bases:
>100_bases AGCACAGATTCTTATGCTTTTATGCAAAAGTGATATACTTTAGAGAGTTAGAACTTTTAAAACAAAAAATAAAATCAAGC CTATATGGTCTTGATTTTTT
Product: oxidoreductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 281; Mature: 281
Protein sequence:
>281_residues MQRKLTLNDGNVIPQFGLGLYQLPEGTETQNIVKTALELGYRHLDTSHAYQNETSVGQAIQDSEISNSEIWITSKLWPSD YEQAPEAIERMLKRLKVKQIDLLLLHQQVGNYRKAWIALENAVKEGKVKSIGISNFDGERLVDLFNFADIKPSVIQVETH PYHQQVELQEFLKPYGTKIESWYPLGHGDKNLLEEKIFKKMAKKYNKTVAQIILRWHIQEGIIVFPRSTQKEHLAENINI FDFELSCSEIKEIRKLNKKQPYFTMTYEEQEKNFLSWKLED
Sequences:
>Translated_281_residues MQRKLTLNDGNVIPQFGLGLYQLPEGTETQNIVKTALELGYRHLDTSHAYQNETSVGQAIQDSEISNSEIWITSKLWPSD YEQAPEAIERMLKRLKVKQIDLLLLHQQVGNYRKAWIALENAVKEGKVKSIGISNFDGERLVDLFNFADIKPSVIQVETH PYHQQVELQEFLKPYGTKIESWYPLGHGDKNLLEEKIFKKMAKKYNKTVAQIILRWHIQEGIIVFPRSTQKEHLAENINI FDFELSCSEIKEIRKLNKKQPYFTMTYEEQEKNFLSWKLED >Mature_281_residues MQRKLTLNDGNVIPQFGLGLYQLPEGTETQNIVKTALELGYRHLDTSHAYQNETSVGQAIQDSEISNSEIWITSKLWPSD YEQAPEAIERMLKRLKVKQIDLLLLHQQVGNYRKAWIALENAVKEGKVKSIGISNFDGERLVDLFNFADIKPSVIQVETH PYHQQVELQEFLKPYGTKIESWYPLGHGDKNLLEEKIFKKMAKKYNKTVAQIILRWHIQEGIIVFPRSTQKEHLAENINI FDFELSCSEIKEIRKLNKKQPYFTMTYEEQEKNFLSWKLED
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=297, Percent_Identity=32.3232323232323, Blast_Score=171, Evalue=7e-43, Organism=Homo sapiens, GI5174391, Length=297, Percent_Identity=32.3232323232323, Blast_Score=171, Evalue=7e-43, Organism=Homo sapiens, GI223468663, Length=283, Percent_Identity=34.982332155477, Blast_Score=167, Evalue=7e-42, Organism=Homo sapiens, GI5174695, Length=296, Percent_Identity=33.7837837837838, Blast_Score=166, Evalue=3e-41, Organism=Homo sapiens, GI4502049, Length=295, Percent_Identity=35.2542372881356, Blast_Score=163, Evalue=2e-40, Organism=Homo sapiens, GI310109922, Length=280, Percent_Identity=34.6428571428571, Blast_Score=158, Evalue=5e-39, Organism=Homo sapiens, GI5453543, Length=301, Percent_Identity=32.5581395348837, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI310109920, Length=301, Percent_Identity=32.5581395348837, Blast_Score=154, Evalue=6e-38, Organism=Homo sapiens, GI45446745, Length=301, Percent_Identity=32.5581395348837, Blast_Score=154, Evalue=7e-38, Organism=Homo sapiens, GI4503285, Length=301, Percent_Identity=32.5581395348837, Blast_Score=154, Evalue=7e-38, Organism=Homo sapiens, GI291291012, Length=263, Percent_Identity=33.8403041825095, Blast_Score=154, Evalue=1e-37, Organism=Homo sapiens, GI24497583, Length=299, Percent_Identity=31.1036789297659, Blast_Score=150, Evalue=8e-37, Organism=Homo sapiens, GI24497585, Length=305, Percent_Identity=31.1475409836066, Blast_Score=150, Evalue=1e-36, Organism=Homo sapiens, GI300116273, Length=278, Percent_Identity=32.0143884892086, Blast_Score=147, Evalue=1e-35, Organism=Homo sapiens, GI93277124, Length=314, Percent_Identity=29.6178343949045, Blast_Score=142, Evalue=2e-34, Organism=Homo sapiens, GI300116271, Length=273, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=3e-34, Organism=Homo sapiens, GI310109924, Length=158, Percent_Identity=33.5443037974684, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI207028673, Length=113, Percent_Identity=38.0530973451327, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI310109926, Length=113, Percent_Identity=38.0530973451327, Blast_Score=78, Evalue=9e-15, Organism=Escherichia coli, GI87082198, Length=257, Percent_Identity=38.9105058365759, Blast_Score=205, Evalue=2e-54, Organism=Escherichia coli, GI1786400, Length=255, Percent_Identity=32.9411764705882, Blast_Score=135, Evalue=4e-33, Organism=Escherichia coli, GI1788081, Length=277, Percent_Identity=25.2707581227437, Blast_Score=86, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17537077, Length=294, Percent_Identity=36.0544217687075, Blast_Score=184, Evalue=5e-47, Organism=Caenorhabditis elegans, GI17537075, Length=294, Percent_Identity=36.0544217687075, Blast_Score=182, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17564128, Length=310, Percent_Identity=32.5806451612903, Blast_Score=164, Evalue=6e-41, Organism=Caenorhabditis elegans, GI17537079, Length=294, Percent_Identity=29.2517006802721, Blast_Score=146, Evalue=1e-35, Organism=Caenorhabditis elegans, GI17566692, Length=284, Percent_Identity=32.7464788732394, Blast_Score=145, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17538386, Length=276, Percent_Identity=32.6086956521739, Blast_Score=143, Evalue=1e-34, Organism=Caenorhabditis elegans, GI71998625, Length=257, Percent_Identity=31.1284046692607, Blast_Score=142, Evalue=3e-34, Organism=Caenorhabditis elegans, GI17561298, Length=279, Percent_Identity=29.3906810035842, Blast_Score=138, Evalue=4e-33, Organism=Caenorhabditis elegans, GI17552492, Length=265, Percent_Identity=30.5660377358491, Blast_Score=133, Evalue=9e-32, Organism=Caenorhabditis elegans, GI17562292, Length=278, Percent_Identity=28.7769784172662, Blast_Score=124, Evalue=5e-29, Organism=Caenorhabditis elegans, GI17561300, Length=279, Percent_Identity=28.673835125448, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17550248, Length=295, Percent_Identity=27.7966101694915, Blast_Score=115, Evalue=2e-26, Organism=Saccharomyces cerevisiae, GI6324694, Length=287, Percent_Identity=34.4947735191638, Blast_Score=166, Evalue=4e-42, Organism=Saccharomyces cerevisiae, GI6320576, Length=285, Percent_Identity=32.280701754386, Blast_Score=149, Evalue=5e-37, Organism=Saccharomyces cerevisiae, GI6319625, Length=296, Percent_Identity=32.4324324324324, Blast_Score=144, Evalue=2e-35, Organism=Saccharomyces cerevisiae, GI6322556, Length=269, Percent_Identity=32.7137546468402, Blast_Score=141, Evalue=1e-34, Organism=Saccharomyces cerevisiae, GI6321896, Length=308, Percent_Identity=30.5194805194805, Blast_Score=130, Evalue=2e-31, Organism=Saccharomyces cerevisiae, GI6320079, Length=284, Percent_Identity=29.2253521126761, Blast_Score=114, Evalue=2e-26, Organism=Drosophila melanogaster, GI24662789, Length=297, Percent_Identity=32.996632996633, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI45553081, Length=292, Percent_Identity=33.5616438356164, Blast_Score=155, Evalue=4e-38, Organism=Drosophila melanogaster, GI20129731, Length=296, Percent_Identity=32.0945945945946, Blast_Score=153, Evalue=1e-37, Organism=Drosophila melanogaster, GI24663317, Length=278, Percent_Identity=33.4532374100719, Blast_Score=152, Evalue=3e-37, Organism=Drosophila melanogaster, GI24644950, Length=298, Percent_Identity=29.1946308724832, Blast_Score=145, Evalue=3e-35, Organism=Drosophila melanogaster, GI24657054, Length=278, Percent_Identity=32.7338129496403, Blast_Score=144, Evalue=5e-35, Organism=Drosophila melanogaster, GI24662785, Length=278, Percent_Identity=35.9712230215827, Blast_Score=142, Evalue=3e-34, Organism=Drosophila melanogaster, GI221378297, Length=318, Percent_Identity=27.3584905660377, Blast_Score=137, Evalue=8e-33, Organism=Drosophila melanogaster, GI281366140, Length=260, Percent_Identity=32.6923076923077, Blast_Score=136, Evalue=2e-32, Organism=Drosophila melanogaster, GI24662781, Length=277, Percent_Identity=35.0180505415162, Blast_Score=136, Evalue=2e-32, Organism=Drosophila melanogaster, GI21356425, Length=301, Percent_Identity=29.5681063122924, Blast_Score=135, Evalue=2e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 32826; Mature: 32826
Theoretical pI: Translated: 6.73; Mature: 6.73
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQRKLTLNDGNVIPQFGLGLYQLPEGTETQNIVKTALELGYRHLDTSHAYQNETSVGQAI CCCEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH QDSEISNSEIWITSKLWPSDYEQAPEAIERMLKRLKVKQIDLLLLHQQVGNYRKAWIALE HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH NAVKEGKVKSIGISNFDGERLVDLFNFADIKPSVIQVETHPYHQQVELQEFLKPYGTKIE HHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC SWYPLGHGDKNLLEEKIFKKMAKKYNKTVAQIILRWHIQEGIIVFPRSTQKEHLAENINI CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCE FDFELSCSEIKEIRKLNKKQPYFTMTYEEQEKNFLSWKLED EEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECC >Mature Secondary Structure MQRKLTLNDGNVIPQFGLGLYQLPEGTETQNIVKTALELGYRHLDTSHAYQNETSVGQAI CCCEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH QDSEISNSEIWITSKLWPSDYEQAPEAIERMLKRLKVKQIDLLLLHQQVGNYRKAWIALE HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH NAVKEGKVKSIGISNFDGERLVDLFNFADIKPSVIQVETHPYHQQVELQEFLKPYGTKIE HHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC SWYPLGHGDKNLLEEKIFKKMAKKYNKTVAQIILRWHIQEGIIVFPRSTQKEHLAENINI CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCE FDFELSCSEIKEIRKLNKKQPYFTMTYEEQEKNFLSWKLED EEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9387221; 9384377 [H]