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The map label for this gene is obgE [H]

Identifier: 15595126

GI number: 15595126

Start: 819542

End: 820528

Strand: Direct

Name: obgE [H]

Synonym: BB0781

Alternate gene names: 15595126

Gene position: 819542-820528 (Clockwise)

Preceding gene: 15595125

Following gene: 15595127

Centisome position: 89.99

GC content: 33.84

Gene sequence:

>987_bases
TTGTATAACTTTAAGGACTCTGTAAATATAACGGTAGTTTCGGGCAATGGTGGTTCTGGGTGTGTTTCTTTTTTAAGAGA
AAAGTTTAATGCAAAAGGTGGTCCAGATGGCGGAAACGGTGGGAGTGGTGGGAGTGTAATTTTCAAGGTGAGGGAAAATC
TTAGCACTTTATCTTTTTACAAAAATGGTCATGTGCTTTGTGCTGAAAATGGTAAACCTGGAATGGGTTTTAAAAGAAGT
GGTGCTAATGGTAAAGATTTAACTCTTTTTGTTCCTCCAAATACAGAAGTTTATAATGAAAATGATGGAACTCTTTTGTA
TAGGCTTAAAAATTTAAATGACGAATTTGTTGTTTTAAAAGGTGGCAGAGGGGGTCTTGGTAATTGGAATTTTAAAACTT
CAGTTAGAAGGGTTCCAAGGTTTGCTCAACCTGGAGAATCGGGTAATAGTTTGAGCGTGCGTCTTGAACTTTTTTTGGTG
GCGGATATTGGGCTTGTTGGATTACCCAATGCTGGTAAATCTTCTCTTCTTAATAGGATAACCTCAGCAAAATCTAGGGT
CGCAAATTATCCTTTTACAACAAAGATTCCTCATCTTGGTATGCTCAGGCGTTCTTATGATGATTTGATTATTGCAGATA
TTCCCGGAATAATTAAAGGTGCTAGTTTTGGAGTAGGGCTCGGGACTAAATTTTTAAAGCATATTGCTAAAACTAAAATT
TTAGCTTTGGTTATTGATATTTCTGAAGCAAATTTTTTGGAGTCATATAACATTCTTTTAAATGAATTAAAATCTTATAG
CCATAAGCTTTTTAATAAAAAAAAAATTATTATTGCCAACAAGCTTGATTTGGACGGTTCTGAGAAAAATTTTGATTGCC
TGATAAAAGCCTTAGGAAAAGAAAAGGTTGTTGGCATCTCTATTTATGAGAATAGAGGAATTGATGAACTTATTAAAGAA
TTTTTTATTTTGGCTAAAACTTTTTAA

Upstream 100 bases:

>100_bases
AGAGTTTAAAACTTTAAAGGGGCGAAAATACGTAAGTATTGTTTAGTTTTAATTGAAAAGATTGGAGATTTTTGGTTTTA
ATTGAAAAATTGGAGAAAGT

Downstream 100 bases:

>100_bases
TAAAATTGATTTTTATTGTGGGCTTTTTATTTTTAAGACTTGGTTTTTGGATATCAGATTTTATTTAGGAAAGAAATCGT
GAGAATTGCAATATTAGGGG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MYNFKDSVNITVVSGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVRENLSTLSFYKNGHVLCAENGKPGMGFKRS
GANGKDLTLFVPPNTEVYNENDGTLLYRLKNLNDEFVVLKGGRGGLGNWNFKTSVRRVPRFAQPGESGNSLSVRLELFLV
ADIGLVGLPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGMLRRSYDDLIIADIPGIIKGASFGVGLGTKFLKHIAKTKI
LALVIDISEANFLESYNILLNELKSYSHKLFNKKKIIIANKLDLDGSEKNFDCLIKALGKEKVVGISIYENRGIDELIKE
FFILAKTF

Sequences:

>Translated_328_residues
MYNFKDSVNITVVSGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVRENLSTLSFYKNGHVLCAENGKPGMGFKRS
GANGKDLTLFVPPNTEVYNENDGTLLYRLKNLNDEFVVLKGGRGGLGNWNFKTSVRRVPRFAQPGESGNSLSVRLELFLV
ADIGLVGLPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGMLRRSYDDLIIADIPGIIKGASFGVGLGTKFLKHIAKTKI
LALVIDISEANFLESYNILLNELKSYSHKLFNKKKIIIANKLDLDGSEKNFDCLIKALGKEKVVGISIYENRGIDELIKE
FFILAKTF
>Mature_328_residues
MYNFKDSVNITVVSGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVRENLSTLSFYKNGHVLCAENGKPGMGFKRS
GANGKDLTLFVPPNTEVYNENDGTLLYRLKNLNDEFVVLKGGRGGLGNWNFKTSVRRVPRFAQPGESGNSLSVRLELFLV
ADIGLVGLPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGMLRRSYDDLIIADIPGIIKGASFGVGLGTKFLKHIAKTKI
LALVIDISEANFLESYNILLNELKSYSHKLFNKKKIIIANKLDLDGSEKNFDCLIKALGKEKVVGISIYENRGIDELIKE
FFILAKTF

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=330, Percent_Identity=37.5757575757576, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI111955139, Length=251, Percent_Identity=36.6533864541833, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI111955063, Length=164, Percent_Identity=37.1951219512195, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789574, Length=305, Percent_Identity=42.2950819672131, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787454, Length=99, Percent_Identity=37.3737373737374, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=322, Percent_Identity=36.3354037267081, Blast_Score=144, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=332, Percent_Identity=31.3253012048193, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=163, Percent_Identity=39.8773006134969, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321612, Length=123, Percent_Identity=35.7723577235772, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=105, Percent_Identity=34.2857142857143, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20129375, Length=318, Percent_Identity=39.937106918239, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24585318, Length=221, Percent_Identity=35.7466063348416, Blast_Score=120, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35736; Mature: 35736

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00095 C5_MTASE_2 ; PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNFKDSVNITVVSGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVRENLSTLSFY
CCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
KNGHVLCAENGKPGMGFKRSGANGKDLTLFVPPNTEVYNENDGTLLYRLKNLNDEFVVLK
CCCCEEEECCCCCCCCEECCCCCCCEEEEEECCCCCEEECCCCEEEEEEECCCCCEEEEE
GGRGGLGNWNFKTSVRRVPRFAQPGESGNSLSVRLELFLVADIGLVGLPNAGKSSLLNRI
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHH
TSAKSRVANYPFTTKIPHLGMLRRSYDDLIIADIPGIIKGASFGVGLGTKFLKHIAKTKI
HHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHEE
LALVIDISEANFLESYNILLNELKSYSHKLFNKKKIIIANKLDLDGSEKNFDCLIKALGK
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCC
EKVVGISIYENRGIDELIKEFFILAKTF
CEEEEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYNFKDSVNITVVSGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVRENLSTLSFY
CCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
KNGHVLCAENGKPGMGFKRSGANGKDLTLFVPPNTEVYNENDGTLLYRLKNLNDEFVVLK
CCCCEEEECCCCCCCCEECCCCCCCEEEEEECCCCCEEECCCCEEEEEEECCCCCEEEEE
GGRGGLGNWNFKTSVRRVPRFAQPGESGNSLSVRLELFLVADIGLVGLPNAGKSSLLNRI
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHH
TSAKSRVANYPFTTKIPHLGMLRRSYDDLIIADIPGIIKGASFGVGLGTKFLKHIAKTKI
HHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHEE
LALVIDISEANFLESYNILLNELKSYSHKLFNKKKIIIANKLDLDGSEKNFDCLIKALGK
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCC
EKVVGISIYENRGIDELIKEFFILAKTF
CEEEEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA