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The map label for this gene is udk

Identifier: 13357892

GI number: 13357892

Start: 378091

End: 378714

Strand: Reverse

Name: udk

Synonym: UU332

Alternate gene names: 13357892

Gene position: 378714-378091 (Counterclockwise)

Preceding gene: 13357912

Following gene: 13357891

Centisome position: 50.38

GC content: 28.21

Gene sequence:

>624_bases
ATGAATACTAAATCCCCAATTCTTATACTAATTGCAGGAGCTTCTGGTTCTGGAAAAACAACCTTTGCTAATGAAATTAT
TGCAAGAATTCCTAAAAATACAACAAGTGTTGTTATTTGTCAAGATTCTTACTATATTTCTAATTCACAACTAAATAAAA
AAGAACGCCGCTTAATTAATTATGATCATCCAAGTAGTTTTGAATGAGAGTTAATGCGAGAGCAATTAAGTGACATTAAA
AAACGTAAAAAAATTAAAGTACCAATCTATGATTATAAAACTGAGATTCGTTTAGATAAAACGATTGATATTAGTGATGT
TGATGTTATAGTTCTTGAAGGTATTTATGCAATTTATGATGATGTCATTAATCAAATAGCTGATTTGAAAATTTTTATTG
AAACTCCAAAAGATGAATGTTTAATTCGACGAATTCTTCGAGATGTTAATGAACGTAATCGATCATTTGAATCTGTAATT
ACTCAATGACGTAGCACTGTTAGCCCTATGTATGATCAATTTGTTGAACCAAGTAAGAAGAATGCTAATGTTAGTGTGCT
ATGAAATGAACACAATCGTGTTGCATTACATTTAATTCATAAATGAATAAATAATATACATTAA

Upstream 100 bases:

>100_bases
TAATATCTTTTTTTAAAAAAATATTTAATTAATTAAAAGGAAAAGCTACGCATAATCTATAATAATAGTAATATGTTTAA
TGATATTAAGGTTCAAAATT

Downstream 100 bases:

>100_bases
AATATCATAACTAATTTAATTTTGAATTATGTCATATTATTATAAAAGCAAATTTAGAATTACAGATCATGCATTAGCTC
GTTTTCGAGAACGTGCTGAA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLINYDHPSSFEWELMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDDVINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVI
TQWRSTVSPMYDQFVEPSKKNANVSVLWNEHNRVALHLIHKWINNIH

Sequences:

>Translated_207_residues
MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLINYDHPSSFE*ELMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDDVINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVI
TQ*RSTVSPMYDQFVEPSKKNANVSVL*NEHNRVALHLIHK*INNIH
>Mature_207_residues
MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLINYDHPSSFE*ELMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDDVINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVI
TQ*RSTVSPMYDQFVEPSKKNANVSVL*NEHNRVALHLIHK*INNIH

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=206, Percent_Identity=33.0097087378641, Blast_Score=128, Evalue=4e-30,
Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI57863312, Length=207, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI13899253, Length=204, Percent_Identity=34.8039215686275, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI209863022, Length=149, Percent_Identity=32.2147651006711, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI87082034, Length=196, Percent_Identity=39.7959183673469, Blast_Score=138, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17539892, Length=200, Percent_Identity=33.5, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539894, Length=200, Percent_Identity=33.5, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71981181, Length=210, Percent_Identity=29.0476190476191, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324339, Length=190, Percent_Identity=32.1052631578947, Blast_Score=82, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24649624, Length=212, Percent_Identity=37.2641509433962, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI221458995, Length=205, Percent_Identity=37.0731707317073, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23361; Mature: 23361

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLIN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCHHHHHEEC
YDHPSSFEELMREQLSDIKKRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDD
CCCCHHHHHHHHHHHHHHHHHCEECCCEECCCEEEEECCEECCCCCCHHHHHHHHHHHHH
VINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVITQRSTVSPMYDQFVEPSKKNA
HHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
NVSVLNEHNRVALHLIHKINNIH
CEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLIN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCHHHHHEEC
YDHPSSFEELMREQLSDIKKRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDD
CCCCHHHHHHHHHHHHHHHHHCEECCCEECCCEEEEECCEECCCCCCHHHHHHHHHHHHH
VINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVITQRSTVSPMYDQFVEPSKKNA
HHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
NVSVLNEHNRVALHLIHKINNIH
CEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA