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The map label for this gene is deoC

Identifier: 15673422

GI number: 15673422

Start: 1463563

End: 1464225

Strand: Reverse

Name: deoC

Synonym: L63310

Alternate gene names: 15673422

Gene position: 1464225-1463563 (Counterclockwise)

Preceding gene: 15673423

Following gene: 15673421

Centisome position: 61.9

GC content: 36.8

Gene sequence:

>663_bases
ATGCAAATTAATAAATATATTGACCATACTATTCTTAAAGCCGATGCTCCAAAATCTAAAGTTCAACAAATAATTGATGA
AGCAAAAAAATATGATTTCATGAGCGTTTGTATTAACCCCACATGGGTAAGTTATGCCAGTCAAGAACTTAAAGACTCAG
ACGTTAAAGTATGTACAGTAATTGGTTTTCCTTTAGGTGCTAATACTTCTGAACTCAAAGCTTTTGAAGCTAAAAACGCT
ATTGAAAATGGTGCTGATGAAATTGACATGGTCATTAATATTGGCGCAGCCAAATCTAAGGATTGGAATCTTGTTGAGTC
AGATATCGCAGCTGTCAACGCAGTAAAAGGTGATAAACTTCTTAAAGTTATCATTGAAACAAGCCTTTTAACTGACGATG
AAAAGATTAAAGCTTGCCAAATTGCTAAAGCAGTTGGTGCTGATTTTGTCAAAACTTCAACAGGTTTCTCAACAGGTGGA
GCGACTGTTCATGATGTAAAATTAATGCGTCAAACGGTTGGCCCAGATATGGGAGTTAAGGCTTCTGGTGGAGTTCATAA
TCTTGAAGAAGCAAAAGCAATGATTGATGCTGGTGCAACACGTCTTGGTGTTTCGGCTGGTGTTGCAATTATGGAAGGTC
TGACTTCAAATGACAACTACTAA

Upstream 100 bases:

>100_bases
TTGGCTTATTCAACTTATTGCTTTTATCATTATCTTCGTTGTAGTCTATCTCATCGTTGGAATAATTTACTTAAGATTAA
AAAAATAGAAAGAACATAAA

Downstream 100 bases:

>100_bases
AAAAATGATTGCTGCCGCACGCGAAGCGGCGAGTTTGGCATATGTTCCTTACTCTCATTTTCCTGTAGGAGCAGCTTTTC
ATACAACTGATGGTCGAATT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTVIGFPLGANTSELKAFEAKNA
IENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKLLKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGG
ATVHDVKLMRQTVGPDMGVKASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY

Sequences:

>Translated_220_residues
MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTVIGFPLGANTSELKAFEAKNA
IENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKLLKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGG
ATVHDVKLMRQTVGPDMGVKASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY
>Mature_220_residues
MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTVIGFPLGANTSELKAFEAKNA
IENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKLLKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGG
ATVHDVKLMRQTVGPDMGVKASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=225, Percent_Identity=29.7777777777778, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1790841, Length=204, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533015, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922098, Length=185, Percent_Identity=30.2702702702703, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_LACLA (Q9CFM7)

Other databases:

- EMBL:   AE005176
- PIR:   H86804
- RefSeq:   NP_267596.1
- ProteinModelPortal:   Q9CFM7
- SMR:   Q9CFM7
- GeneID:   1115096
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L63310
- NMPDR:   fig|272623.1.peg.1481
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   LLAC272623:L63310-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23426; Mature: 23426

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: ACT_SITE 151-151 ACT_SITE 180-180

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTV
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCCCCEEEEE
IGFPLGANTSELKAFEAKNAIENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKL
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHH
LKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGGATVHDVKLMRQTVGPDMGVK
HHHHHHHHHCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
ASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTV
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCCCCEEEEE
IGFPLGANTSELKAFEAKNAIENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKL
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHH
LKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGGATVHDVKLMRQTVGPDMGVK
HHHHHHHHHCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
ASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471