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The map label for this gene is coxA2 [H]

Identifier: 15607124

GI number: 15607124

Start: 1542541

End: 1544319

Strand: Direct

Name: coxA2 [H]

Synonym: aq_2192

Alternate gene names: 15607124

Gene position: 1542541-1544319 (Clockwise)

Preceding gene: 15607123

Following gene: 15607125

Centisome position: 99.43

GC content: 47.11

Gene sequence:

>1779_bases
GTGTGGGTGATGCAGGTGAGCAATGCAATTAAGTTTATAATCCTCACAGAAATTATATTTCCCACTCTACTTCTGGTGTT
CGGTATATACCACGGTGTAATGCAGGTTTTCTATAGATCAGGAATTATAAAAGCTGAAAGCTTCCTCGGAATTGATTACT
ATCAAGGCCTAACACTCCACGGAGTTATAAACGTAATCGTTTACACAACGATATTCATCGTTGGATTTTCCAACGCAATA
GTAGCTTACTCACTCAAGAAACCCTTAAGGGAAAAAGTCCAGTGGATAGCCCTCGGAATGATGGTTATCGGAACCCTTAT
GGCAGCATGGGCTATGTTCACTGGAAGGGCAACCGTACTCTACACCTTCTACCCACCTCTAATAGCTCACTGGACCTTCT
ACTTGGGAGCTGTACTCTTAGTACTAGGTTCACTGGTACCCTTTTTCTTTGATTGGATACCGAGTGCAATCCAGTGGAAG
AGGGAAAATCCCGACCAAAAACTTCCCCTTGCAGTATTCGGAACCTTTGTGAACTTCATCCTCTGGACCATAATGATCGT
TCCCGTAGCGATTGAAATACTCTTCCAGCTCCTACCCCTTTCTCTCGGACTCGTTGACGAGATTAACCCCTTACTTGCAA
GAACTCTCTTCTGGTTCTTTGGACACCCGGTAGTTTACTTCTGGTTACTCCCCGCATACGTAGCACTCTACACGATACTT
CCCAAGATTGTTTCCGAAAAAGGAAAACTTTACTCTGACCCTGCAGCAAGACTTGCGTTCATACTCTTCCTAATATTCTC
ACTGCCTGTAGGACTCCACCACCAGTTCACCGACCCTGGAATTACTAATACGTGGAAGCTCATACACGCACTCTTTACCT
TCGGTGTTGCACTTCCCAGCATGATTACCGCGTTCACGGTTGCAACGTCTCTTGAGTACAGCGTAAAGGCTGAACACCCC
GAACTCAAGAACTCCAAGTTCTACTGGTGGACCTTCCTGCCCTTCATGAGGCTTGAAGGAAACAAGTGGATGTTCTCCTA
CTTCTTCGCAGGACTCGTACTCTTCTTCATCGGAGGAATTACTGGAATAGTTAACGCTTCTTACAACGTAAACCTCGTAG
TTCACAACACCGCTTACGTTCCCGGACACTTCCACACGACAGTTGGTGGACTCGTATTACTCGTATTCTTCGCACTATCC
CTCTACATGGTATCCAAGCTAAGGGGAAGTGAAGTAAAACTGAAGGGACTAGCGGTTCTCGCACCCTACTTCTGGATGCA
GGGAATGTTCATGTTCTCTTACGCTATGATGGTAGGAGGTGTAGTAGTAGGCTTCCCCAGAAGAACCAACGCAGGACTCA
CGTACCTGAACCCCGACTCTCCCCTCTACAGACCTGAGTGGACCGGATACGCACAGCTTGCGGCAGTTGGAGGAGTACTC
CTCGCAATAGGATTTGCCTTCTACTTCGCATCACTCATAGCTACCGCTCTCGCTCCCAAAGTCAGGGAAAGTACCCTTGA
GTTCCCCATAGCTGACGCTTACCACGACGCACCCGCACCCCTTCTCAACAATCTCAAAACTTGGACCGTAGCAGCTATAA
TTCTCGCAGTACTCTCCTACATACCGCCCCTTTACGACGCATCCGTAAGAGGAGTATTCTTCAAGTCACCCGCTTACAAC
GAAAAGTTCCCGATGCCTCTGAAACAGCTCCAAGGTGCTGAAAAGAAAGAAGAAAAGAAAGAACTCTCAAAAGCTGAAGG
GGGTATCACTCAGAAATGA

Upstream 100 bases:

>100_bases
TAAAGTTTGAAAAACCCGGAGTTTACCACGTTGTTTGCCACGAGTTCTGCGGTGTTGGTCACCATGCTATGCAAGGAAAA
ATAATCGTTGAATAAAGGAG

Downstream 100 bases:

>100_bases
AACTACTCTTTTCCTTCCTTTTCCTAATAACTTTTTTATTGGCCCAAACGGGAAGTACAGGAATTCCCCCGAATGAAGCC
AAAACACTCGGAACATACGT

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MWVMQVSNAIKFIILTEIIFPTLLLVFGIYHGVMQVFYRSGIIKAESFLGIDYYQGLTLHGVINVIVYTTIFIVGFSNAI
VAYSLKKPLREKVQWIALGMMVIGTLMAAWAMFTGRATVLYTFYPPLIAHWTFYLGAVLLVLGSLVPFFFDWIPSAIQWK
RENPDQKLPLAVFGTFVNFILWTIMIVPVAIEILFQLLPLSLGLVDEINPLLARTLFWFFGHPVVYFWLLPAYVALYTIL
PKIVSEKGKLYSDPAARLAFILFLIFSLPVGLHHQFTDPGITNTWKLIHALFTFGVALPSMITAFTVATSLEYSVKAEHP
ELKNSKFYWWTFLPFMRLEGNKWMFSYFFAGLVLFFIGGITGIVNASYNVNLVVHNTAYVPGHFHTTVGGLVLLVFFALS
LYMVSKLRGSEVKLKGLAVLAPYFWMQGMFMFSYAMMVGGVVVGFPRRTNAGLTYLNPDSPLYRPEWTGYAQLAAVGGVL
LAIGFAFYFASLIATALAPKVRESTLEFPIADAYHDAPAPLLNNLKTWTVAAIILAVLSYIPPLYDASVRGVFFKSPAYN
EKFPMPLKQLQGAEKKEEKKELSKAEGGITQK

Sequences:

>Translated_592_residues
MWVMQVSNAIKFIILTEIIFPTLLLVFGIYHGVMQVFYRSGIIKAESFLGIDYYQGLTLHGVINVIVYTTIFIVGFSNAI
VAYSLKKPLREKVQWIALGMMVIGTLMAAWAMFTGRATVLYTFYPPLIAHWTFYLGAVLLVLGSLVPFFFDWIPSAIQWK
RENPDQKLPLAVFGTFVNFILWTIMIVPVAIEILFQLLPLSLGLVDEINPLLARTLFWFFGHPVVYFWLLPAYVALYTIL
PKIVSEKGKLYSDPAARLAFILFLIFSLPVGLHHQFTDPGITNTWKLIHALFTFGVALPSMITAFTVATSLEYSVKAEHP
ELKNSKFYWWTFLPFMRLEGNKWMFSYFFAGLVLFFIGGITGIVNASYNVNLVVHNTAYVPGHFHTTVGGLVLLVFFALS
LYMVSKLRGSEVKLKGLAVLAPYFWMQGMFMFSYAMMVGGVVVGFPRRTNAGLTYLNPDSPLYRPEWTGYAQLAAVGGVL
LAIGFAFYFASLIATALAPKVRESTLEFPIADAYHDAPAPLLNNLKTWTVAAIILAVLSYIPPLYDASVRGVFFKSPAYN
EKFPMPLKQLQGAEKKEEKKELSKAEGGITQK
>Mature_592_residues
MWVMQVSNAIKFIILTEIIFPTLLLVFGIYHGVMQVFYRSGIIKAESFLGIDYYQGLTLHGVINVIVYTTIFIVGFSNAI
VAYSLKKPLREKVQWIALGMMVIGTLMAAWAMFTGRATVLYTFYPPLIAHWTFYLGAVLLVLGSLVPFFFDWIPSAIQWK
RENPDQKLPLAVFGTFVNFILWTIMIVPVAIEILFQLLPLSLGLVDEINPLLARTLFWFFGHPVVYFWLLPAYVALYTIL
PKIVSEKGKLYSDPAARLAFILFLIFSLPVGLHHQFTDPGITNTWKLIHALFTFGVALPSMITAFTVATSLEYSVKAEHP
ELKNSKFYWWTFLPFMRLEGNKWMFSYFFAGLVLFFIGGITGIVNASYNVNLVVHNTAYVPGHFHTTVGGLVLLVFFALS
LYMVSKLRGSEVKLKGLAVLAPYFWMQGMFMFSYAMMVGGVVVGFPRRTNAGLTYLNPDSPLYRPEWTGYAQLAAVGGVL
LAIGFAFYFASLIATALAPKVRESTLEFPIADAYHDAPAPLLNNLKTWTVAAIILAVLSYIPPLYDASVRGVFFKSPAYN
EKFPMPLKQLQGAEKKEEKKELSKAEGGITQK

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 66485; Mature: 66485

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]