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The map label for this gene is nrdD

Identifier: 15672255

GI number: 15672255

Start: 270413

End: 272656

Strand: Direct

Name: nrdD

Synonym: L70400

Alternate gene names: 15672255

Gene position: 270413-272656 (Clockwise)

Preceding gene: 15672253

Following gene: 15672256

Centisome position: 11.43

GC content: 37.3

Gene sequence:

>2244_bases
ATGAAAAGTGAAGTAAAATATCAAGATGTAACACTAGAAGAAATTAATGTGATAAAGCGTGACGGACGCTCAGTGAAATT
TAACAGTGAGAAAATTTTTGATGCTTTGACTAAAGCGGCTAAAAAAGTCGAACTGACAGATATGTCGGTTCTTTCAGAAC
TTACTGACAGAGTAGTCAGTGAAATCTTTACTCGTTTTTCTGAAAATGTCAAAATTTATGAAATTCAATCGATTGTTGAG
CAAGAACTCCTTGAGTCTGGTGAAACTCAATTGGCTGAAGAATATATCTCTTATCGTGCTAACCGTGATTTGGCCCGTAC
CAAAGCAACGGATATCAATTTCACGATTGAAAAATTAATTAATCGCGACCAAACTGTCGTTAATGAAAATGCCAATAAAG
ATTCTAACGTTTTCAATACTCAACGTGATTTGACAGCTGGTGCGGTTTCCAAAGCAATTGGTTTGAAACTTCTTCCGCCA
CATGTGGCAAACGCTCACCAAAAGGGTGATATTCATTATCATGACCTTGATTATAGTCCATTTACTACAATGGCTAACTG
TTGTTTGATTGACTTTAAAAATATGTTTGAAAATGGTTTTAAACTTGGAAATGCGCAAGTAGATTCGCCAAAATCAATTC
AAACAGCAACTGCGCAAGCCAGTCAAATCATCGCTAATGTGGCTAGTTCACAATATGGTGGTTGTTCATTTGACCGTGCC
GATGAAGTATTGGCGCCTTACGCGAAATTAAATTATAAAAAACATTTAAAAGATGCACAAAAATGGATTGATGGTGCTGA
AAAACAAGAAGCTTATGCTCGTGAAAAAACAGCCAAAGATATCTATGATGCAATGCAATCTTTAGAATATGAAATTAATA
CTTTGTTTACTTCAAATGGTCAAACGCCTTTTGTAACGGTTGGTTTTGGTCTTGGAGACGATTGGTATGCGCGTGAAATT
CAAAAAGCAATTTTGAATGTCCGGATTGGTGGTTTAGGTTCAGAACACCGTACTGCCATTTTCCCTAAATTAATTTTCAC
ACTCAAACGTGGTCTTAACCTCGAAGTAGGGACACCAAACTATGACATCAAAGAACTTGCGCTTGAATGTTCAACAAAAC
GGATGTACCCTGATATTTTGAGCTATGATAAAATTGTTGAATTAACAGGTTCATTTAAAGCTTCAATGGGTTGTCGTTCA
TTCTTACAAGGCTGGAAAGATGAAAACGGGAATGACGTGACTGCTGGACGTAATAATCTTGGAGTTGTTACAGTTAACCT
TCCACGTATTGCTCTTGAAGCCGCTGGAAATAAAGAAAAATTCTGGGAAATCTTCAATGAAAGAATTGAAATTGCTCATG
ATGCCCTTGCTTTTCGTGTTGAACGTGCTAAAGAAGCACAACCTAAAAATGCACCTATTCTCTTTATGAATGGTGCATTG
GGACGCCTTGATGCCGAAGGTTCAGTTGATGAATTGTACAATAAAGAACGTGCAACTGTAAGTTTAGGTTACATTGGACT
TTATGAAGTGGCGACTACTTTTTATGGCCCAACTTGGGAAAATAATCCTGAAGCTAAAGCTTTTACAATTGAAATTGTGA
AACGAATGCATGAAGATTGTGAAGATTGGTCTAAAGCCTCTGGTTATCATTATTCTGTTTATTCAACACCGTCAGAAAGT
TTAACTGACCGTTTCTGCCGAATGGATAAAGAAAAATTCGGCTCAGTTGCAGATATTACTGACAAAGATTACTATACTAA
TTCTTTCCATTATGATGTGCGTAAAAATCCAACTCCATTTGAAAAATTAGAGTTTGAAAAAGACTATCCTGTTTATGCCA
ATGGTGGATTCATTCATTACTGTGAATATCCTGTTCTTCAACAAAATCCGAAAGCTCTTGAAGCAGTCTGGGACTTTGCC
TACGATCGTATTGGATATCTTGGAACAAATGCACCAATTGACCACTGCTATGCTTGTGGCTTTGAAGGAGATTTTGCGGC
AACGGAACGTGGATTTAAATGTCCACAATGTGGCAATGATGATCCTAAAACCTGTGACGTTGTCAAAAGAACTTGTGGAT
ATCTTGGAAATCCGCAAGCACGTCCAATGGTTCATGGTCGTCACAAAGAAATTTCATCACGTGTAAAACATATGAATGGT
TCTGTCGGAGCCTTGAACGATGGAAATTTGATTGATTCAGTCGAAGTTGACGAAGCGAAATCAAAATATTTTGCGGAGAA
ATAA

Upstream 100 bases:

>100_bases
AACACAAGATATTGTGTGTGTTTACATAATTTAACCTATATATTGTGTCATTTCCGAGAATTTGATAAAATAGATGATGT
AATTGAAGAGGATGGTTAAT

Downstream 100 bases:

>100_bases
GGAAGAAATAAGTATGAACAATCCAAAACCAGGAGAATGGAGAGCTGATGAACTCTCTCAAAATTATATTGCAGATTATA
AACCCTTCAATTTCGTTGAT

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MKSEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDMSVLSELTDRVVSEIFTRFSENVKIYEIQSIVE
QELLESGETQLAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYKKHLKDAQKWIDGAEKQEAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILNVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDENGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERIEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDAEGSVDELYNKERATVSLGYIGLYEVATTFYGPTWENNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFAATERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK

Sequences:

>Translated_747_residues
MKSEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDMSVLSELTDRVVSEIFTRFSENVKIYEIQSIVE
QELLESGETQLAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYKKHLKDAQKWIDGAEKQEAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILNVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDENGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERIEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDAEGSVDELYNKERATVSLGYIGLYEVATTFYGPTWENNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFAATERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK
>Mature_747_residues
MKSEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDMSVLSELTDRVVSEIFTRFSENVKIYEIQSIVE
QELLESGETQLAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYKKHLKDAQKWIDGAEKQEAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILNVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDENGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERIEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDAEGSVDELYNKERATVSLGYIGLYEVATTFYGPTWENNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFAATERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=713, Percent_Identity=52.0336605890603, Blast_Score=760, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 84176; Mature: 84176

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDMSVLSELTDRVVS
CCCCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIFTRFSENVKIYEIQSIVEQELLESGETQLAEEYISYRANRDLARTKATDINFTIEKLI
HHHHHHHCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHC
NRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPPHVANAHQKGDIHYHDLDYSP
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCHHCCCCCCCCEEEEECCCCC
FTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DEVLAPYAKLNYKKHLKDAQKWIDGAEKQEAYAREKTAKDIYDAMQSLEYEINTLFTSNG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
QTPFVTVGFGLGDDWYAREIQKAILNVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPN
CCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRSFLQGWKDENGNDVTAGRNNL
CCHHHHHHHHHHHHCCHHHHCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCE
GVVTVNLPRIALEAAGNKEKFWEIFNERIEIAHDALAFRVERAKEAQPKNAPILFMNGAL
EEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GRLDAEGSVDELYNKERATVSLGYIGLYEVATTFYGPTWENNPEAKAFTIEIVKRMHEDC
CCCCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EDWSKASGYHYSVYSTPSESLTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPF
HHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
EKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFAYDRIGYLGTNAPIDHCYACG
HHCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHEECC
FEGDFAATERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SVGALNDGNLIDSVEVDEAKSKYFAEK
CCCCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKSEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDMSVLSELTDRVVS
CCCCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIFTRFSENVKIYEIQSIVEQELLESGETQLAEEYISYRANRDLARTKATDINFTIEKLI
HHHHHHHCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHC
NRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPPHVANAHQKGDIHYHDLDYSP
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCHHCCCCCCCCEEEEECCCCC
FTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DEVLAPYAKLNYKKHLKDAQKWIDGAEKQEAYAREKTAKDIYDAMQSLEYEINTLFTSNG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
QTPFVTVGFGLGDDWYAREIQKAILNVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPN
CCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRSFLQGWKDENGNDVTAGRNNL
CCHHHHHHHHHHHHCCHHHHCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCE
GVVTVNLPRIALEAAGNKEKFWEIFNERIEIAHDALAFRVERAKEAQPKNAPILFMNGAL
EEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GRLDAEGSVDELYNKERATVSLGYIGLYEVATTFYGPTWENNPEAKAFTIEIVKRMHEDC
CCCCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EDWSKASGYHYSVYSTPSESLTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPF
HHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
EKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFAYDRIGYLGTNAPIDHCYACG
HHCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHEECC
FEGDFAATERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SVGALNDGNLIDSVEVDEAKSKYFAEK
CCCCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]