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The map label for this gene is metA

Identifier: 255767480

GI number: 255767480

Start: 2305378

End: 2306283

Strand: Direct

Name: metA

Synonym: BSU21910

Alternate gene names: 255767480

Gene position: 2305378-2306283 (Clockwise)

Preceding gene: 16079238

Following gene: 16079251

Centisome position: 54.69

GC content: 40.84

Gene sequence:

>906_bases
TTGCCTATTAATATACCAACACACCTGCCGGCAAAACAGGTGCTTGAAAGTGAACATATATTTGTAATGGATGAAAGCAG
AGCATTTCATCAGGATATCCGGCCGCAAAAAATTATTATATTAAATTTGATGCCGAAAAAAATCCAAACAGAGACTCAGC
TTCTCAGATTGCTTGGAAATTCGCCTTTACAGGTTCATTTCACATTTTTAATCCCAAGCACACACACGCCGAAAAATACT
GCGAGAGAACACCTTGACGAATTTTACACGACTTTTTCCAATATCCGTCACAAGAGGTTTGACGGCATGATTATCACCGG
TGCGCCGATCGAGCATTTGGCGTTTGAAGAGGTTTCATATTGGGAAGAGCTCAAGGAAATCATGGAGTGGAGCAAAACAA
ATGTCACTTCAACCTTGCATATTTGCTGGGGTGCTCAAGCAGGTTTGTATTACCATTACGGTGTGGAAAAAATTCAAATG
CCGAAAAAAATCTTCGGTGTGTTCGAACATACCGTTCTTTCAAAACACGAAAGATTGGTAAGAGGTTTTGACGAGCTATA
CTACGTGCCGCATTCCCGGCATACAGATATAAATATGGAACAGCTTCAAGCAGTGCCCGAGTTAAACATTCTTACCGCAT
CAAAGGAAGCCGGGGTTTGCTTAATTGTGTCTAAAGACGAAAAACAAGTCTTTTTGACAGGGCACCCTGAATATGATACA
AATACGCTTCTTCAAGAGTATGAAAGAGATTTGGAACGAAACCTTTCTACTGTCGAGGCCCCTAAACATTATTTTGCAAA
AGGCAGCAACGAGCCAGTGAATCGCTGGAAAGCGCATGCCACATTATTGTTTATGAATTGGCTGAATTATTACGTTTACC
AAGAAACTCCTTATGAATGGGACTAA

Upstream 100 bases:

>100_bases
TTCTGTTGTTTCCCCCTCAACACGTATAGATAGATTGAAAATTGGCGTGAAAATTCCTATAATGAAGAAAATTAAACGGG
GAAATAATGGAGGTGGCACG

Downstream 100 bases:

>100_bases
TTTTTCTTTTTTTAGTGATACGCTGAGCAAAAAATATGATAAAATACATCTGATTCAGTCTGCGTATAACAAAAATTTAA
AATACTGGAATCCAAATCAT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGNSPLQVHFTFLIPSTHTPKNT
AREHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSYWEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQM
PKKIFGVFEHTVLSKHERLVRGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDT
NTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEWD

Sequences:

>Translated_301_residues
MPINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGNSPLQVHFTFLIPSTHTPKNT
AREHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSYWEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQM
PKKIFGVFEHTVLSKHERLVRGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDT
NTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEWD
>Mature_300_residues
PINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGNSPLQVHFTFLIPSTHTPKNTA
REHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSYWEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQMP
KKIFGVFEHTVLSKHERLVRGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDTN
TLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEWD

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=48.1727574750831, Blast_Score=301, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35371; Mature: 35240

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGN
CCCCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCC
SPLQVHFTFLIPSTHTPKNTAREHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSY
CCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
WEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQMPKKIFGVFEHTVLSKHERLV
HHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
RGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDT
HHHHHHEECCCCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCH
NTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEW
HHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCC
D
C
>Mature Secondary Structure 
PINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGN
CCCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCC
SPLQVHFTFLIPSTHTPKNTAREHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSY
CCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
WEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQMPKKIFGVFEHTVLSKHERLV
HHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
RGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDT
HHHHHHEECCCCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCH
NTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEW
HHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA