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The map label for this gene is frlR

Identifier: 161511067

GI number: 161511067

Start: 3346238

End: 3347026

Strand: Direct

Name: frlR

Synonym: BSU32560

Alternate gene names: 161511067

Gene position: 3346238-3347026 (Clockwise)

Preceding gene: 16080307

Following gene: 50812290

Centisome position: 79.38

GC content: 41.95

Gene sequence:

>789_bases
TTGTATTATAACGTCATAATACATTATAATATAAATAATAGGTTAAAAGGAGGCTACCCTTTGTTAAACAACGGAAGTTC
TACACCTTTATACATTCAGCTAAAACAAATCATCACTGATGACATCAAAAAGGGCGTGTATTCCCCAACCGCCAAGCTGC
CTACCGAAAACGAGCTTTGCACCAAGTATAACGTCAGCCGCATCACCGTCAGGAAAGCCATTCTCGATTTAGTCGAAGAA
GGCTATCTGATCAGGCAGCAGGGAAAGGGAACGTTCGTTAAAAGCCCTAAATTAAAACGAGAGCTGATCGCTGTAAACGG
CTACTCGGAATTTATGGAATCAACCGGCAAAAAACCGAAGCATCATGTGCTGTCCCATGACATCATTCCAGCGTCAAAAC
CCATCGCCGAAAAGCTTCAAATCCAACCCGAGAGCCCTGTGGTTGAATTAAAACGGATTTTATATAATGATGATCAGCCT
CTCACCTTTGAAGTGACGCATTATCCGCTTGATTTGTTTCCCGGCATTGATACCTTTATTGCTGACGGCGTCTCCATGCA
TGATATTTTGAAACAGCAATACAAAGTTGTACCCACGCACAATACGAAGCTATTAAACGTTGTATATGCCCAACAGGAGG
AAAGCAAATACCTGGATTGTGATATCGGGGATGCGCTGTTTGAAATTGATAAAACGGCTTTTACATCAAACGACCAGCCA
ATCTATTGCTCATTGTTTTTGATGCACACAAACCGTGTCACTTTTACCATCAACAGCCCCTACACATAA

Upstream 100 bases:

>100_bases
TGACCCGTTATTTCGTCACTGGAAACAACTTGGTCTTTCTGTTATTTTTAGAGTAATCGATTCCCATTTTTGCTATATTT
CTAAAATAAAAAATGTAAAT

Downstream 100 bases:

>100_bases
CAGGCATAAAAAACGAGACACTGCTTATAGTATTCTCGTTTTTTCACTGCTTCCCCCGTCCTCCAAGCGATAAGGATAGC
CATAGCCGAAAGCTCCGTAC

Product: DNA-binding transcriptional regulator FrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MYYNVIIHYNINNRLKGGYPLLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEE
GYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQP
LTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQP
IYCSLFLMHTNRVTFTINSPYT

Sequences:

>Translated_262_residues
MYYNVIIHYNINNRLKGGYPLLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEE
GYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQP
LTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQP
IYCSLFLMHTNRVTFTINSPYT
>Mature_262_residues
MYYNVIIHYNINNRLKGGYPLLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEE
GYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQP
LTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQP
IYCSLFLMHTNRVTFTINSPYT

Specific function: Unknown

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=230, Percent_Identity=40.8695652173913, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786950, Length=226, Percent_Identity=30.0884955752212, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788418, Length=221, Percent_Identity=28.0542986425339, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790118, Length=195, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790540, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29917; Mature: 29917

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYNVIIHYNINNRLKGGYPLLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELC
CEEEEEEEEECCCCCCCCCCEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHH
TKYNVSRITVRKAILDLVEEGYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPK
HCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEEECCHHHHHHHHCCCCC
HHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFI
HHHHCCCCCCCCCCHHHHEEECCCCCHHHHHHHHCCCCCCEEEEEEECCEECCCCCHHHH
ADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQP
HCCCCHHHHHHHHEEECCCCCCEEEEEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCC
IYCSLFLMHTNRVTFTINSPYT
EEEEEEEEECCEEEEEECCCCC
>Mature Secondary Structure
MYYNVIIHYNINNRLKGGYPLLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELC
CEEEEEEEEECCCCCCCCCCEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHH
TKYNVSRITVRKAILDLVEEGYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPK
HCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEEECCHHHHHHHHCCCCC
HHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFI
HHHHCCCCCCCCCCHHHHEEECCCCCHHHHHHHHCCCCCCEEEEEEECCEECCCCCHHHH
ADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQP
HCCCCHHHHHHHHEEECCCCCCEEEEEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCC
IYCSLFLMHTNRVTFTINSPYT
EEEEEEEEECCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]