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The map label for this gene is glmM

Identifier: 15672406

GI number: 15672406

Start: 435077

End: 436435

Strand: Direct

Name: glmM

Synonym: L35068

Alternate gene names: 15672406

Gene position: 435077-436435 (Clockwise)

Preceding gene: 15672405

Following gene: 15672408

Centisome position: 18.39

GC content: 39.15

Gene sequence:

>1359_bases
ATGGGTAAATATTTCGGAACAGACGGTGTTCGCGGGGAAGCAAATGTTGAATTAACGCCGGAGATGGCTTTTAAACTTGG
TCGTTTTGGTGGCTATGTCCTTAGTCAACATGAATTAGGTACACCAAAAGTTTATGTTGGTCGCGATACACGAATTTCTG
GACAAATGCTTGCGAGCAGTTTGATTTCAGGACTTTTGTCTGTTGGGATTGAAGTTTATGATTTAGGAGTCATTGCAACA
CCAGGTGTAGCATATTTAGTTAAAAAAGATGGTGCCTCTGCTGGGGTCATGATTTCAGCCAGCCATAATCCAGCACTTGA
TAATGGAATTAAATTCTTTGGTGGTGATGGTTATAAATTAGAGGATGAAAAAGAACTTGAAATTGAAGCATTGATTGACG
CTGAAGAAGACACATTGCCACGTCCATCTGCTCAAGGCTTAGGAATGCTGCATGACTATATCGAAGGTGTTCGTAAATAT
CAAGCTTTCTTAAAAACAACAGCAGAAGGTAATTTTGAAGGCTATAAGGTTGTTCTTGATACCGCTAATGGTGCAGCTTA
TACTTCTGCTCGTGCCGTTTTTGCTGATTTAGAAGCGAATTTGACAGTTATTGGTGAAAATCCTGATGGACTCAATATCA
ATGTAAAAGTAGGCTCAACTCATCCTGAAGCGATGGCTAAAAAAGTTGTCGAAACAGGAAGTGACCTCGGACTTGCCTTT
GACGGTGATGCTGACCGCCTGATTGCCGTTGATGAAAATGGAGAAATTGTTGATGGCGATAAAATTATGTTTATCGTTGG
GAAATATCTTCTTGGACAAGGAAAATTGGCTCAAGATACGCTAGTAACAACTGTGATGTCTAATCTTGGATTTCATTTAG
CGCTTGAAGAAGCAGGGATTAATTCAGTGATTACAGCCGTTGGTGACCGTTATGTTGTTGAAGAAATGAAGAAAAATAAT
TACAACTTCGGTGGTGAACAATCGGGTCATATGATTTTCCTTGATTACAACACAACAGGAGATGGTCAACTTTCAGCCAT
TCAATTGTTGAAAGTAATGCGTGAAACTGGCAAATCTTTATCTGAATTAGCAAGTGAAGTTACGATTTATCCACAAAAAT
TAGTTAATGTTCGGGTAAAAGATAATGCAGCTAAAAAATCAGCAATGGATGTGCCAGCGATTCAAAAAGTAATTTCAGAA
ATGGAAACTTCAATGAATGGGAAAGGTCGTATTTTAGTTCGCCCTTCAGGAACTGAACCACTCTTGCGTGTCATGGCTGA
AGCGCCAACTCATGAAGAGGTCAATCATGTTGTAGATACCATTGTTGAAGTTGTTGAAGCAGAAATTGGTGTAAAATAA

Upstream 100 bases:

>100_bases
TGCTGATCCACAAGAAGTTGAAGTAACATTAACACCTGTAAAAATAAGTGGATAAATTTTCAGAGTCAAATAAAAATAAT
AAAAATGGAGACAAGAAAAA

Downstream 100 bases:

>100_bases
AGAAAAAAAGCAAGAACTGATTTTGTTCTTGCTTTTTATTATCAAGTAAAAACTCTCCTTATTGGGAGAGCTTTTTTATC
TTTTTTGTCGTCTGGCAAAT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MGKYFGTDGVRGEANVELTPEMAFKLGRFGGYVLSQHELGTPKVYVGRDTRISGQMLASSLISGLLSVGIEVYDLGVIAT
PGVAYLVKKDGASAGVMISASHNPALDNGIKFFGGDGYKLEDEKELEIEALIDAEEDTLPRPSAQGLGMLHDYIEGVRKY
QAFLKTTAEGNFEGYKVVLDTANGAAYTSARAVFADLEANLTVIGENPDGLNINVKVGSTHPEAMAKKVVETGSDLGLAF
DGDADRLIAVDENGEIVDGDKIMFIVGKYLLGQGKLAQDTLVTTVMSNLGFHLALEEAGINSVITAVGDRYVVEEMKKNN
YNFGGEQSGHMIFLDYNTTGDGQLSAIQLLKVMRETGKSLSELASEVTIYPQKLVNVRVKDNAAKKSAMDVPAIQKVISE
METSMNGKGRILVRPSGTEPLLRVMAEAPTHEEVNHVVDTIVEVVEAEIGVK

Sequences:

>Translated_452_residues
MGKYFGTDGVRGEANVELTPEMAFKLGRFGGYVLSQHELGTPKVYVGRDTRISGQMLASSLISGLLSVGIEVYDLGVIAT
PGVAYLVKKDGASAGVMISASHNPALDNGIKFFGGDGYKLEDEKELEIEALIDAEEDTLPRPSAQGLGMLHDYIEGVRKY
QAFLKTTAEGNFEGYKVVLDTANGAAYTSARAVFADLEANLTVIGENPDGLNINVKVGSTHPEAMAKKVVETGSDLGLAF
DGDADRLIAVDENGEIVDGDKIMFIVGKYLLGQGKLAQDTLVTTVMSNLGFHLALEEAGINSVITAVGDRYVVEEMKKNN
YNFGGEQSGHMIFLDYNTTGDGQLSAIQLLKVMRETGKSLSELASEVTIYPQKLVNVRVKDNAAKKSAMDVPAIQKVISE
METSMNGKGRILVRPSGTEPLLRVMAEAPTHEEVNHVVDTIVEVVEAEIGVK
>Mature_451_residues
GKYFGTDGVRGEANVELTPEMAFKLGRFGGYVLSQHELGTPKVYVGRDTRISGQMLASSLISGLLSVGIEVYDLGVIATP
GVAYLVKKDGASAGVMISASHNPALDNGIKFFGGDGYKLEDEKELEIEALIDAEEDTLPRPSAQGLGMLHDYIEGVRKYQ
AFLKTTAEGNFEGYKVVLDTANGAAYTSARAVFADLEANLTVIGENPDGLNINVKVGSTHPEAMAKKVVETGSDLGLAFD
GDADRLIAVDENGEIVDGDKIMFIVGKYLLGQGKLAQDTLVTTVMSNLGFHLALEEAGINSVITAVGDRYVVEEMKKNNY
NFGGEQSGHMIFLDYNTTGDGQLSAIQLLKVMRETGKSLSELASEVTIYPQKLVNVRVKDNAAKKSAMDVPAIQKVISEM
ETSMNGKGRILVRPSGTEPLLRVMAEAPTHEEVNHVVDTIVEVVEAEIGVK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=43.5267857142857, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI1788361, Length=453, Percent_Identity=25.1655629139073, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_LACLA (Q9CID9)

Other databases:

- EMBL:   AE005176
- PIR:   H86677
- RefSeq:   NP_266580.1
- ProteinModelPortal:   Q9CID9
- SMR:   Q9CID9
- GeneID:   1114036
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L35068
- NMPDR:   fig|272623.1.peg.433
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- ProtClustDB:   PRK14316
- BioCyc:   LLAC272623:L35068-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48473; Mature: 48342

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYFGTDGVRGEANVELTPEMAFKLGRFGGYVLSQHELGTPKVYVGRDTRISGQMLASS
CCCCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCHHHHHHHH
LISGLLSVGIEVYDLGVIATPGVAYLVKKDGASAGVMISASHNPALDNGIKFFGGDGYKL
HHHHHHHCCCEEEEECEEECCCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCC
EDEKELEIEALIDAEEDTLPRPSAQGLGMLHDYIEGVRKYQAFLKTTAEGNFEGYKVVLD
CCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TANGAAYTSARAVFADLEANLTVIGENPDGLNINVKVGSTHPEAMAKKVVETGSDLGLAF
CCCCCCHHHHHHEEEECCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEE
DGDADRLIAVDENGEIVDGDKIMFIVGKYLLGQGKLAQDTLVTTVMSNLGFHLALEEAGI
CCCCCEEEEECCCCCEECCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCC
NSVITAVGDRYVVEEMKKNNYNFGGEQSGHMIFLDYNTTGDGQLSAIQLLKVMRETGKSL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCHHH
SELASEVTIYPQKLVNVRVKDNAAKKSAMDVPAIQKVISEMETSMNGKGRILVRPSGTEP
HHHHHHHEECCHHHEEEEECCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHH
LLRVMAEAPTHEEVNHVVDTIVEVVEAEIGVK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKYFGTDGVRGEANVELTPEMAFKLGRFGGYVLSQHELGTPKVYVGRDTRISGQMLASS
CCCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCHHHHHHHH
LISGLLSVGIEVYDLGVIATPGVAYLVKKDGASAGVMISASHNPALDNGIKFFGGDGYKL
HHHHHHHCCCEEEEECEEECCCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCC
EDEKELEIEALIDAEEDTLPRPSAQGLGMLHDYIEGVRKYQAFLKTTAEGNFEGYKVVLD
CCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TANGAAYTSARAVFADLEANLTVIGENPDGLNINVKVGSTHPEAMAKKVVETGSDLGLAF
CCCCCCHHHHHHEEEECCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEE
DGDADRLIAVDENGEIVDGDKIMFIVGKYLLGQGKLAQDTLVTTVMSNLGFHLALEEAGI
CCCCCEEEEECCCCCEECCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCC
NSVITAVGDRYVVEEMKKNNYNFGGEQSGHMIFLDYNTTGDGQLSAIQLLKVMRETGKSL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCHHH
SELASEVTIYPQKLVNVRVKDNAAKKSAMDVPAIQKVISEMETSMNGKGRILVRPSGTEP
HHHHHHHEECCHHHEEEEECCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHH
LLRVMAEAPTHEEVNHVVDTIVEVVEAEIGVK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471