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The map label for this gene is 15594756

Identifier: 15594756

GI number: 15594756

Start: 422471

End: 423058

Strand: Direct

Name: 15594756

Synonym: BB0411

Alternate gene names: NA

Gene position: 422471-423058 (Clockwise)

Preceding gene: 15594755

Following gene: 15594757

Centisome position: 46.39

GC content: 25.17

Gene sequence:

>588_bases
ATGGTAGAACTAGCATTAACTTTGTTAAAATCAAAAAAAATTAAAAGAAGTACCAAATTCTTTGAAGACACCAACATTAA
GGGCGCTTTTCCAAAACTTGAAGATTACTTTAAAAGCGGTTATGACAGAGGACACATAGTAAGTTCTGCAGATATGTCTT
TTTCTGAAAATGCAATGAAAGATACATATTTTTTATCAAATATGTCACCTCAAAAAAGCGAATTTAATTCTGGAATTTGG
CTAAAACTTGAAAAATTAGTAAGAGAATGGGCAATCTCAAAAGGATATATATATATTATTAGCGCTGGGATTTTAACAGA
AAATAAAGGATTTATTGGTAAAAACAAAATTTTGATACCTAAAAATTTTTATAAAATAGTACTGGCAATTAATAATAACA
ATTATTATGACATAATCTCTTTTATTATCCCAAATGAAAAAGCAAAAGACTTGGATTTGGAAAATTATGTTGTTAGCGTT
GACTTAATTGAAAAAAAAACAAAGATAGATTTTTTTGAAAAACTTGATTCAAAAATTAAAAAAAATATTAAAAAAATAAA
AAACACGCATTCTTGGAAATTTAAATGA

Upstream 100 bases:

>100_bases
ATATCTTACTACTCAAATAATAAGCAAAAAACACTATACCTTAGGATATGCTGAAAGCGCAAGACAATCTGAATGGGCTG
CTTATCCGCTTAAAAGAGAA

Downstream 100 bases:

>100_bases
AATCAATATTTGCAAAGTTAAACGCTTCTATCAATCTCTTTCTTTTTATAATTTTTATTTTGGCAACAATAGTTATACTG
ACTTTCTCCTATAAAATAAA

Product: endonuclease precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADMSFSENAMKDTYFLSNMSPQKSEFNSGIW
LKLEKLVREWAISKGYIYIISAGILTENKGFIGKNKILIPKNFYKIVLAINNNNYYDIISFIIPNEKAKDLDLENYVVSV
DLIEKKTKIDFFEKLDSKIKKNIKKIKNTHSWKFK

Sequences:

>Translated_195_residues
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADMSFSENAMKDTYFLSNMSPQKSEFNSGIW
LKLEKLVREWAISKGYIYIISAGILTENKGFIGKNKILIPKNFYKIVLAINNNNYYDIISFIIPNEKAKDLDLENYVVSV
DLIEKKTKIDFFEKLDSKIKKNIKKIKNTHSWKFK
>Mature_195_residues
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADMSFSENAMKDTYFLSNMSPQKSEFNSGIW
LKLEKLVREWAISKGYIYIISAGILTENKGFIGKNKILIPKNFYKIVLAINNNNYYDIISFIIPNEKAKDLDLENYVVSV
DLIEKKTKIDFFEKLDSKIKKNIKKIKNTHSWKFK

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family

Homologues:

Organism=Homo sapiens, GI53759134, Length=183, Percent_Identity=27.8688524590164, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI224451073, Length=177, Percent_Identity=30.5084745762712, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI224451075, Length=177, Percent_Identity=30.5084745762712, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17505967, Length=165, Percent_Identity=31.5151515151515, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322253, Length=205, Percent_Identity=33.1707317073171, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI20129899, Length=188, Percent_Identity=26.063829787234, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24581065, Length=159, Percent_Identity=27.0440251572327, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUC_BORBU (O51372)

Other databases:

- EMBL:   AE000783
- PIR:   B70151
- RefSeq:   NP_212545.1
- ProteinModelPortal:   O51372
- SMR:   O51372
- EnsemblBacteria:   EBBORT00000008439
- GeneID:   1195249
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0411
- NMPDR:   fig|224326.1.peg.795
- TIGR:   BB_0411
- GeneTree:   EBGT00050000007132
- HOGENOM:   HBG713373
- OMA:   KFQSIEV
- PhylomeDB:   O51372
- ProtClustDB:   CLSK507570
- BioCyc:   BBUR224326:BB_0411-MONOMER
- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821
- Gene3D:   G3DSA:3.40.570.10
- SMART:   SM00892
- SMART:   SM00477

Pfam domain/function: PF01223 Endonuclease_NS

EC number: 3.1.30.-

Molecular weight: Translated: 22692; Mature: 22692

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: ACT_SITE 45-45

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADMSFSENAMK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHH
DTYFLSNMSPQKSEFNSGIWLKLEKLVREWAISKGYIYIISAGILTENKGFIGKNKILIP
HHEEECCCCCCHHHCCCCCEEEHHHHHHHHCCCCCEEEEEEECEEECCCCCCCCCEEEEC
KNFYKIVLAINNNNYYDIISFIIPNEKAKDLDLENYVVSVDLIEKKTKIDFFEKLDSKIK
CCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
KNIKKIKNTHSWKFK
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADMSFSENAMK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHH
DTYFLSNMSPQKSEFNSGIWLKLEKLVREWAISKGYIYIISAGILTENKGFIGKNKILIP
HHEEECCCCCCHHHCCCCCEEEHHHHHHHHCCCCCEEEEEEECEEECCCCCCCCCEEEEC
KNFYKIVLAINNNNYYDIISFIIPNEKAKDLDLENYVVSVDLIEKKTKIDFFEKLDSKIK
CCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
KNIKKIKNTHSWKFK
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685