| Definition | Lactococcus lactis subsp. lactis Il1403, complete genome. |
|---|---|
| Accession | NC_002662 |
| Length | 2,365,589 |
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The map label for this gene is ycgG
Identifier: 15672250
GI number: 15672250
Start: 266240
End: 267085
Strand: Direct
Name: ycgG
Synonym: L66233
Alternate gene names: 15672250
Gene position: 266240-267085 (Clockwise)
Preceding gene: 15672249
Following gene: 15672251
Centisome position: 11.25
GC content: 38.65
Gene sequence:
>846_bases ATGACATTAACAGACACTTACACACTAAACAATGGCATTAAAATTCCAAAAGTTGGCTTTGGAACTTGGCAATCTGCGAG CGGAGAAGAAGCTTATAATGCGGTAAAAGCAGCACTTGAAGCAGGATATCGTCATATTGATACAGCGGCAGTTTATAAAA ATGAAGAATCAGTCGGTCAAGCAATTGCTGATTCAGGAATTCCCCGTGAGGAACTTTTCGTTACAACAAAACTTTGGGGT GTAGGAACAACAGAGGACGCTGCGAAAGCCTTGGATGAATCCTTGAAAAAATTGGGACTTGATTATGTTGATTTGTACCT CATTCATTGGCCAAATCCTAAAGCATTCCGCCCTGATTTTGAAACACGTAATCTTGCAGTTTGGAAAGCCATGGAAGCAG GCGTAAAAGCTGGTAAAATCCGTGCAATTGGTGTTTCAAACTTCCACCCACGTCACCTAAAACCATTGTTGAAATTTGCT GAAATTAAACCAGCAGTTAACCAAATTATGGTCAACCCAAGTGATCAACAAGAAGAAATTGTAAGCTTTAATGTTGACAA CAATATCTTGACTGAGGCTTACAGCCCACTTGGAACAGGTAAAATCTTTGAAGTTCCAGAACTTGCAGACTTGGCAAGTA AATACAACAAGAGTATTGCTCAAGTGGTATTGCGTTGGTCTCTTCACAAAGGATATTTACCACTTCCTAAATCAGTAACC CCTGCAAGAATTAAAGAAAATGCAGAAATCTTTGATTTTGATTTAAGTATTGAAGATATTGCTTTTATTGACAGCCTTCA TGGAAAAGCTGGTTTGGCTAAAAACCCTGATGAAGTTGATTTCTAA
Upstream 100 bases:
>100_bases GAGTTAGAACTATGGTTTCCAATTGAAAGAATATAAAAGTCCAAATAGTTTCATTGATGACGAGTTGTTGTATTTCAAAA ATTACTAAGTAGAAAAAATC
Downstream 100 bases:
>100_bases AGAATAATTATGAACATATTTTACTGACAGATTGTTTAGATCTCTTAAAAGACAGCAGAGAATTTGGTCAGTAATTTAAA AAAGGTCTGTCAGTAAAATT
Product: oxidoreductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 281; Mature: 280
Protein sequence:
>281_residues MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAVYKNEESVGQAIADSGIPREELFVTTKLWG VGTTEDAAKALDESLKKLGLDYVDLYLIHWPNPKAFRPDFETRNLAVWKAMEAGVKAGKIRAIGVSNFHPRHLKPLLKFA EIKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVPELADLASKYNKSIAQVVLRWSLHKGYLPLPKSVT PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF
Sequences:
>Translated_281_residues MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAVYKNEESVGQAIADSGIPREELFVTTKLWG VGTTEDAAKALDESLKKLGLDYVDLYLIHWPNPKAFRPDFETRNLAVWKAMEAGVKAGKIRAIGVSNFHPRHLKPLLKFA EIKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVPELADLASKYNKSIAQVVLRWSLHKGYLPLPKSVT PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF >Mature_280_residues TLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAVYKNEESVGQAIADSGIPREELFVTTKLWGV GTTEDAAKALDESLKKLGLDYVDLYLIHWPNPKAFRPDFETRNLAVWKAMEAGVKAGKIRAIGVSNFHPRHLKPLLKFAE IKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVPELADLASKYNKSIAQVVLRWSLHKGYLPLPKSVTP ARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=287, Percent_Identity=39.0243902439024, Blast_Score=200, Evalue=1e-51, Organism=Homo sapiens, GI5174391, Length=287, Percent_Identity=39.0243902439024, Blast_Score=200, Evalue=1e-51, Organism=Homo sapiens, GI223468663, Length=291, Percent_Identity=38.4879725085911, Blast_Score=187, Evalue=1e-47, Organism=Homo sapiens, GI45446745, Length=296, Percent_Identity=39.1891891891892, Blast_Score=181, Evalue=9e-46, Organism=Homo sapiens, GI4503285, Length=296, Percent_Identity=39.1891891891892, Blast_Score=181, Evalue=9e-46, Organism=Homo sapiens, GI310109920, Length=296, Percent_Identity=38.8513513513513, Blast_Score=181, Evalue=9e-46, Organism=Homo sapiens, GI24497585, Length=296, Percent_Identity=38.5135135135135, Blast_Score=180, Evalue=1e-45, Organism=Homo sapiens, GI5453543, Length=296, Percent_Identity=38.5135135135135, Blast_Score=179, Evalue=2e-45, Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=41.9243986254296, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI5174695, Length=297, Percent_Identity=37.7104377104377, Blast_Score=176, Evalue=2e-44, Organism=Homo sapiens, GI310109922, Length=282, Percent_Identity=39.0070921985816, Blast_Score=176, Evalue=2e-44, Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=37.6271186440678, Blast_Score=176, Evalue=3e-44, Organism=Homo sapiens, GI93277124, Length=309, Percent_Identity=34.6278317152104, Blast_Score=169, Evalue=4e-42, Organism=Homo sapiens, GI300116273, Length=280, Percent_Identity=37.1428571428571, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI291291012, Length=266, Percent_Identity=36.4661654135338, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI300116271, Length=278, Percent_Identity=33.4532374100719, Blast_Score=135, Evalue=5e-32, Organism=Homo sapiens, GI207028673, Length=110, Percent_Identity=50.9090909090909, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI310109926, Length=110, Percent_Identity=50, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI310109924, Length=153, Percent_Identity=34.640522875817, Blast_Score=87, Evalue=2e-17, Organism=Escherichia coli, GI87082198, Length=272, Percent_Identity=44.1176470588235, Blast_Score=224, Evalue=5e-60, Organism=Escherichia coli, GI1786400, Length=256, Percent_Identity=37.5, Blast_Score=155, Evalue=4e-39, Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=30.8823529411765, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.4150943396226, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI87081735, Length=206, Percent_Identity=29.126213592233, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI48994888, Length=259, Percent_Identity=26.6409266409266, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787674, Length=293, Percent_Identity=24.2320819112628, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI71998625, Length=266, Percent_Identity=38.7218045112782, Blast_Score=191, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17537077, Length=293, Percent_Identity=39.9317406143345, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17564128, Length=300, Percent_Identity=37.6666666666667, Blast_Score=185, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17537075, Length=293, Percent_Identity=39.9317406143345, Blast_Score=183, Evalue=8e-47, Organism=Caenorhabditis elegans, GI17550248, Length=293, Percent_Identity=40.9556313993174, Blast_Score=173, Evalue=1e-43, Organism=Caenorhabditis elegans, GI17561298, Length=270, Percent_Identity=37.4074074074074, Blast_Score=171, Evalue=5e-43, Organism=Caenorhabditis elegans, GI17566692, Length=289, Percent_Identity=34.9480968858132, Blast_Score=165, Evalue=3e-41, Organism=Caenorhabditis elegans, GI17537079, Length=302, Percent_Identity=34.7682119205298, Blast_Score=161, Evalue=4e-40, Organism=Caenorhabditis elegans, GI17552492, Length=265, Percent_Identity=34.3396226415094, Blast_Score=156, Evalue=1e-38, Organism=Caenorhabditis elegans, GI17538386, Length=281, Percent_Identity=33.8078291814947, Blast_Score=155, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17562292, Length=254, Percent_Identity=33.8582677165354, Blast_Score=154, Evalue=4e-38, Organism=Caenorhabditis elegans, GI17561300, Length=251, Percent_Identity=34.6613545816733, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17550246, Length=75, Percent_Identity=50.6666666666667, Blast_Score=70, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6324694, Length=292, Percent_Identity=44.8630136986301, Blast_Score=228, Evalue=7e-61, Organism=Saccharomyces cerevisiae, GI6320576, Length=288, Percent_Identity=43.0555555555556, Blast_Score=219, Evalue=3e-58, Organism=Saccharomyces cerevisiae, GI6322556, Length=271, Percent_Identity=38.0073800738007, Blast_Score=175, Evalue=7e-45, Organism=Saccharomyces cerevisiae, GI6319625, Length=274, Percent_Identity=37.956204379562, Blast_Score=166, Evalue=4e-42, Organism=Saccharomyces cerevisiae, GI6320079, Length=297, Percent_Identity=38.047138047138, Blast_Score=159, Evalue=7e-40, Organism=Saccharomyces cerevisiae, GI6321896, Length=310, Percent_Identity=31.9354838709677, Blast_Score=135, Evalue=6e-33, Organism=Drosophila melanogaster, GI24644950, Length=301, Percent_Identity=41.8604651162791, Blast_Score=209, Evalue=1e-54, Organism=Drosophila melanogaster, GI24657054, Length=284, Percent_Identity=43.3098591549296, Blast_Score=206, Evalue=2e-53, Organism=Drosophila melanogaster, GI221378297, Length=321, Percent_Identity=38.6292834890966, Blast_Score=201, Evalue=6e-52, Organism=Drosophila melanogaster, GI24663317, Length=294, Percent_Identity=39.1156462585034, Blast_Score=197, Evalue=6e-51, Organism=Drosophila melanogaster, GI20129731, Length=288, Percent_Identity=40.2777777777778, Blast_Score=195, Evalue=3e-50, Organism=Drosophila melanogaster, GI21356425, Length=282, Percent_Identity=40.0709219858156, Blast_Score=193, Evalue=1e-49, Organism=Drosophila melanogaster, GI24662789, Length=293, Percent_Identity=36.1774744027304, Blast_Score=181, Evalue=7e-46, Organism=Drosophila melanogaster, GI45553081, Length=286, Percent_Identity=38.4615384615385, Blast_Score=174, Evalue=4e-44, Organism=Drosophila melanogaster, GI24662781, Length=275, Percent_Identity=38.5454545454545, Blast_Score=157, Evalue=7e-39, Organism=Drosophila melanogaster, GI24662785, Length=273, Percent_Identity=38.0952380952381, Blast_Score=151, Evalue=5e-37, Organism=Drosophila melanogaster, GI281366140, Length=244, Percent_Identity=37.2950819672131, Blast_Score=150, Evalue=9e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 31060; Mature: 30928
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 0.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAVYKNEESVGQ CCCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH AIADSGIPREELFVTTKLWGVGTTEDAAKALDESLKKLGLDYVDLYLIHWPNPKAFRPDF HHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC ETRNLAVWKAMEAGVKAGKIRAIGVSNFHPRHLKPLLKFAEIKPAVNQIMVNPSDQQEEI CCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHEEECCCCCCCCE VSFNVDNNILTEAYSPLGTGKIFEVPELADLASKYNKSIAQVVLRWSLHKGYLPLPKSVT EEEECCCCHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF HHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure TLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAVYKNEESVGQ CCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH AIADSGIPREELFVTTKLWGVGTTEDAAKALDESLKKLGLDYVDLYLIHWPNPKAFRPDF HHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC ETRNLAVWKAMEAGVKAGKIRAIGVSNFHPRHLKPLLKFAEIKPAVNQIMVNPSDQQEEI CCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHEEECCCCCCCCE VSFNVDNNILTEAYSPLGTGKIFEVPELADLASKYNKSIAQVVLRWSLHKGYLPLPKSVT EEEECCCCHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF HHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA