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The map label for this gene is pheS

Identifier: 13358021

GI number: 13358021

Start: 522503

End: 523504

Strand: Reverse

Name: pheS

Synonym: UU458

Alternate gene names: 13358021

Gene position: 523504-522503 (Counterclockwise)

Preceding gene: 13358022

Following gene: 13358020

Centisome position: 69.64

GC content: 25.35

Gene sequence:

>1002_bases
ATGGATGTTATTAATCTAATTAAAAATTTAAAACAAATTTTACGAACAGCAAATAATGAACGTCATTTGATTGAATTAAA
AAATATTTTTGTTAAACAACATTTATTACCACTATATGATGAATTAAAAAAAAGCGCTAATAAAAAAGAAATGGGTTTAT
TAATTAATAATTTCAAACAACAAATTGAATTTGTTACTGATCAAATTTTAAAAGAATTAAATGATAAAGATGATCAAGTT
GATTTAAAAAAATGAACAAATAAGACTTTGTTTGCTCCTTTTATTAATAATGGGCATCATCATATTCTCAATAGTATTAT
TGATGATATTGCATCTTTTTTTAAAAAATTAAATTTTGAAATTGTAAGTGGTTCAGAAGTTGTTTCACCTATTTATAATT
TTGATCATTTAAATATTGATGAAAATCATCCAGCAAGAGCAAGTGCTGATTCTTTTTTTATTAATTCAATTAAAATGTTA
CGTACGCATTGCACAACTACAACCGCACAATTTTTAGAAAATAACGTAAACAAGGACATTAGAATTATGTCTTTTGGTAA
TGTTTATCGAAAAGATGATGATGATGCAACACATAGCCACCAATTCAATCAAGTTGATTTTGTATGAGTTAAAGAAGGTT
TAACTGTTGCTAATTTAAAGTGATTAATTGACAGTTTGATTAAATATTTATTTGGTCAAAATTTAAAAACACGTTATCGT
TTAAGTTTTTTTCCGTTTACTGAGCCTTCGTTTGAAGTTGATGTTCAATGTTTTAAATGCGATTTAAAAGGGTGTGCAGT
TTGCAAAAAAAGTACATGAATTGAAATTATGGGAACTGGAATGCTACATGAAAATGTTCTAAAAGCTGCGAATATTAACG
ATATTAGAACAGGGATGGCTTTTGGTGTGGGTATTGATCGAATTGCAATGTTAAAATATGAAATTGATGATATTCGTTAT
TTATATTCAAATAATTTTAAATTTAATGCCCAAATTAAATAA

Upstream 100 bases:

>100_bases
TAAGAATTGGTTTCGTAATTTTCAAAAAAATAATAAAGAAGATCAAAAAGTGATTAAAGATCAACAAGAAGATACTAAAA
AAGAAAGCGAGTAAGTGTTC

Downstream 100 bases:

>100_bases
ATTCCTAAATTTAATGAAAGAGTAAAAAAAGATGATTTTAAGTTTAAATTTATTACATAAGATTAGTCCAAAACTAAAAA
AGATTCCTTTAAATGAATTA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQQIEFVTDQILKELNDKDDQV
DLKKWTNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEIVSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKML
RTHCTTTTAQFLENNVNKDIRIMSFGNVYRKDDDDATHSHQFNQVDFVWVKEGLTVANLKWLIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKSTWIEIMGTGMLHENVLKAANINDIRTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK

Sequences:

>Translated_333_residues
MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQQIEFVTDQILKELNDKDDQV
DLKK*TNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEIVSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKML
RTHCTTTTAQFLENNVNKDIRIMSFGNVYRKDDDDATHSHQFNQVDFV*VKEGLTVANLK*LIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKST*IEIMGTGMLHENVLKAANINDIRTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK
>Mature_333_residues
MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQQIEFVTDQILKELNDKDDQV
DLKK*TNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEIVSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKML
RTHCTTTTAQFLENNVNKDIRIMSFGNVYRKDDDDATHSHQFNQVDFV*VKEGLTVANLK*LIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKST*IEIMGTGMLHENVLKAANINDIRTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=306, Percent_Identity=26.797385620915, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1788007, Length=287, Percent_Identity=33.1010452961672, Blast_Score=167, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32566635, Length=249, Percent_Identity=26.5060240963855, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325304, Length=99, Percent_Identity=37.3737373737374, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137424, Length=252, Percent_Identity=28.1746031746032, Blast_Score=104, Evalue=8e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR022911
- InterPro:   IPR002319 [H]

Pfam domain/function: PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37896; Mature: 37896

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQ
CCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIEFVTDQILKELNDKDDQVDLKKTNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEI
HHHHHHHHHHHHHCCCCCCEEHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
VSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKMLRTHCTTTTAQFLENNVNKDIR
ECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IMSFGNVYRKDDDDATHSHQFNQVDFVVKEGLTVANLKLIDSLIKYLFGQNLKTRYRLSF
EEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
FPFTEPSFEVDVQCFKCDLKGCAVCKKSTIEIMGTGMLHENVLKAANINDIRTGMAFGVG
ECCCCCCCEEEEEEEEECCCHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCC
IDRIAMLKYEIDDIRYLYSNNFKFNAQIK
HHHHHHEEEHHHHHHHEECCCEEEEEEEC
>Mature Secondary Structure
MDVINLIKNLKQILRTANNERHLIELKNIFVKQHLLPLYDELKKSANKKEMGLLINNFKQ
CCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIEFVTDQILKELNDKDDQVDLKKTNKTLFAPFINNGHHHILNSIIDDIASFFKKLNFEI
HHHHHHHHHHHHHCCCCCCEEHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
VSGSEVVSPIYNFDHLNIDENHPARASADSFFINSIKMLRTHCTTTTAQFLENNVNKDIR
ECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IMSFGNVYRKDDDDATHSHQFNQVDFVVKEGLTVANLKLIDSLIKYLFGQNLKTRYRLSF
EEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
FPFTEPSFEVDVQCFKCDLKGCAVCKKSTIEIMGTGMLHENVLKAANINDIRTGMAFGVG
ECCCCCCCEEEEEEEEECCCHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCC
IDRIAMLKYEIDDIRYLYSNNFKFNAQIK
HHHHHHEEEHHHHHHHEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA