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The map label for this gene is atpA

Identifier: 15673748

GI number: 15673748

Start: 1825639

End: 1827141

Strand: Reverse

Name: atpA

Synonym: L8990

Alternate gene names: 15673748

Gene position: 1827141-1825639 (Counterclockwise)

Preceding gene: 15673749

Following gene: 15673747

Centisome position: 77.24

GC content: 41.45

Gene sequence:

>1503_bases
TTGGCAATTAAAGCTAATGAAATCAGCTCACTGATTAAAAAACAAATTGAAAATTTCACACCAGATTTTGAAGTTGCTGA
AACTGGTGTCGTTACCTATGTTGGTGACGGTATCGCCCGTGCCTATGGCCTTGAAAATGCGATGAGCGGTGAGCTTGTTG
AGTTTTCAAATGGTGTCCTTGGTATGGCGCAAAACTTGGATGCGACAGACGTTGGTATTATCGTACTTGGTGATTTCCTC
TCAATTCGTGAAGGTGACACTGTAAAACGTACAGGTAAAATCATGGAAATCCAAGTTGGTGAAGAACTCATCGGACGTGT
TGTAAATCCACTTGGACAACCTGTTGATGGACTTGGAGAACTTAATACTGGTAAAACTCGTCCTGTTGAAGCAAAAGCTC
CTGGTGTTATGCAACGTAAATCAGTCTCTGAACCATTGCAAACTGGTCTTAAAGCGATTGATGCCCTCGTTCCAATTGGA
CGCGGACAACGTGAATTGATTATCGGAGACCGTCAAACAGGTAAAACATCAGTCGCTATTGATGCAATCTTGAACCAAAA
GGGTCAAGATATGATCTGTATCTACGTTGCGATTGGACAAAAAGAATCAACTGTTCGTACACAAGTTGAAACGCTCCGCA
AACTCGGTGCGATGGATTATACAATCGTCGTAACTGCGTCAGCTTCTCAACCTTCACCACTTCTTTACATCGCTCCTTAT
GCTGGAGCTGCAATGGGTGAAGAATTCATGTACAACGGTAAACACGTCTTAGTTGTTTATGATGATTTATCAAAACAAGC
GGTTGCTTATCGTGAACTTTCACTCTTGCTCCGCCGTCCACCAGGTCGTGAAGCATACCCAGGTGACGTATTCTACTTAC
ATTCACGTCTTTTGGAACGTGCTGCCAAATTATCTGACGATCTTGGTGGTGGTTCAATGACTGCACTGCCATTCATTGAA
ACACAAGCCGGAGATATCTCAGCTTATATTGCAACAAACGTTATCTCTATTACTGACGGTCAAATTTTCCTTGAAAATGA
CTTATTCTATTCAGGTGTACGTCCTGCCATCGATGCTGGTTCTTCAGTTTCTCGGGTTGGTGGTGCTGCACAGATCAAAG
CCATGAAGAAAGTTGCTGGTACTTTGCGTCTTGACCTTGCGTCATTCCGTGAACTTGAAGCCTTTACTCAATTTGGTTCT
GATCTTGATGAAGCGACTCAAGCAAAATTGAATCGTGGTCGTCGTACCGTTGAAGTTTTGAAGCAACCATTGCACAAACC
ATTGGCTGTTGAAAAACAAGTTTTAATTCTTTATGCATTGACTCATGGTCATCTTGATGATGTTCCAGTTGATGACGTTC
TTGATTTTGAAACAAAAATGTTCGATTTCTTCGATGCAAATTATGCAGAACTCTTGAACGTGATTACTGAAACTAAAGAT
TTGCCAGAAGAAGCAAAACTCGACGAAGCAATTAAAGCATTCAAAAATACAACGAATTATTAA

Upstream 100 bases:

>100_bases
AGGTGATTTCAAATCTTACCTATCATGCTCAAACGGTATAACTGCAGTTTAAAGCTAAATAGCCTTGAACTAGTAAAAAT
TTCTAGAAGGGAGCATATTT

Downstream 100 bases:

>100_bases
TAAGGAGGCTAACTAATGGGAGCTTCACTTAATGAAATAAAAACTAAGATTGCCTCAACGAAGAAAACAAGTCAAATAAC
TGGAGCCATGCAAATGGTTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGVLGMAQNLDATDVGIIVLGDFL
SIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIE
TQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGS
DLDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDDVPVDDVLDFETKMFDFFDANYAELLNVITETKD
LPEEAKLDEAIKAFKNTTNY

Sequences:

>Translated_500_residues
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGVLGMAQNLDATDVGIIVLGDFL
SIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIE
TQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGS
DLDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDDVPVDDVLDFETKMFDFFDANYAELLNVITETKD
LPEEAKLDEAIKAFKNTTNY
>Mature_499_residues
AIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGVLGMAQNLDATDVGIIVLGDFLS
IREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPYA
GAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIET
QAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSD
LDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDDVPVDDVLDFETKMFDFFDANYAELLNVITETKDL
PEEAKLDEAIKAFKNTTNY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=58.2329317269076, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=58.2329317269076, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=27.2131147540984, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913428, Length=305, Percent_Identity=26.8852459016393, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI32189394, Length=383, Percent_Identity=25.065274151436, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=51.6569200779727, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.0882352941176, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790170, Length=406, Percent_Identity=24.6305418719212, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=57.7689243027888, Blast_Score=575, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=57.7689243027888, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=53.9840637450199, Blast_Score=523, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=26.3305322128852, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=27.0903010033445, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=415, Percent_Identity=23.3734939759036, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=74, Percent_Identity=43.2432432432432, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=504, Percent_Identity=57.3412698412698, Blast_Score=576, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=26.8852459016393, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322581, Length=412, Percent_Identity=24.0291262135922, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24658560, Length=504, Percent_Identity=57.5396825396825, Blast_Score=577, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24638766, Length=415, Percent_Identity=24.578313253012, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574560, Length=427, Percent_Identity=24.1217798594848, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129479, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_LACLA (Q9CER8)

Other databases:

- EMBL:   AF393838
- EMBL:   AB072443
- EMBL:   AE005176
- PIR:   F86845
- RefSeq:   NP_267922.1
- ProteinModelPortal:   Q9CER8
- SMR:   Q9CER8
- GeneID:   1115429
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L8990
- NMPDR:   fig|272623.1.peg.1810
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   LLAC272623:L8990-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01346
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54326; Mature: 54195

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGVL
CCCCHHHHHHHHHHHHHHCCCCCCHHCCCEEEEECCHHHHHHCCCCCCCCCCEECCCCCE
GMAQNLDATDVGIIVLGDFLSIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGE
EHHCCCCCCCEEEEEEECHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCC
LNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDDLGGGSMTALPFIETQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEECCEEEEECCCEECCCCHHHCCC
SSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSDLDEATQAKLNRGRRTVEVL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
KQPLHKPLAVEKQVLILYALTHGHLDDVPVDDVLDFETKMFDFFDANYAELLNVITETKD
HHHCCCCHHHCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPEEAKLDEAIKAFKNTTNY
CCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGVL
CCCHHHHHHHHHHHHHHCCCCCCHHCCCEEEEECCHHHHHHCCCCCCCCCCEECCCCCE
GMAQNLDATDVGIIVLGDFLSIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGE
EHHCCCCCCCEEEEEEECHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCC
LNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDDLGGGSMTALPFIETQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEECCEEEEECCCEECCCCHHHCCC
SSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSDLDEATQAKLNRGRRTVEVL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
KQPLHKPLAVEKQVLILYALTHGHLDDVPVDDVLDFETKMFDFFDANYAELLNVITETKD
HHHCCCCHHHCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPEEAKLDEAIKAFKNTTNY
CCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471