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The map label for this gene is cdsA

Identifier: 13358075

GI number: 13358075

Start: 633118

End: 634254

Strand: Reverse

Name: cdsA

Synonym: UU511

Alternate gene names: 13358075

Gene position: 634254-633118 (Counterclockwise)

Preceding gene: 13358076

Following gene: 13358072

Centisome position: 84.37

GC content: 22.43

Gene sequence:

>1137_bases
ATGATTAGTGTCAATAAAATCAATGAAAAAACAAAAAACACTTTTTTTAAACGGTTTTATTCATCGATTTTTATTTTTTT
ATACTTATTAATTTATTTTGTTTTAGCATTATTAGCAGATCGTAATTATAATTGAACACCTTTAATTAATAATTTATATA
TTCAACAAGGGATTGCAATTGTTTTATTAATATGATTATTACCATTAATATGTATTGGTTCGTATGAAATGAATAAAGTC
ATTTTTGATAATAATAAGATAACATTAATCATCTTAACAATTGTTTTTAATATTTGCATTTATACTACAACGATTTCTTA
TTTTATATATCAATATGAGTTTTTAAATATTAAATACCTTTTAACTATAAATTACCATTACGTCATCAAACTATTTGGCG
CATGTTTAGGATGCTCGTATTTTGTTACATTAGTTATTTTATTTTTCTTTTTAGCATTTCTAAAAAAAATTAATTTCAAA
AATTGTTTATACACAATTTTAATTTTTAGTTTTTTAAGTGGTTTTTTTATAGGATTACTTTATTTTACTTTTATTAGAAG
TTGAATTACTTCATTATTGCTAATGATGATTGTTTTTTTAAGTGATACATTTGCATATGTTGGTGGTGTTTTATTTGGTA
AAACAAAATTAGCACCAAAAATAAGTCCTAACAAAACAGTTGAAGGATTAATTTTTGGTTTAGTAATTGCAACAATTGTT
ATTATGTTAATAATTTTTGGTTTGTCATATGTGCCAATTAAACCTAAAAACGGCATAGTGTTAAAATCACAAAATGTTTT
ATATAATATTTTTGGTTTAGATTTTTCTAGTTCAAATGAAAAAAATCTTACATTGCATAAACAAGCATTATGATGAATTT
GCACAATAGTTGCTTTTTTGTTTTTGAGTTTAATAAGCACTAGTGGGGACTTAGTATTTAGTGCGATTAAACGTAATTAT
CATACCAAAGATTATAGTAATTTAATTCCTGGCCATGGTGGATTATTAGATCGTATAGATTCACATTCATTTGTAATATC
AATCATGTTCATTTTTACACTTCTTATTACAGGCAGTTTACAAGATGAAAATTTATTTCCTAACATTCAAAAATTTTTTA
TTCAATTAATTGTATAA

Upstream 100 bases:

>100_bases
CAAACAGAATTAGATAATTTAACAAAAGAATTAAATAAGGAAATCGAAACAGTTGTAAGTCATAAAGAAAAAGACATAAT
GACTGTTTAATTAATTAAAA

Downstream 100 bases:

>100_bases
TTTGAAATTATTAATTATAGATTCAATTAATGGTTGAGTATTAGTGTATATACTAATATCAATCATTTTTTGATCTGTTT
TTAAACTAAGAAAGATTTTT

Product: CDP-diglyceride synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MISVNKINEKTKNTFFKRFYSSIFIFLYLLIYFVLALLADRNYNWTPLINNLYIQQGIAIVLLIWLLPLICIGSYEMNKV
IFDNNKITLIILTIVFNICIYTTTISYFIYQYEFLNIKYLLTINYHYVIKLFGACLGCSYFVTLVILFFFLAFLKKINFK
NCLYTILIFSFLSGFFIGLLYFTFIRSWITSLLLMMIVFLSDTFAYVGGVLFGKTKLAPKISPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNGIVLKSQNVLYNIFGLDFSSSNEKNLTLHKQALWWICTIVAFLFLSLISTSGDLVFSAIKRNY
HTKDYSNLIPGHGGLLDRIDSHSFVISIMFIFTLLITGSLQDENLFPNIQKFFIQLIV

Sequences:

>Translated_378_residues
MISVNKINEKTKNTFFKRFYSSIFIFLYLLIYFVLALLADRNYN*TPLINNLYIQQGIAIVLLI*LLPLICIGSYEMNKV
IFDNNKITLIILTIVFNICIYTTTISYFIYQYEFLNIKYLLTINYHYVIKLFGACLGCSYFVTLVILFFFLAFLKKINFK
NCLYTILIFSFLSGFFIGLLYFTFIRS*ITSLLLMMIVFLSDTFAYVGGVLFGKTKLAPKISPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNGIVLKSQNVLYNIFGLDFSSSNEKNLTLHKQAL**ICTIVAFLFLSLISTSGDLVFSAIKRNY
HTKDYSNLIPGHGGLLDRIDSHSFVISIMFIFTLLITGSLQDENLFPNIQKFFIQLIV
>Mature_378_residues
MISVNKINEKTKNTFFKRFYSSIFIFLYLLIYFVLALLADRNYN*TPLINNLYIQQGIAIVLLI*LLPLICIGSYEMNKV
IFDNNKITLIILTIVFNICIYTTTISYFIYQYEFLNIKYLLTINYHYVIKLFGACLGCSYFVTLVILFFFLAFLKKINFK
NCLYTILIFSFLSGFFIGLLYFTFIRS*ITSLLLMMIVFLSDTFAYVGGVLFGKTKLAPKISPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNGIVLKSQNVLYNIFGLDFSSSNEKNLTLHKQAL**ICTIVAFLFLSLISTSGDLVFSAIKRNY
HTKDYSNLIPGHGGLLDRIDSHSFVISIMFIFTLLITGSLQDENLFPNIQKFFIQLIV

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Homo sapiens, GI20143480, Length=181, Percent_Identity=32.5966850828729, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319503, Length=168, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 42592; Mature: 42592

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNKINEKTKNTFFKRFYSSIFIFLYLLIYFVLALLADRNYNTPLINNLYIQQGIAIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LLILLPLICIGSYEMNKVIFDNNKITLIILTIVFNICIYTTTISYFIYQYEFLNIKYLLT
HHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
INYHYVIKLFGACLGCSYFVTLVILFFFLAFLKKINFKNCLYTILIFSFLSGFFIGLLYF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TFIRSITSLLLMMIVFLSDTFAYVGGVLFGKTKLAPKISPNKTVEGLIFGLVIATIVIML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IIFGLSYVPIKPKNGIVLKSQNVLYNIFGLDFSSSNEKNLTLHKQALICTIVAFLFLSLI
HHHCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
STSGDLVFSAIKRNYHTKDYSNLIPGHGGLLDRIDSHSFVISIMFIFTLLITGSLQDENL
HCCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
FPNIQKFFIQLIV
CCHHHHHHHHHCC
>Mature Secondary Structure
MISVNKINEKTKNTFFKRFYSSIFIFLYLLIYFVLALLADRNYNTPLINNLYIQQGIAIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LLILLPLICIGSYEMNKVIFDNNKITLIILTIVFNICIYTTTISYFIYQYEFLNIKYLLT
HHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
INYHYVIKLFGACLGCSYFVTLVILFFFLAFLKKINFKNCLYTILIFSFLSGFFIGLLYF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TFIRSITSLLLMMIVFLSDTFAYVGGVLFGKTKLAPKISPNKTVEGLIFGLVIATIVIML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IIFGLSYVPIKPKNGIVLKSQNVLYNIFGLDFSSSNEKNLTLHKQALICTIVAFLFLSLI
HHHCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
STSGDLVFSAIKRNYHTKDYSNLIPGHGGLLDRIDSHSFVISIMFIFTLLITGSLQDENL
HCCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
FPNIQKFFIQLIV
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]