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The map label for this gene is coaX

Identifier: 15594872

GI number: 15594872

Start: 537520

End: 538308

Strand: Direct

Name: coaX

Synonym: BB0527

Alternate gene names: 15594872

Gene position: 537520-538308 (Clockwise)

Preceding gene: 15594871

Following gene: 15594874

Centisome position: 59.02

GC content: 26.74

Gene sequence:

>789_bases
ATGAATAAACCTTTATTATCAGAATTGATAATTGATATTGGAAATACCAGCATTGCTTTTGCCTTATTTAAAGATAATCA
AGTTAATTTATTTATTAAAATGAAAACAAATCTTATGTTAAGGTATGATGAGGTTTATAGCTTTTTTGAAGAAAATTTTG
ATTTTAATGTAAATAAAGTTTTTATAAGCAGCGTTGTTCCTATTCTTAATGAAACATTTAAAAATGTCATTTTTTCTTTT
TTTAAGATAAAGCCTTTGTTTATTGGTTTTGATTTGAATTATGATTTGACATTTAATCCTTACAAAAGCGATAAATTTTT
GCTAGGTTCAGACGTTTTTGCCAATCTTGTTGCAGCCATTGAAAATTATTCATTTGAAAATGTTTTAGTAGTAGACCTTG
GAACTGCTTGCACCATTTTTGCTGTTAGCAGGCAAGATGGAATACTCGGTGGTATTATAAATTCTGGTCCTTTGATAAAT
TTTAATTCTTTATTAGATAATGCCTATCTTATCAAAAAATTCCCCATTAGCACTCCAAATAATCTTTTAGAGAGAACGAC
ATCTGGGAGTGTAAACAGCGGTTTATTTTATCAATATAAGTATTTAATAGAAGGTGTTTATCGTGATATTAAGCAGATGT
ATAAAAAAAAATTTAATTTAATAATTACTGGGGGTAATGCGGACCTAATTTTGTCATTAATTGAGATAGAGTTTATTTTT
AATATTCATTTAACTGTAGAAGGCGTTAGAATTTTAGGAAATTCTATTGACTTTAAGTTTGTTAATTGA

Upstream 100 bases:

>100_bases
CCTTTAAACAAAATTTTGGTTATTAAAGCAACGCCCAAGAAAAAGAGAACTTTTAATCTTTTATTGAGATTTGACAAAAT
TGCAAAAAAAATAAATATTT

Downstream 100 bases:

>100_bases
AATATTTGTTTTTAAAGTTTTAAATTTTTTTGTTAAATAAATTTGGGAAGTTTTTTGTTTGGTGATTGAAATTATCTAAA
ATTGATGTAATCTCTTCATA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNKPLLSELIIDIGNTSIAFALFKDNQVNLFIKMKTNLMLRYDEVYSFFEENFDFNVNKVFISSVVPILNETFKNVIFSF
FKIKPLFIGFDLNYDLTFNPYKSDKFLLGSDVFANLVAAIENYSFENVLVVDLGTACTIFAVSRQDGILGGIINSGPLIN
FNSLLDNAYLIKKFPISTPNNLLERTTSGSVNSGLFYQYKYLIEGVYRDIKQMYKKKFNLIITGGNADLILSLIEIEFIF
NIHLTVEGVRILGNSIDFKFVN

Sequences:

>Translated_262_residues
MNKPLLSELIIDIGNTSIAFALFKDNQVNLFIKMKTNLMLRYDEVYSFFEENFDFNVNKVFISSVVPILNETFKNVIFSF
FKIKPLFIGFDLNYDLTFNPYKSDKFLLGSDVFANLVAAIENYSFENVLVVDLGTACTIFAVSRQDGILGGIINSGPLIN
FNSLLDNAYLIKKFPISTPNNLLERTTSGSVNSGLFYQYKYLIEGVYRDIKQMYKKKFNLIITGGNADLILSLIEIEFIF
NIHLTVEGVRILGNSIDFKFVN
>Mature_262_residues
MNKPLLSELIIDIGNTSIAFALFKDNQVNLFIKMKTNLMLRYDEVYSFFEENFDFNVNKVFISSVVPILNETFKNVIFSF
FKIKPLFIGFDLNYDLTFNPYKSDKFLLGSDVFANLVAAIENYSFENVLVVDLGTACTIFAVSRQDGILGGIINSGPLIN
FNSLLDNAYLIKKFPISTPNNLLERTTSGSVNSGLFYQYKYLIEGVYRDIKQMYKKKFNLIITGGNADLILSLIEIEFIF
NIHLTVEGVRILGNSIDFKFVN

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_BORBU (O51477)

Other databases:

- EMBL:   AE000783
- PIR:   F70165
- RefSeq:   NP_212661.1
- ProteinModelPortal:   O51477
- SMR:   O51477
- EnsemblBacteria:   EBBORT00000008450
- GeneID:   1195373
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0527
- NMPDR:   fig|224326.1.peg.911
- TIGR:   BB_0527
- GeneTree:   EBGT00050000007230
- HOGENOM:   HBG354445
- OMA:   GTACTIF
- ProtClustDB:   PRK13326
- BioCyc:   BBUR224326:BB_0527-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 29823; Mature: 29823

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: ACT_SITE 111-111 BINDING 94-94 BINDING 135-135 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPLLSELIIDIGNTSIAFALFKDNQVNLFIKMKTNLMLRYDEVYSFFEENFDFNVNKV
CCCHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEECCEEEEHHHHHHHHHCCCCCCHHHH
FISSVVPILNETFKNVIFSFFKIKPLFIGFDLNYDLTFNPYKSDKFLLGSDVFANLVAAI
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCEEEEECCCCCCCEEECHHHHHHHHHHH
ENYSFENVLVVDLGTACTIFAVSRQDGILGGIINSGPLINFNSLLDNAYLIKKFPISTPN
HCCCCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCEEEHHHHHCCEEEEEECCCCCCH
NLLERTTSGSVNSGLFYQYKYLIEGVYRDIKQMYKKKFNLIITGGNADLILSLIEIEFIF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHEEEEEEEEE
NIHLTVEGVRILGNSIDFKFVN
EEEEEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MNKPLLSELIIDIGNTSIAFALFKDNQVNLFIKMKTNLMLRYDEVYSFFEENFDFNVNKV
CCCHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEECCEEEEHHHHHHHHHCCCCCCHHHH
FISSVVPILNETFKNVIFSFFKIKPLFIGFDLNYDLTFNPYKSDKFLLGSDVFANLVAAI
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCEEEEECCCCCCCEEECHHHHHHHHHHH
ENYSFENVLVVDLGTACTIFAVSRQDGILGGIINSGPLINFNSLLDNAYLIKKFPISTPN
HCCCCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCEEEHHHHHCCEEEEEECCCCCCH
NLLERTTSGSVNSGLFYQYKYLIEGVYRDIKQMYKKKFNLIITGGNADLILSLIEIEFIF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHEEEEEEEEE
NIHLTVEGVRILGNSIDFKFVN
EEEEEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685