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The map label for this gene is ycbL [C]

Identifier: 15607080

GI number: 15607080

Start: 1503518

End: 1504153

Strand: Direct

Name: ycbL [C]

Synonym: aq_2135

Alternate gene names: 15607080

Gene position: 1503518-1504153 (Clockwise)

Preceding gene: 15607079

Following gene: 15607081

Centisome position: 96.92

GC content: 48.9

Gene sequence:

>636_bases
ATGATAATTAAGGTAATACCGGTCGGTCCCATAGCCGTAAACTGCTCGGTAGTGGCGGACGAAAAGAGTGGAGAAGCCAT
AATAATTGACCCCGGAGCGGAGGCGGAAAAGATTTTAGAAGCTGTGAAGGACTTCAAAGTTGTGGGAATAGTTGCGACCC
ACGGACACATAGACCACGTGGGGCAGGTTGGGAAACTCAAAGAACTCTTTGACGTCCCTTTTTACATGAATCCACTTGAC
AAGTTTTTAATTAACGACGAGATTTGGAGCGGTTTTGCTTCCTACATCGGTGCGGTTCCCTGTCCCGAGCCCGATGTAGA
GATAAGTGAAGGAGACGTTATAAGAGTGGGAGATGTGGAATTTAAAGTCCTTCACACACCGGGACACACGCCCGGGCTTT
GCTGTCTTTACGAGGAAAAGAGGAGGGTTTTGATAGCGGGGGACCTTCTCTTTAAGGGAAGCGTGGGGAGGTGGGACCTT
CCAGGAGGAAACCTCGTGGAGCTTAAAAAATCCGTAAAAAGGGTTCTTACAGAGCTTCCGCAGGACACACTCGTTATATG
CGGGCACTACGACGAGACAACGATAGGGCAGGAAAGGGCTTTTAATCCCTTTGCAGGAGAGCTTTTGAATGGATGA

Upstream 100 bases:

>100_bases
AAGGCTATAAAGGTTTACGACACTTCCTCTCTCGGCTGTTCAACTAGCCTCGTTCCAGAAAGGTGGAGACTTTACAGAAA
GGAGATGGAAGGTGAGTTCA

Downstream 100 bases:

>100_bases
AGTAGTAAGGCTTGAACACATTTACAAGGAGATAGAAGGAAGAGTAATATTGAAAGATGTAAATTTTTCCGTTTACAAGG
GGGAGATTTTCTCCATAATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIIKVIPVGPIAVNCSVVADEKSGEAIIIDPGAEAEKILEAVKDFKVVGIVATHGHIDHVGQVGKLKELFDVPFYMNPLD
KFLINDEIWSGFASYIGAVPCPEPDVEISEGDVIRVGDVEFKVLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDL
PGGNLVELKKSVKRVLTELPQDTLVICGHYDETTIGQERAFNPFAGELLNG

Sequences:

>Translated_211_residues
MIIKVIPVGPIAVNCSVVADEKSGEAIIIDPGAEAEKILEAVKDFKVVGIVATHGHIDHVGQVGKLKELFDVPFYMNPLD
KFLINDEIWSGFASYIGAVPCPEPDVEISEGDVIRVGDVEFKVLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDL
PGGNLVELKKSVKRVLTELPQDTLVICGHYDETTIGQERAFNPFAGELLNG
>Mature_211_residues
MIIKVIPVGPIAVNCSVVADEKSGEAIIIDPGAEAEKILEAVKDFKVVGIVATHGHIDHVGQVGKLKELFDVPFYMNPLD
KFLINDEIWSGFASYIGAVPCPEPDVEISEGDVIRVGDVEFKVLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDL
PGGNLVELKKSVKRVLTELPQDTLVICGHYDETTIGQERAFNPFAGELLNG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family

Homologues:

Organism=Homo sapiens, GI41327741, Length=201, Percent_Identity=28.3582089552239, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI42822880, Length=170, Percent_Identity=28.8235294117647, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=38.6792452830189, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17538952, Length=194, Percent_Identity=28.8659793814433, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221330176, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667703, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356335, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24667711, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2135_AQUAE (O67893)

Other databases:

- EMBL:   AE000657
- PIR:   A70483
- RefSeq:   NP_214462.1
- ProteinModelPortal:   O67893
- GeneID:   1193882
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_2135
- NMPDR:   fig|224324.1.peg.1477
- HOGENOM:   HBG753931
- OMA:   CVIFDPG
- PhylomeDB:   O67893
- ProtClustDB:   CLSK2748559
- BioCyc:   AAEO224324:AQ_2135-MONOMER
- InterPro:   IPR001279
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 22959; Mature: 22959

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKVIPVGPIAVNCSVVADEKSGEAIIIDPGAEAEKILEAVKDFKVVGIVATHGHIDHV
CEEEEEECCCEEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHCCEEEEEEEECCCHHHH
GQVGKLKELFDVPFYMNPLDKFLINDEIWSGFASYIGAVPCPEPDVEISEGDVIRVGDVE
CCHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEECCCCEEEECCEE
FKVLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDLPGGNLVELKKSVKRVLTELP
EEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCC
QDTLVICGHYDETTIGQERAFNPFAGELLNG
CCEEEEEECCCCCCCCHHHCCCCHHHHHCCC
>Mature Secondary Structure
MIIKVIPVGPIAVNCSVVADEKSGEAIIIDPGAEAEKILEAVKDFKVVGIVATHGHIDHV
CEEEEEECCCEEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHCCEEEEEEEECCCHHHH
GQVGKLKELFDVPFYMNPLDKFLINDEIWSGFASYIGAVPCPEPDVEISEGDVIRVGDVE
CCHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEECCCCEEEECCEE
FKVLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDLPGGNLVELKKSVKRVLTELP
EEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCC
QDTLVICGHYDETTIGQERAFNPFAGELLNG
CCEEEEEECCCCCCCCHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320