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The map label for this gene is abf

Identifier: 15004792

GI number: 15004792

Start: 91286

End: 92530

Strand: Direct

Name: abf

Synonym: CA_P0088

Alternate gene names: 15004792

Gene position: 91286-92530 (Clockwise)

Preceding gene: 15004791

Following gene: 15004796

Centisome position: 47.54

GC content: 40.08

Gene sequence:

>1245_bases
ATGAGGAGAGTCGTTATTACAGGTTATGGTGTTATTTCGTCTTCCGGTAATGATGTGGATACTTTTTGGAGTAACATTGT
CAATGGAATATCGGGAATAAGAGAAATAACTGATCCCTCGTTTTCGAATATTGCATCTCGCATTGCCGGATATATAAATG
ATTTTAACCCCTATGAATATTTCGATAAAAGAGAAATAAGGCACTATGACTTATACACTCAATATGCATTTGCGGCAGCA
AAGCAAGCTATTGACAATGCAAATGTTAAGGAAGGTAACTTTGACACAAGTCGTGTTGGTATTTATGTTGGCTCTGGAAT
AGGAGGTATTAGCACAGTACTAAATAGCCATAAGGCTTATTTGGAGAAGGGTACACGCCATGTGTCACCATTCATGATTC
CTATGATGATTAGCAACATGGCTTCTGGTGTTATAGCAATAAAAACTGGATTTAAAGGGCCGAGTTTTTCTCCGGTGTCC
GCGTGTGCAACGGCTAATCAAGCTATCGGAGAAGCATTTTTAAGTATACGGCATGGATATACAGATGCGATTATTGCAGG
TGGCTCAGAAGCCCCTATTAATACGCTTGCGTTTTCAGGTTTCGCAAATATGAAAGCTATGTCAACTAATAATGCCAATC
CAACCGAGGCCAGCCGTCCATTCGATAAACTCCGAGATGGATTTGTTATGTCTGAAGGTGCCGGTATTCTATTCTTAGAA
GAATTAACACATGCCAAAAGACGTGGAGCAAAAATATTGGGTGAAATTATTGGATATGGTTCTACTACAGACGCTTACCA
TATTACTTCGCCAGACTACCATGGCGCGGCACGGGCTATGGAGATGGCACTGGAGATGGCGGATATTTCGGCCTCTCAGA
TTGACTATATAAACGCCCATGCCACAGGAACAAAAGGTGGAGATAAATCTGAAACCAACGCAATAAAAGCCGTATTTAAG
GAAAACGTGAAGAAACTCAAAATAAGTGCAACTAAGTCAATGACAGGACATTTATTTGGAGCTGCTGGTGGTATTGAAGC
CATTATTACACTGAAAGCTTTAGAATACGGCATTATACCTCCTACAATCAATCTGAAAAATGTTGATGAAGAATGTGACC
TTGATTATGTTCCCAACAAAGCGATTAAACATGATAGCAACTTCGCGATTTCCAACGGTTTTGGCTTTGGAGGTCACAAT
GCTTCTCTTCTCTTCAAAAAATGGAATCCAGCTATGGAATATTAA

Upstream 100 bases:

>100_bases
CAGTATCGGCGGGTACTTGGGGATTCGGCGTTTTCAAACATGATGCAGTCTATTCAGGACCAATTTTTCGAATCATTAAA
TCGTATGAGGAGGTGTTAGA

Downstream 100 bases:

>100_bases
ATCCAATAATATTTAATGGTATTCACTAACTTGTTGTTTCACTGTTATATTCTGGATATCCGTAATGTAGATAAGACGCT
TTGCTGAGTTGCAAAAATAT

Product: 3-oxoacyl-acyl-carrier protein synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRRVVITGYGVISSSGNDVDTFWSNIVNGISGIREITDPSFSNIASRIAGYINDFNPYEYFDKREIRHYDLYTQYAFAAA
KQAIDNANVKEGNFDTSRVGIYVGSGIGGISTVLNSHKAYLEKGTRHVSPFMIPMMISNMASGVIAIKTGFKGPSFSPVS
ACATANQAIGEAFLSIRHGYTDAIIAGGSEAPINTLAFSGFANMKAMSTNNANPTEASRPFDKLRDGFVMSEGAGILFLE
ELTHAKRRGAKILGEIIGYGSTTDAYHITSPDYHGAARAMEMALEMADISASQIDYINAHATGTKGGDKSETNAIKAVFK
ENVKKLKISATKSMTGHLFGAAGGIEAIITLKALEYGIIPPTINLKNVDEECDLDYVPNKAIKHDSNFAISNGFGFGGHN
ASLLFKKWNPAMEY

Sequences:

>Translated_414_residues
MRRVVITGYGVISSSGNDVDTFWSNIVNGISGIREITDPSFSNIASRIAGYINDFNPYEYFDKREIRHYDLYTQYAFAAA
KQAIDNANVKEGNFDTSRVGIYVGSGIGGISTVLNSHKAYLEKGTRHVSPFMIPMMISNMASGVIAIKTGFKGPSFSPVS
ACATANQAIGEAFLSIRHGYTDAIIAGGSEAPINTLAFSGFANMKAMSTNNANPTEASRPFDKLRDGFVMSEGAGILFLE
ELTHAKRRGAKILGEIIGYGSTTDAYHITSPDYHGAARAMEMALEMADISASQIDYINAHATGTKGGDKSETNAIKAVFK
ENVKKLKISATKSMTGHLFGAAGGIEAIITLKALEYGIIPPTINLKNVDEECDLDYVPNKAIKHDSNFAISNGFGFGGHN
ASLLFKKWNPAMEY
>Mature_414_residues
MRRVVITGYGVISSSGNDVDTFWSNIVNGISGIREITDPSFSNIASRIAGYINDFNPYEYFDKREIRHYDLYTQYAFAAA
KQAIDNANVKEGNFDTSRVGIYVGSGIGGISTVLNSHKAYLEKGTRHVSPFMIPMMISNMASGVIAIKTGFKGPSFSPVS
ACATANQAIGEAFLSIRHGYTDAIIAGGSEAPINTLAFSGFANMKAMSTNNANPTEASRPFDKLRDGFVMSEGAGILFLE
ELTHAKRRGAKILGEIIGYGSTTDAYHITSPDYHGAARAMEMALEMADISASQIDYINAHATGTKGGDKSETNAIKAVFK
ENVKKLKISATKSMTGHLFGAAGGIEAIITLKALEYGIIPPTINLKNVDEECDLDYVPNKAIKHDSNFAISNGFGFGGHN
ASLLFKKWNPAMEY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=40.1442307692308, Blast_Score=298, Evalue=8e-81,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=46.2962962962963, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI41872631, Length=425, Percent_Identity=24.9411764705882, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1787337, Length=409, Percent_Identity=44.9877750611247, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1788663, Length=410, Percent_Identity=37.3170731707317, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=34.6987951807229, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=41.1320754716981, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI212642053, Length=386, Percent_Identity=24.8704663212435, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=421, Percent_Identity=23.9904988123515, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=37.020316027088, Blast_Score=271, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24644341, Length=416, Percent_Identity=38.7019230769231, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI19920632, Length=430, Percent_Identity=26.046511627907, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI221330659, Length=430, Percent_Identity=26.046511627907, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24581345, Length=439, Percent_Identity=23.0068337129841, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44575; Mature: 44575

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVVITGYGVISSSGNDVDTFWSNIVNGISGIREITDPSFSNIASRIAGYINDFNPYEY
CCEEEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHH
FDKREIRHYDLYTQYAFAAAKQAIDNANVKEGNFDTSRVGIYVGSGIGGISTVLNSHKAY
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
LEKGTRHVSPFMIPMMISNMASGVIAIKTGFKGPSFSPVSACATANQAIGEAFLSIRHGY
HHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TDAIIAGGSEAPINTLAFSGFANMKAMSTNNANPTEASRPFDKLRDGFVMSEGAGILFLE
CCEEEECCCCCCCHHHEECCCCCCEEEECCCCCCCCCCCCHHHHHCCEEEECCCCEEEHH
ELTHAKRRGAKILGEIIGYGSTTDAYHITSPDYHGAARAMEMALEMADISASQIDYINAH
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHEEEEECC
ATGTKGGDKSETNAIKAVFKENVKKLKISATKSMTGHLFGAAGGIEAIITLKALEYGIIP
CCCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHCCCCCEEECCCCHHHEEEEEHHHCCCCC
PTINLKNVDEECDLDYVPNKAIKHDSNFAISNGFGFGGHNASLLFKKWNPAMEY
CCCCCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRRVVITGYGVISSSGNDVDTFWSNIVNGISGIREITDPSFSNIASRIAGYINDFNPYEY
CCEEEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHH
FDKREIRHYDLYTQYAFAAAKQAIDNANVKEGNFDTSRVGIYVGSGIGGISTVLNSHKAY
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
LEKGTRHVSPFMIPMMISNMASGVIAIKTGFKGPSFSPVSACATANQAIGEAFLSIRHGY
HHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TDAIIAGGSEAPINTLAFSGFANMKAMSTNNANPTEASRPFDKLRDGFVMSEGAGILFLE
CCEEEECCCCCCCHHHEECCCCCCEEEECCCCCCCCCCCCHHHHHCCEEEECCCCEEEHH
ELTHAKRRGAKILGEIIGYGSTTDAYHITSPDYHGAARAMEMALEMADISASQIDYINAH
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHEEEEECC
ATGTKGGDKSETNAIKAVFKENVKKLKISATKSMTGHLFGAAGGIEAIITLKALEYGIIP
CCCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHCCCCCEEECCCCHHHEEEEEHHHCCCCC
PTINLKNVDEECDLDYVPNKAIKHDSNFAISNGFGFGGHNASLLFKKWNPAMEY
CCCCCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]