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The map label for this gene is glpT

Identifier: 15672537

GI number: 15672537

Start: 548432

End: 549733

Strand: Direct

Name: glpT

Synonym: L148346

Alternate gene names: 15672537

Gene position: 548432-549733 (Clockwise)

Preceding gene: 15672536

Following gene: 15672538

Centisome position: 23.18

GC content: 38.56

Gene sequence:

>1302_bases
TTGTATAAAATGTGGCAAACTCGAGTTTTAATTTCGACGGCATTCGTTTATATTGGTTATTATATTATTCGATTGATCTT
TACCGTTCAACAAAATGATATTTCCAAGGCTTATGGTTTTTCGATGGGACAAATTGGGACAATTCTCTCCATGTTTGGGA
TTGGCTATGGAATTTCAAAGCTTATTATGGGAACATTAGCTGACCGGGCCAATCCAAACCGTTATGTGGCAACAGGATTG
ATTGTGTCAGCGATTATCAATGCGCTTTATGGAACAACCCAAAGTTTTGGGATGATAGTCTTTCTGATGTTGCTTAACTC
GGTTATGCAAGGTATGGGAGCTGCGGCTTGTCAGCGTTTAGTCGGTTTATGGTTTGGCCGAAAAGCAAAAGGTTCGATTA
TGGCGCGTGGGACAGCATTTTCAATCTGGTCATCAGCTCATAATGCTGGAGCTTTCATGTGTGTGGCTGTCATTAATTTA
TCTGCTTTCTTTTTCGGCGCTTCGCTTCAATGGAGTTTTTGGACAGCATCAATTGTTTCGATTGTCATTGCTATTATCGT
TTTATTTCTGGGTTCTGACCGTCCAACGACGAAAGGATTACCGACAATTGAAGAATATTCTGGCGACAAAGTGGTCATTA
AAGACGGAGAAATTGTTGAAGGCGATGTTTCTAATGACAATGTTTTTAAAATATTTTTTGAATACATTGTCAAAAATAAA
CTCGTGTGGGCGGTCATTTTGACCTCATTGTCAATCTATGTCGTTCGTTATGGAATTATGAGTTGGATTCCAAACTATCT
GGTTAATATCAAAGGATTTGATAATTCAACAGCAAAATGGCTGACAGGAATTTTTGAACTTGCAGCTGTACCTGGGGTTA
TTATCATCGGATTTATCACTGATTTACTTAAAGGTCGTCGGGCCATTATGGTTTTGGTTTCATTGATTGCAATGCTTGCC
TGTCTGATTACTTATTTTGCAGCGACCAATCATACTTTGATTATTATTGTGTTATTAATTATGGGAACTTTCATTTATGC
TCCAGCAACAATTGTCGGGCTGATGGTCAATGAAGCTGTCCCAAAATTTGCCAATGGAATGTCAACGGGTACGATGGGGT
TCTGTCAGTACATTATTGGTGAAGTGACAGCAACTCTGGTTATTGGTTGGCTTGTTCAAGCATACGGCTGGTCAGCAGGA
AATATCATTGTTTATATTTTTGCCGGCATTGCCATTCTTGCTTCAATTTATATCTTGGTTCATCAAAATCGATTATATAA
GAAAATTGATGATGCAGGCTAA

Upstream 100 bases:

>100_bases
ATAATTAATTCATCAAAATGAAAGGGGATTCGAAATATTTGGATTCTTAAAACCCGCTCCAGATGCGGAGCAAAAAATAT
CAGAGGAAAAAGTTCCCCGA

Downstream 100 bases:

>100_bases
CTGACAAAATAAAAAATTACTGACAAACCTAGAAGGAAAAGCTAAATTTTTTATATTATATTTTGGCTCTACTGACAGCT
TTGTCAGTATTTTTTATTAA

Product: glycerol-3-phosphatase transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MYKMWQTRVLISTAFVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGISKLIMGTLADRANPNRYVATGL
IVSAIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKAKGSIMARGTAFSIWSSAHNAGAFMCVAVINL
SAFFFGASLQWSFWTASIVSIVIAIIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEIVEGDVSNDNVFKIFFEYIVKNK
LVWAVILTSLSIYVVRYGIMSWIPNYLVNIKGFDNSTAKWLTGIFELAAVPGVIIIGFITDLLKGRRAIMVLVSLIAMLA
CLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYIIGEVTATLVIGWLVQAYGWSAG
NIIVYIFAGIAILASIYILVHQNRLYKKIDDAG

Sequences:

>Translated_433_residues
MYKMWQTRVLISTAFVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGISKLIMGTLADRANPNRYVATGL
IVSAIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKAKGSIMARGTAFSIWSSAHNAGAFMCVAVINL
SAFFFGASLQWSFWTASIVSIVIAIIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEIVEGDVSNDNVFKIFFEYIVKNK
LVWAVILTSLSIYVVRYGIMSWIPNYLVNIKGFDNSTAKWLTGIFELAAVPGVIIIGFITDLLKGRRAIMVLVSLIAMLA
CLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYIIGEVTATLVIGWLVQAYGWSAG
NIIVYIFAGIAILASIYILVHQNRLYKKIDDAG
>Mature_433_residues
MYKMWQTRVLISTAFVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGISKLIMGTLADRANPNRYVATGL
IVSAIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKAKGSIMARGTAFSIWSSAHNAGAFMCVAVINL
SAFFFGASLQWSFWTASIVSIVIAIIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEIVEGDVSNDNVFKIFFEYIVKNK
LVWAVILTSLSIYVVRYGIMSWIPNYLVNIKGFDNSTAKWLTGIFELAAVPGVIIIGFITDLLKGRRAIMVLVSLIAMLA
CLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYIIGEVTATLVIGWLVQAYGWSAG
NIIVYIFAGIAILASIYILVHQNRLYKKIDDAG

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI46361976, Length=334, Percent_Identity=25.4491017964072, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI256219598, Length=394, Percent_Identity=19.7969543147208, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4503847, Length=394, Percent_Identity=19.7969543147208, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI256219483, Length=394, Percent_Identity=19.7969543147208, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788573, Length=435, Percent_Identity=28.9655172413793, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI2367259, Length=396, Percent_Identity=30.3030303030303, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082310, Length=432, Percent_Identity=27.3148148148148, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=23.4146341463415, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI2367379, Length=345, Percent_Identity=22.3188405797101, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI133901854, Length=349, Percent_Identity=24.3553008595989, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17542316, Length=412, Percent_Identity=25.2427184466019, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133901856, Length=349, Percent_Identity=24.0687679083095, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47356; Mature: 47356

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKMWQTRVLISTAFVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGISK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LIMGTLADRANPNRYVATGLIVSAIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
VGLWFGRKAKGSIMARGTAFSIWSSAHNAGAFMCVAVINLSAFFFGASLQWSFWTASIVS
HHHHCCCCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
IVIAIIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEIVEGDVSNDNVFKIFFEYIVKNK
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHH
LVWAVILTSLSIYVVRYGIMSWIPNYLVNIKGFDNSTAKWLTGIFELAAVPGVIIIGFIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
DLLKGRRAIMVLVSLIAMLACLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKFANGMSTGTMGFCQYIIGEVTATLVIGWLVQAYGWSAGNIIVYIFAGIAILASIYILV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
HQNRLYKKIDDAG
HCHHHHHHHCCCC
>Mature Secondary Structure
MYKMWQTRVLISTAFVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGISK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LIMGTLADRANPNRYVATGLIVSAIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
VGLWFGRKAKGSIMARGTAFSIWSSAHNAGAFMCVAVINLSAFFFGASLQWSFWTASIVS
HHHHCCCCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
IVIAIIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEIVEGDVSNDNVFKIFFEYIVKNK
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHH
LVWAVILTSLSIYVVRYGIMSWIPNYLVNIKGFDNSTAKWLTGIFELAAVPGVIIIGFIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
DLLKGRRAIMVLVSLIAMLACLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKFANGMSTGTMGFCQYIIGEVTATLVIGWLVQAYGWSAGNIIVYIFAGIAILASIYILV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
HQNRLYKKIDDAG
HCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 9714837 [H]