Click here to switch to the map view.

The map label for this gene is yqkF

Identifier: 16079419

GI number: 16079419

Start: 2459326

End: 2460246

Strand: Direct

Name: yqkF

Synonym: BSU23620

Alternate gene names: 16079419

Gene position: 2459326-2460246 (Clockwise)

Preceding gene: 16079416

Following gene: 16079421

Centisome position: 58.34

GC content: 45.28

Gene sequence:

>921_bases
ATGAGAAAGCGCAAATTGGGTACATCTGATTTAGACATTAGCGAAGTCGGACTCGGCTGTATGTCTCTTGGAACTGAAAA
AAACAAAGCATTGTCCATTCTGGATGAAGCGATCGAGCTTGGCATCAACTATTTGGACACAGCGGATTTGTATGACCGGG
GACGCAATGAAGAAATTGTCGGTGATGCGATCCAAAACAGACGCCATGATATTATTCTGGCAACAAAAGCGGGAAACCGT
TGGGATGACGGAAGCGAGGGCTGGTATTGGGACCCTTCAAAAGCTTACATAAAAGAGGCGGTAAAAAAGAGCCTTACACG
TCTGAAAACAGATTATATCGACCTTTATCAGCTCCACGGCGGCACGATAGAGGACAACATTGATGAAACGATTGAAGCGT
TTGAGGAATTAAAACAAGAAGGTGTCATCCGCTACTACGGCATTTCTTCCATCCGCCCGAATGTGATTAAAGAATATGTA
AAAAAATCAAACATCGTCAGCATTATGATGCAATTCAGCCTGTTTGACAGACGCCCTGAGGAATGGCTCCCGCTTTTAGA
GGAACATCAAATCAGCGTAGTCGCCAGAGGTCCTGTTGCCAAAGGGCTCTTAACTGAAAAACCGCTTGATCAAGCTTCAG
AAAGTATGAAACAAAACGGGTACTTGTCCTATTCATTCGAGGAACTGACAAATGCCCGTAAGGCAATGGAGGAAGTGGCT
CCCGATCTTTCCATGACAGAAAAGTCGCTGCAGTATCTGCTAGCACAGCCGGCTGTCGCTTCAGTGATTACAGGCGCCAG
TAAGATTGAGCAGTTACGGGAAAATATTCAGGCAGCAAATGCACGGCGTTTAACCGAAGAGGAAATCAAAGCGCTCCAAT
CTCATACGAAACAAGACATTTACAAAGCTCATCGCTCATAG

Upstream 100 bases:

>100_bases
CATTTCAATATGTGAAAGATTGGATCTCAAAGCCATAAAAGTTGAAACTTTAGCTCCTTTATATTACGGTCAATACAAAG
CCTAAAAAAGGAGTGTGCAC

Downstream 100 bases:

>100_bases
CAGAAAAACCAGCACCTGTACGGGTGCTGGTTTATTTATATTGATGCCAATCCATTTGGCTTTCATTTAGGAGTTCTTCA
AAGCTCTTATTTTTTTCGAT

Product: NADPH-dependent aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNR
WDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYV
KKSNIVSIMMQFSLFDRRPEEWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA
PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDIYKAHRS

Sequences:

>Translated_306_residues
MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNR
WDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYV
KKSNIVSIMMQFSLFDRRPEEWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA
PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDIYKAHRS
>Mature_306_residues
MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNR
WDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYV
KKSNIVSIMMQFSLFDRRPEEWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA
PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDIYKAHRS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family

Homologues:

Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=26.6025641025641, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=26.1980830670927, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=26.6025641025641, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27436969, Length=304, Percent_Identity=28.2894736842105, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4504825, Length=301, Percent_Identity=28.2392026578073, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI223718702, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436971, Length=305, Percent_Identity=28.5245901639344, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=32.2188449848024, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788070, Length=306, Percent_Identity=30.3921568627451, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789199, Length=321, Percent_Identity=28.9719626168224, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=29.320987654321, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787674, Length=310, Percent_Identity=24.8387096774194, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=202, Percent_Identity=30.1980198019802, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082198, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994888, Length=276, Percent_Identity=25.7246376811594, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786400, Length=202, Percent_Identity=29.2079207920792, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=306, Percent_Identity=26.1437908496732, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=26.6467065868263, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=24.5398773006135, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=302, Percent_Identity=26.4900662251656, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=25.503355704698, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646155, Length=311, Percent_Identity=28.9389067524116, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646159, Length=220, Percent_Identity=28.6363636363636, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YQKF_BACSU (P54569)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   H69966
- RefSeq:   NP_390243.1
- ProteinModelPortal:   P54569
- SMR:   P54569
- EnsemblBacteria:   EBBACT00000000105
- GeneID:   938714
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23620
- NMPDR:   fig|224308.1.peg.2367
- GenoList:   BSU23620
- GeneTree:   EBGT00070000031909
- HOGENOM:   HBG605727
- OMA:   QENIRAS
- PhylomeDB:   P54569
- ProtClustDB:   CLSK2752441
- BioCyc:   BSUB:BSU23620-MONOMER
- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210
- Gene3D:   G3DSA:3.20.20.100
- PANTHER:   PTHR11732
- PRINTS:   PR00069

Pfam domain/function: PF00248 Aldo_ket_red; SSF51430 Aldo/ket_red

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34718; Mature: 34718

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIV
CCCCCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHH
GDAIQNRRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHG
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYVKKSNIVSIMMQFSLFDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA
HHHCHHHHCCEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHC
PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YKAHRS
HHHHCC
>Mature Secondary Structure
MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIV
CCCCCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHH
GDAIQNRRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHG
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYVKKSNIVSIMMQFSLFDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA
HHHCHHHHCCEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHC
PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YKAHRS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377