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The map label for this gene is acuC

Identifier: 16080023

GI number: 16080023

Start: 3041392

End: 3042555

Strand: Direct

Name: acuC

Synonym: BSU29710

Alternate gene names: 16080023

Gene position: 3041392-3042555 (Clockwise)

Preceding gene: 16080022

Following gene: 16080037

Centisome position: 72.15

GC content: 49.4

Gene sequence:

>1164_bases
ATGAGAGACAGTGTATTTATCTATTCTCCATCCTACCAAACCTATATGTTTCATCAGGAGCATCCCTTTAATCAGCAGCG
GGTTCTGTTAACATATGATTTGCTTAAGACGATCAATGCCTTTGATGATGGAGACATTGTCACCCCCAGACTCGCTTCAG
AAGAGGAGCTTTCCCTTGTCCACACGGACGATTACATTCAGGCCGTAAAGCTTGCGGGCGCCGGAAAGCTCCCCGCTGAA
GAAGGAGAAAGCTACGGGCTCGGCACTGAAGACACACCCGTCTTTGCCGGCATGCACGAAGCGGCATCACTCTTGGTCGG
CGGCACTTTAACGGCCGCAGACTGGGTCATGTCAGGACAAGCCCTGCATGCGGCAAACCTTGGCGGAGGGCTTCATCACG
GCTTTCGCGGGAGAGCATCAGGATTCTGCATATACAACGACAGCGCTGTGGCTATTCAATATATCCAGAAAAAATATAGC
GCCAGAGTGCTTTATATTGATACGGACGCCCACCACGGGGACGGTGTGCAATTTACATTTTACGATAATCCTGACGTATG
CACGCTGTCCATTCATGAAACAGGAAGGTATTTATTCCCTGGAACCGGTCAGATCCAAGAAAAAGGAAGCGGAAAAGGAT
ATGGCTATTCCTTTAATATTCCGCTTGACGCTTTTACAGAGGATGATTCTTTTCTTGAGGCTTACCGGACAGCAGCTTCA
GAAGTCGCCGCGTATTTCGAGCCCGATGTCATTATCAGCCAAAACGGCGCCGATGCCCATTACTACGACCCGCTGACGCA
TTTATCAGCAACAATCAATATATACGAAGAAATCCCCCGTCTTGCACACACTTTGGCTCATCAATATTGCGGAGGGAAAT
GGATTGCAGTCGGAGGCGGCGGATATGATATTTGGCGTGTCGTGCCCCGCGCCTGGGCCAGAATATGGCTTGAAATGAAG
GGAATTGACCCGGGTCACGAGATCCCGCCGGAATGGATTGTTAAATGGCAAAAACAATGCCCCGTGGCCCTTCCGTCGAG
CTGGAGCGATCCGGCTGATTTATATCCTCCGATTCCCCGCAAGCCTGAAATTACAGAAAAAAATGCCCAAACTGTCAGCA
AAGCATTATATGCGATACGTTCTGAACAGCAAAGAACAAAGTAA

Upstream 100 bases:

>100_bases
TTGTCTTCCGTGTAAAAACGATGAATCCGCTGCCGTTTTTGCAGGCATTACAAAGAAATGGACACCACGTCGTATGGCCG
TCAGAGCAAAGGGATCTGCT

Downstream 100 bases:

>100_bases
AAAACGACCTTTACGAAGAGGTCGTTTTTGATTTTTTAATCACTATTTCCACACGCCGATTTTCCTTCATGTGTTCATTT
GTCTTGTTATCCTTTACTGG

Product: protein deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDYIQAVKLAGAGKLPAE
EGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYS
ARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTEDDSFLEAYRTAAS
EVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEIPRLAHTLAHQYCGGKWIAVGGGGYDIWRVVPRAWARIWLEMK
GIDPGHEIPPEWIVKWQKQCPVALPSSWSDPADLYPPIPRKPEITEKNAQTVSKALYAIRSEQQRTK

Sequences:

>Translated_387_residues
MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDYIQAVKLAGAGKLPAE
EGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYS
ARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTEDDSFLEAYRTAAS
EVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEIPRLAHTLAHQYCGGKWIAVGGGGYDIWRVVPRAWARIWLEMK
GIDPGHEIPPEWIVKWQKQCPVALPSSWSDPADLYPPIPRKPEITEKNAQTVSKALYAIRSEQQRTK
>Mature_387_residues
MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDYIQAVKLAGAGKLPAE
EGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYS
ARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTEDDSFLEAYRTAAS
EVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEIPRLAHTLAHQYCGGKWIAVGGGGYDIWRVVPRAWARIWLEMK
GIDPGHEIPPEWIVKWQKQCPVALPSSWSDPADLYPPIPRKPEITEKNAQTVSKALYAIRSEQQRTK

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family

Homologues:

Organism=Homo sapiens, GI13128860, Length=332, Percent_Identity=33.7349397590361, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI293336691, Length=283, Percent_Identity=33.5689045936396, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI8923769, Length=329, Percent_Identity=32.5227963525836, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI13128862, Length=310, Percent_Identity=31.9354838709677, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI262073092, Length=230, Percent_Identity=35.2173913043478, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI20070354, Length=278, Percent_Identity=30.5755395683453, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI30795204, Length=315, Percent_Identity=28.2539682539683, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI30795202, Length=315, Percent_Identity=28.2539682539683, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI17158039, Length=315, Percent_Identity=28.2539682539683, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI262073088, Length=224, Percent_Identity=32.1428571428571, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI153085395, Length=320, Percent_Identity=27.5, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI148539870, Length=315, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI169234807, Length=315, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI13128864, Length=264, Percent_Identity=32.1969696969697, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI62750347, Length=338, Percent_Identity=27.810650887574, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI62750349, Length=338, Percent_Identity=27.810650887574, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226529806, Length=301, Percent_Identity=28.9036544850498, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI217272877, Length=273, Percent_Identity=28.9377289377289, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI209862883, Length=257, Percent_Identity=26.0700389105058, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508561, Length=396, Percent_Identity=31.8181818181818, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17561978, Length=331, Percent_Identity=33.2326283987915, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17534739, Length=335, Percent_Identity=33.7313432835821, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193209491, Length=282, Percent_Identity=31.2056737588652, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540332, Length=310, Percent_Identity=28.7096774193548, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=310, Percent_Identity=28.7096774193548, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540334, Length=310, Percent_Identity=28.7096774193548, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193207430, Length=280, Percent_Identity=27.5, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25154020, Length=291, Percent_Identity=24.0549828178694, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25154022, Length=291, Percent_Identity=24.0549828178694, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537347, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=311, Percent_Identity=33.4405144694534, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6323999, Length=313, Percent_Identity=30.3514376996805, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6325325, Length=214, Percent_Identity=31.3084112149533, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324307, Length=368, Percent_Identity=28.2608695652174, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24657891, Length=327, Percent_Identity=32.7217125382263, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24644244, Length=318, Percent_Identity=31.7610062893082, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24642144, Length=296, Percent_Identity=29.3918918918919, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24642146, Length=296, Percent_Identity=29.3918918918919, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24642142, Length=296, Percent_Identity=29.3918918918919, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI281360899, Length=375, Percent_Identity=27.2, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360799, Length=316, Percent_Identity=28.7974683544304, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641720, Length=316, Percent_Identity=28.7974683544304, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281360801, Length=316, Percent_Identity=28.7974683544304, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24649807, Length=308, Percent_Identity=24.025974025974, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACUC_BACSU (P39067)

Other databases:

- EMBL:   L17309
- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   S39643
- RefSeq:   NP_390849.1
- ProteinModelPortal:   P39067
- SMR:   P39067
- EnsemblBacteria:   EBBACT00000001589
- GeneID:   936834
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29710
- NMPDR:   fig|224308.1.peg.2974
- GenoList:   BSU29710
- GeneTree:   EBGT00050000002068
- HOGENOM:   HBG713516
- OMA:   QHGCDTH
- PhylomeDB:   P39067
- ProtClustDB:   CLSK2752483
- BioCyc:   BSUB:BSU29710-MONOMER
- InterPro:   IPR003085
- InterPro:   IPR000286
- Gene3D:   G3DSA:3.40.800.20
- PANTHER:   PTHR10625
- PRINTS:   PR01272
- PRINTS:   PR01270

Pfam domain/function: PF00850 Hist_deacetyl

EC number: NA

Molecular weight: Translated: 42990; Mature: 42990

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLV
CCCCEEEECCCCEEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCEECCCCCCCCCEEEE
HTDDYIQAVKLAGAGKLPAEEGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQ
ECCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHCCC
ALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYSARVLYIDTDAHHGDGVQFTF
EEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEE
YDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTEDDSFLEAYRTAAS
ECCCCEEEEEEECCCCEECCCCCCHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
EVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEIPRLAHTLAHQYCGGKWIAVGGG
HHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GYDIWRVVPRAWARIWLEMKGIDPGHEIPPEWIVKWQKQCPVALPSSWSDPADLYPPIPR
CHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCCC
KPEITEKNAQTVSKALYAIRSEQQRTK
CCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLV
CCCCEEEECCCCEEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCEECCCCCCCCCEEEE
HTDDYIQAVKLAGAGKLPAEEGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQ
ECCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHCCC
ALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYSARVLYIDTDAHHGDGVQFTF
EEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEE
YDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTEDDSFLEAYRTAAS
ECCCCEEEEEEECCCCEECCCCCCHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
EVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEIPRLAHTLAHQYCGGKWIAVGGG
HHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GYDIWRVVPRAWARIWLEMKGIDPGHEIPPEWIVKWQKQCPVALPSSWSDPADLYPPIPR
CHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCCC
KPEITEKNAQTVSKALYAIRSEQQRTK
CCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377