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The map label for this gene is yvmA

Identifier: 16080562

GI number: 16080562

Start: 3605523

End: 3606734

Strand: Direct

Name: yvmA

Synonym: BSU35090

Alternate gene names: 16080562

Gene position: 3605523-3606734 (Clockwise)

Preceding gene: 16080561

Following gene: 16080567

Centisome position: 85.53

GC content: 44.06

Gene sequence:

>1212_bases
TTGGCTCATACAAAATCAAAGGCAGTATTGATCTTATACACTGTTTGCTTCAGTGCATTTTTTGCATCTTTAAGCCAGAA
CATTTATTCACCTATTCTTCCGATCATTAAAGAATCATTCCATGTTTCCACAGCTATGGTGAACCTGTCAGTCTCAGTTT
TTATGATTGTGACAGCAATAATGCAAATTATATTAGGAGCGATCATTGATTTTAAAGGCGCTCGGATCGTCTTGATTACC
GGTATTCTGGCAACGGCAGCAGCCAGCATCGGCTGTGCGGTGACTACTGACTTTACCTTGTTTCTGATATTCAGAATGAT
ACAGGCAGCCGGTTCCGCAGCACTGCCTCTTATTGCTGCCACAACGATCGGACAGCTGTTTACAGGAAATGAACGCGGGA
GTGCAATGGGAACGTATCAAATGCTCCTGTCTGTCGCACCGGCTATTGCTCCAGTTCTAGGAGGATTCATAGGCGGAGCA
GCCGGATACGAAGGGATTTTTTGGATACTTGCGGCCATCTCTATCGTTTTGCTGGTGACAAACAGCATCACCTTTCCTAA
AGATTCTCCAACTGAATCTATGCAGCAAGCCAAAGGCAATGTGTTCGCTCATTATAAATCAATATTTACAAATCGAACAG
GGAACGTCATTTTGACTTTAAGTTTTGTTCTCTTTTTCATTTATTTTGCAGTAATTGTCTACCTCCCAATATTGCTGACA
GAGCATTACCATATAGATGTGGGTATAGCAGGACTGTTATATTTGCCGCTGGCGCTGAGCACGATTGCAGGTACGTTTCT
GTTTAAAAGAATACAGGCAAAAATCGGGCTGCACACCTTGTTTATCGGAAGCAATGTGATTGCCGCCTGCAGCATCATTT
TATTTGCTGTTACACATTCCGTTTCTCTCGTTCTCATGGCTCTGACGCTGGCACTGTTTGGCATCTCGATGGGGGTTATT
CCTCCCTTGTACTCTACAATGATTACTAATGAATTTGAGCACAACAGAGGGAGTGCAATCGGAATGTTTAACTTTATCCG
ATATACAGGCATGGCAGCAGGTCCGATGGTATCTGCCTACTTGCTCACAATGATGCCGTCTGCCATGTCCTTTAGCCTCC
TAGGCCTTGGATTTGCCGCATTGAGCTTTTGCCTTCTTCCGCCAATGTTTTCGCCGCAGAAGCGCACGAAACAAAAAAAG
CACCACATGTAA

Upstream 100 bases:

>100_bases
TATTGAAGTTTCTAGAGCAGTTGACGTCAACACTTGAAGCAGAACAAACCGATGGGACTCCAGACAAACCTGTAAAGTAA
ACAAAAAGGCGGTGTACACT

Downstream 100 bases:

>100_bases
AAAAGCTGCCTTTGCGGGCAGCTTTTTTTATTTTTTTCTAAGCGGCTCTAAAATGCCTTTTTGAATCAGCAAATGGAAGA
CCGACAGGATAACGGATGCC

Product: efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTAMVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLIT
GILATAAASIGCAVTTDFTLFLIFRMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGA
AGYEGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSFVLFFIYFAVIVYLPILLT
EHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLFIGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVI
PPLYSTMITNEFEHNRGSAIGMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQKK
HHM

Sequences:

>Translated_403_residues
MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTAMVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLIT
GILATAAASIGCAVTTDFTLFLIFRMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGA
AGYEGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSFVLFFIYFAVIVYLPILLT
EHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLFIGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVI
PPLYSTMITNEFEHNRGSAIGMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQKK
HHM
>Mature_402_residues
AHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTAMVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITG
ILATAAASIGCAVTTDFTLFLIFRMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAA
GYEGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSFVLFFIYFAVIVYLPILLTE
HYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLFIGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIP
PLYSTMITNEFEHNRGSAIGMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQKKH
HM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family

Homologues:

Organism=Escherichia coli, GI48994889, Length=331, Percent_Identity=24.4712990936556, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI2367379, Length=265, Percent_Identity=24.1509433962264, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790146, Length=297, Percent_Identity=22.8956228956229, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322071, Length=304, Percent_Identity=24.3421052631579, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322070, Length=323, Percent_Identity=21.9814241486068, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319517, Length=211, Percent_Identity=22.7488151658768, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324264, Length=170, Percent_Identity=25.2941176470588, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319657, Length=142, Percent_Identity=30.2816901408451, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVMA_BACSU (O34307)

Other databases:

- EMBL:   AF017113
- EMBL:   AL009126
- PIR:   G70043
- RefSeq:   NP_391389.1
- ProteinModelPortal:   O34307
- SMR:   O34307
- EnsemblBacteria:   EBBACT00000003345
- GeneID:   936643
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35090
- NMPDR:   fig|224308.1.peg.3515
- GenoList:   BSU35090
- GeneTree:   EBGT00070000031854
- HOGENOM:   HBG340124
- OMA:   QNIYSPI
- PhylomeDB:   O34307
- ProtClustDB:   CLSK2518278
- BioCyc:   BSUB:BSU35090-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411
- PRINTS:   PR01036

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43262; Mature: 43131

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1273d740)-; HASH(0x12a674f8)-; HASH(0x12a793e4)-; HASH(0x129bef84)-; HASH(0x12797f8c)-; HASH(0x126cb3e4)-; HASH(0x127f6190)-; HASH(0x127e7424)-; HASH(0x1296043c)-; HASH(0x11c82f10)-; HASH(0x10855c7c)-; HASH(0x11018844)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCH
>Mature Secondary Structure 
AHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTAMVNLSVSVFMIVTAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFLIFRMIQAAGSAALPLIAA
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAAGYEGIFWILAAISIVLLVT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
NSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSFVLFFIYFAVIVYLPILLT
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
EHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLFIGSNVIAACSIILFAVTHS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCHHHHHHHHHHHHHHHH
VSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAIGMFNFIRYTGMAAGPMVSAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHH
LLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQKKHHM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377