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The map label for this gene is ureC

Identifier: 13357995

GI number: 13357995

Start: 493594

End: 495390

Strand: Reverse

Name: ureC

Synonym: UU432

Alternate gene names: 13357995

Gene position: 495390-493594 (Counterclockwise)

Preceding gene: 13357996

Following gene: 13357994

Centisome position: 65.9

GC content: 34.06

Gene sequence:

>1797_bases
ATGTTTAAAATTTCAAGAAAAAATTATTCAGATTTATACGGTATTACAACTGGTGATAGCGTTAGATTAGGAGATACAAA
TCTTTGAGTTAAAGTTGAAAAAGACTTAACTACTTATGGTGAAGAATCTGTTTTTGGTGGTGGAAAAACCCTACGTGAAG
GTATGGGAATGAATTCTACTATGAAGTTAGATGATAAATTAGGTAATGCTGAAGTAATGGATTTAGTTATTACAAATGCA
CTAATTGTTGATTATACAGGTATTTATAAAGCAGATATTGGTATTAAAAATGGAAAAATTGCTGCGATTGGTAAATCTGG
AAATCCACATTTAACAGATAATGTTGATATGATTGTGGGTATCTCAACTGAAATTTCAGCTGGTGAGGGTAAAATTTATA
CAGCTGGTGGTTTAGATACTCACGTTCACTGACTAGAACCAGAAATAGTTCCTGTTGCATTAGATGGTGGTATTACAACT
GTTATTGCTGGTGGTACAGGTATGAATGATGGTACAAAAGCCACAACTGTTTCACCTGGTAAATTTTGAGTTAAATCAGC
TTTACAAGCAGCTGATGGATTATCAATTAATGCCGGTTTTTTAGCTAAAGGTCAAGGTATGGAAGATCCAATTTTTGAGC
AAATTGCTGCTGGAGCTTGTGGACTTAAAATCCATGAAGACTGAGGGGCAACAGGAAATGCGATTGATTTAGCATTAACA
GTTGCTGATAAAACTGATGTAGCTGTTGCTATTCATACAGATACATTAAATGAAGCTGGATTTGTAGAACATACAATTGC
AGCTATGAAAGGGCGAACAATTCATGCTTATCATACAGAAGGTGCTGGTGGAGGGCATGCTCCAGATATTCTAGAAACTG
TTAAATATGCCCATATTTTACCAGCTTCTACAAACCCAACAATTCCTTATACAGTAAATACAATTGCTGAACATTTAGAT
ATGTTAATGGTATGTCACCACTTAAATCCTAAGGTTCCAGAAGATGTTGCTTTTGCTGATTCACGTATTCGTAGCCAAAC
AATTGCAGCTGAAGACTTATTGCACGATATGGGTGCAATTTCAATTATGTCATCAGATACATTAGCTATGGGACGTATTG
GCGAAGTTGCAACTCGTACATGACAAATGGCTCACAAAATGAAAGCACAATTTGGATCATTAAAAGGTGATAGTGAATTC
AGTGATAACAATCGTGTAAAACGTTATATTTCTAAATATACAATTAACCCAGCTATTGCACATGGTGTTGATTCTTATAT
TGGTTCACTAGAAGTTGGTAAATTAGCTGATATTGTTGCTTGAGAACCTAAATTCTTTGGTGCAAAACCTTATTATGTTG
TAAAAATGGGTGTAATCGCTCGTTGTGTAGCAGGTGATCCAAATGCTTCAATTCCAACATGCGAACCTGTAATTATGCGT
GACCAATTTGGAACTTATGGACGTTTGTTAACTAATACATCAGTAAGTTTTGTTTCAAAAATTGGGTTAGAAAATGGCAT
TAAAGAGGAATATAAATTAGAAAAAGAATTATTACCAGTTAAAAATTGCCGTTCAGTAAATAAAAAGAGTATGAAATGAA
ACTCTGCGACTCCAAATTTAGAAGTTGATCCGCAAACTTTTGATGCTGCTGTTGATTTTAATGATTTAGAAAATTGACTA
GAACAATCAGCTTCTGAATTAGCTAAAAAATTAAAAAAGACTTCAAGTGGCAAATATATACTTGATGCTGAACCTTTAAC
AGAAGCGCCATTAGCACAAAGATATTTCTTATTTTAA

Upstream 100 bases:

>100_bases
AACACGCGAAGTTTGAGGTGTAAATGGCTTAGTTAATGGAAAACTTAAAAAATAAAACTCTATTTTACAAGTTTCTACTA
TAGATAAAAAGGGGAACATT

Downstream 100 bases:

>100_bases
TTGTCAAACTAAAATATTATATTAATTTATTTTCGTTACATTTTAAAAAAGCGAGGTAATAATCTTGACTGTATTTAAAG
AAATTTTAGATAATATTGCT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNLWVKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LIVDYTGIYKADIGIKNGKIAAIGKSGNPHLTDNVDMIVGISTEISAGEGKIYTAGGLDTHVHWLEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKFWVKSALQAADGLSINAGFLAKGQGMEDPIFEQIAAGACGLKIHEDWGATGNAIDLALT
VADKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILETVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVATRTWQMAHKMKAQFGSLKGDSEF
SDNNRVKRYISKYTINPAIAHGVDSYIGSLEVGKLADIVAWEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRLLTNTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSVNKKSMKWNSATPNLEVDPQTFDAAVDFNDLENWL
EQSASELAKKLKKTSSGKYILDAEPLTEAPLAQRYFLF

Sequences:

>Translated_598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNL*VKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LIVDYTGIYKADIGIKNGKIAAIGKSGNPHLTDNVDMIVGISTEISAGEGKIYTAGGLDTHVH*LEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKF*VKSALQAADGLSINAGFLAKGQGMEDPIFEQIAAGACGLKIHED*GATGNAIDLALT
VADKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILETVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVATRT*QMAHKMKAQFGSLKGDSEF
SDNNRVKRYISKYTINPAIAHGVDSYIGSLEVGKLADIVA*EPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRLLTNTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSVNKKSMK*NSATPNLEVDPQTFDAAVDFNDLEN*L
EQSASELAKKLKKTSSGKYILDAEPLTEAPLAQRYFLF
>Mature_598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNL*VKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LIVDYTGIYKADIGIKNGKIAAIGKSGNPHLTDNVDMIVGISTEISAGEGKIYTAGGLDTHVH*LEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKF*VKSALQAADGLSINAGFLAKGQGMEDPIFEQIAAGACGLKIHED*GATGNAIDLALT
VADKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILETVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVATRT*QMAHKMKAQFGSLKGDSEF
SDNNRVKRYISKYTINPAIAHGVDSYIGSLEVGKLADIVA*EPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRLLTNTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSVNKKSMK*NSATPNLEVDPQTFDAAVDFNDLEN*L
EQSASELAKKLKKTSSGKYILDAEPLTEAPLAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 62911; Mature: 62911

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKISRKNYSDLYGITTGDSVRLGDTNLVKVEKDLTTYGEESVFGGGKTLREGMGMNSTM
CCEECCCCCCCEEEECCCCEEEECCCCEEEEEHHHHHCCCCCCCCCCHHHHHCCCCCCEE
KLDDKLGNAEVMDLVITNALIVDYTGIYKADIGIKNGKIAAIGKSGNPHLTDNVDMIVGI
EECCCCCCHHHHHHHHHCEEEEEECCEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
STEISAGEGKIYTAGGLDTHVHLEPEIVPVALDGGITTVIAGGTGMNDGTKATTVSPGKF
CCEECCCCCEEEECCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEECCHHH
VKSALQAADGLSINAGFLAKGQGMEDPIFEQIAAGACGLKIHEDGATGNAIDLALTVADK
HHHHHHHHCCCEECCCEEECCCCCCCHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEECC
TDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILETVKYAHILPAST
CCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEECCCC
NPTIPYTVNTIAEHLDMLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SDTLAMGRIGEVATRTQMAHKMKAQFGSLKGDSEFSDNNRVKRYISKYTINPAIAHGVDS
CCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
YIGSLEVGKLADIVAEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMRDQFGTY
HHCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHEECCCCCCCCCCCCCEEEECCCCCC
GRLLTNTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSVNKKSMKNSATPNLEVDPQTF
HHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCHH
DAAVDFNDLENLEQSASELAKKLKKTSSGKYILDAEPLTEAPLAQRYFLF
EEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHCCC
>Mature Secondary Structure
MFKISRKNYSDLYGITTGDSVRLGDTNLVKVEKDLTTYGEESVFGGGKTLREGMGMNSTM
CCEECCCCCCCEEEECCCCEEEECCCCEEEEEHHHHHCCCCCCCCCCHHHHHCCCCCCEE
KLDDKLGNAEVMDLVITNALIVDYTGIYKADIGIKNGKIAAIGKSGNPHLTDNVDMIVGI
EECCCCCCHHHHHHHHHCEEEEEECCEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
STEISAGEGKIYTAGGLDTHVHLEPEIVPVALDGGITTVIAGGTGMNDGTKATTVSPGKF
CCEECCCCCEEEECCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEECCHHH
VKSALQAADGLSINAGFLAKGQGMEDPIFEQIAAGACGLKIHEDGATGNAIDLALTVADK
HHHHHHHHCCCEECCCEEECCCCCCCHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEECC
TDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILETVKYAHILPAST
CCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEECCCC
NPTIPYTVNTIAEHLDMLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SDTLAMGRIGEVATRTQMAHKMKAQFGSLKGDSEFSDNNRVKRYISKYTINPAIAHGVDS
CCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
YIGSLEVGKLADIVAEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMRDQFGTY
HHCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHEECCCCCCCCCCCCCEEEECCCCCC
GRLLTNTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSVNKKSMKNSATPNLEVDPQTF
HHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCHH
DAAVDFNDLENLEQSASELAKKLKKTSSGKYILDAEPLTEAPLAQRYFLF
EEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10555372 [H]