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The map label for this gene is yfiG

Identifier: 15672575

GI number: 15672575

Start: 584876

End: 585445

Strand: Direct

Name: yfiG

Synonym: L184871

Alternate gene names: 15672575

Gene position: 584876-585445 (Clockwise)

Preceding gene: 15672574

Following gene: 15672576

Centisome position: 24.72

GC content: 36.32

Gene sequence:

>570_bases
ATGGCGCAATTATATTTCAAATATGGGACGATGAATTCAGGGAAATCAATTGAGATTTTGAAAGTGGCTCATAATTATGA
GGAACAGGGTAAGCCTGTTTTATTAATGACTTCTAGTCTAGATACACGCGCAGGGGTTGGGACAGTTGCTAGTCGAATCG
GGATGAAAGCTGAAGCTGTCGCAATTGATGAGGAAATGTCTGTTTTTGATTATGTGAACAGCCTGCCAGCTAAACCTTTT
TGTGTGCTGATTGATGAGGCACAATTTTTAAATAAAAAACATGTCTATGATTTTGCGCGTGTTGTGGATGAACTAAATGT
TCCAGTCATGGCTTTTGGTTTGAAAAATGATTTTCGTAATGAGCTTTTTGAAGGCTCAAAATATTTACTTTTGCTTGCGG
ACAAAATCGAAGAAATTAAAACAATTTGTTGGTATTGTAGTAAAAAGGCAACAATGGTGATTCGGACAATTGATGGAAAA
CCAGTTTATGAAGGTGAACAGTTGCAGATTGGTGGAAACGAAACCTATATTCCTGTTTGTCGTAAACATTATTTTAAGCC
AGAAATTTAA

Upstream 100 bases:

>100_bases
TAGAGAAATCGAGAAAGTTTATGAAGTAATCTTTAAAGATTTTGAAGTACAGAACTTTTGATATCAATGGTATAGAAGCT
AAAAAATAAAAGGAAAAGTA

Downstream 100 bases:

>100_bases
AAAATAAGATTAGAATTTTACACGAACAGACTTTATATCAAGAGGGAGGAACTCGATGTTTTATCATTTTAAAGGAACGA
TTACTGGTGAGGATTATCAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAQLYFKYGTMNSGKSIEILKVAHNYEEQGKPVLLMTSSLDTRAGVGTVASRIGMKAEAVAIDEEMSVFDYVNSLPAKPF
CVLIDEAQFLNKKHVYDFARVVDELNVPVMAFGLKNDFRNELFEGSKYLLLLADKIEEIKTICWYCSKKATMVIRTIDGK
PVYEGEQLQIGGNETYIPVCRKHYFKPEI

Sequences:

>Translated_189_residues
MAQLYFKYGTMNSGKSIEILKVAHNYEEQGKPVLLMTSSLDTRAGVGTVASRIGMKAEAVAIDEEMSVFDYVNSLPAKPF
CVLIDEAQFLNKKHVYDFARVVDELNVPVMAFGLKNDFRNELFEGSKYLLLLADKIEEIKTICWYCSKKATMVIRTIDGK
PVYEGEQLQIGGNETYIPVCRKHYFKPEI
>Mature_188_residues
AQLYFKYGTMNSGKSIEILKVAHNYEEQGKPVLLMTSSLDTRAGVGTVASRIGMKAEAVAIDEEMSVFDYVNSLPAKPFC
VLIDEAQFLNKKHVYDFARVVDELNVPVMAFGLKNDFRNELFEGSKYLLLLADKIEEIKTICWYCSKKATMVIRTIDGKP
VYEGEQLQIGGNETYIPVCRKHYFKPEI

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=187, Percent_Identity=48.6631016042781, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_LACLA (Q9CHX5)

Other databases:

- EMBL:   AE005176
- PIR:   A86699
- RefSeq:   NP_266749.1
- ProteinModelPortal:   Q9CHX5
- SMR:   Q9CHX5
- GeneID:   1114213
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L184871
- NMPDR:   fig|272623.1.peg.608
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- ProtClustDB:   PRK04296
- BioCyc:   LLAC272623:L184871-MONOMER
- BRENDA:   2.7.1.21
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21423; Mature: 21292

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFKYGTMNSGKSIEILKVAHNYEEQGKPVLLMTSSLDTRAGVGTVASRIGMKAEAV
CCEEEEEECCCCCCCCEEEEEEECCHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEE
AIDEEMSVFDYVNSLPAKPFCVLIDEAQFLNKKHVYDFARVVDELNVPVMAFGLKNDFRN
EECCHHHHHHHHHCCCCCCEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEEEECCHHHHH
ELFEGSKYLLLLADKIEEIKTICWYCSKKATMVIRTIDGKPVYEGEQLQIGGNETYIPVC
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFKPEI
HHCCCCCCC
>Mature Secondary Structure 
AQLYFKYGTMNSGKSIEILKVAHNYEEQGKPVLLMTSSLDTRAGVGTVASRIGMKAEAV
CEEEEEECCCCCCCCEEEEEEECCHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEE
AIDEEMSVFDYVNSLPAKPFCVLIDEAQFLNKKHVYDFARVVDELNVPVMAFGLKNDFRN
EECCHHHHHHHHHCCCCCCEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEEEECCHHHHH
ELFEGSKYLLLLADKIEEIKTICWYCSKKATMVIRTIDGKPVYEGEQLQIGGNETYIPVC
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFKPEI
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471