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The map label for this gene is cdd

Identifier: 15673421

GI number: 15673421

Start: 1463184

End: 1463576

Strand: Reverse

Name: cdd

Synonym: L62931

Alternate gene names: 15673421

Gene position: 1463576-1463184 (Counterclockwise)

Preceding gene: 15673422

Following gene: 15673420

Centisome position: 61.87

GC content: 35.37

Gene sequence:

>393_bases
ATGACAACTACTAAAAAAATGATTGCTGCCGCACGCGAAGCGGCGAGTTTGGCATATGTTCCTTACTCTCATTTTCCTGT
AGGAGCAGCTTTTCATACAACTGATGGTCGAATTATCACAGGTTGTAATATTGAAAATGCTAGTTTTGGACTTTCTAATT
GTGCTGAACGAACAGCTATTTTTAAAGCAATATCAGAAGGCCTGAAAGATTTTGATGCTCTTTATGTATTCGGAGAAACA
GAAGAACCAATTAGCCCTTGTGGTGCTTGTAGACAAGTTATTGCAGAATTTTGTCCAGCAGATATGCCAGTTTTTTTGAT
TTCTAAAAATGATAATGTAAAAGAAACTTCAGTTGAGGAACTTTTACCATATTCTTTCAAAAATCTTGATTAA

Upstream 100 bases:

>100_bases
GGAGTTCATAATCTTGAAGAAGCAAAAGCAATGATTGATGCTGGTGCAACACGTCTTGGTGTTTCGGCTGGTGTTGCAAT
TATGGAAGGTCTGACTTCAA

Downstream 100 bases:

>100_bases
AATAAAATTGATATGCTATCAACAGGTAGCATATTAATTTGTAACTAAAGTAAGCGCTTTATCTTTTTTCTTTTAAAAAA
TGTAAAAATGGTAATTACTG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTTTKKMIAAAREAASLAYVPYSHFPVGAAFHTTDGRIITGCNIENASFGLSNCAERTAIFKAISEGLKDFDALYVFGET
EEPISPCGACRQVIAEFCPADMPVFLISKNDNVKETSVEELLPYSFKNLD

Sequences:

>Translated_130_residues
MTTTKKMIAAAREAASLAYVPYSHFPVGAAFHTTDGRIITGCNIENASFGLSNCAERTAIFKAISEGLKDFDALYVFGET
EEPISPCGACRQVIAEFCPADMPVFLISKNDNVKETSVEELLPYSFKNLD
>Mature_129_residues
TTTKKMIAAAREAASLAYVPYSHFPVGAAFHTTDGRIITGCNIENASFGLSNCAERTAIFKAISEGLKDFDALYVFGETE
EPISPCGACRQVIAEFCPADMPVFLISKNDNVKETSVEELLPYSFKNLD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=127, Percent_Identity=50.3937007874016, Blast_Score=126, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=46.7213114754098, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=141, Percent_Identity=46.8085106382979, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=120, Percent_Identity=40, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920920, Length=140, Percent_Identity=45, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582741, Length=133, Percent_Identity=45.8646616541353, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24582744, Length=141, Percent_Identity=41.1347517730496, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14152; Mature: 14021

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTKKMIAAAREAASLAYVPYSHFPVGAAFHTTDGRIITGCNIENASFGLSNCAERTAI
CCCHHHHHHHHHHHHHEEECCCCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHH
FKAISEGLKDFDALYVFGETEEPISPCGACRQVIAEFCPADMPVFLISKNDNVKETSVEE
HHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
LLPYSFKNLD
HCCCHHCCCC
>Mature Secondary Structure 
TTTKKMIAAAREAASLAYVPYSHFPVGAAFHTTDGRIITGCNIENASFGLSNCAERTAI
CCHHHHHHHHHHHHHEEECCCCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHH
FKAISEGLKDFDALYVFGETEEPISPCGACRQVIAEFCPADMPVFLISKNDNVKETSVEE
HHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
LLPYSFKNLD
HCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]