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The map label for this gene is hpnD

Identifier: 16519643

GI number: 16519643

Start: 54317

End: 55156

Strand: Direct

Name: hpnD

Synonym: NGR_a00440

Alternate gene names: NA

Gene position: 54317-55156 (Clockwise)

Preceding gene: 16519644

Following gene: 16519642

Centisome position: 10.13

GC content: 60.12

Gene sequence:

>840_bases
ATGAGGGCGGAGGCGGCGGCCCACGCGAACCACCGCTCTACGGCCCTTGGCAGCTCGTTCTATCTGGGAATGCGTACCCT
CCCGCCGGTGCAGCGCGAGGCGATATTCCAGATCTACAGCTTCTGCCGCCAGGTCGACGACATCGCCGACTCCGACGAAC
CGCGCGAGCACCGCCTTGCTGCACTTCAGCAATGGCGCGATCACATTGACGCGCTCTACCAATGTGTACCGCCGCCGCGG
CTAAAGGACTATCTCGCCTCGGTAACGACCTTCGGGCTGAAGCGAGAGGATTTCCTAGCCGTTGTCGACGGCATGGAAAT
GGACGTACTACAAGACATCCGCGCGCCCAAAATGGCAACCCTGGATCTCTATTGCGACCGTGTCGCCAGCGCCGTGGGAA
GGATGTCGGTGCGTGTGTTCGGCTTGAGCGAGGAGGATGGCATTGCACTTGCGCATCACCTCGGTCGTGCGCTGCAACTC
ACCAACATCCTGCGCGACATAGACGAGGATGCTGGGCTGGGTCGGCTCTATATACCACGCGAAAGCCTCGATCACGCCGG
TATCACCAGCAGCGACCCACATAAAGTCATCGCCGACAAGGCGCTGCCCAAGGCGTGCGCACCGCTGGCCCAACGCGCGA
TGATGCATTTTGCCGAATCCGACGAGATCATGAATTGCAACCCGCGCAGAATAGTACGCGCCCCCACCATCATGTCCAAA
TGTTACCGCGCGATCTTGGACCTGCTGCTGATAAGGGGTTTTGCGGCTCCCCGGGAACCGGTGCGTGTAACCAATCTCAC
AAAGCGCGCCATTCTCTTCCGTTACGCCTTGATGTTGTGA

Upstream 100 bases:

>100_bases
CGCCGCTTGAGCTGCTGCTCCATGGCGTCGGCGCAATGGCAAACGAAGCCGCGCGCCGTGCGTTCGGCCGCGGTACGCGA
TTCAAGACGACTGTCGACGT

Downstream 100 bases:

>100_bases
TGCCAAAAAATGTTCACATTATCGGCGCCGGGATCTCCGGCCTTTCCGCGGCCGTGCAGTTGAGCAATGCAGGTTTGCCG
GTGCATGTCTATGAAGCGAC

Product: squalene synthase; HpnD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRAEAAAHANHRSTALGSSFYLGMRTLPPVQREAIFQIYSFCRQVDDIADSDEPREHRLAALQQWRDHIDALYQCVPPPR
LKDYLASVTTFGLKREDFLAVVDGMEMDVLQDIRAPKMATLDLYCDRVASAVGRMSVRVFGLSEEDGIALAHHLGRALQL
TNILRDIDEDAGLGRLYIPRESLDHAGITSSDPHKVIADKALPKACAPLAQRAMMHFAESDEIMNCNPRRIVRAPTIMSK
CYRAILDLLLIRGFAAPREPVRVTNLTKRAILFRYALML

Sequences:

>Translated_279_residues
MRAEAAAHANHRSTALGSSFYLGMRTLPPVQREAIFQIYSFCRQVDDIADSDEPREHRLAALQQWRDHIDALYQCVPPPR
LKDYLASVTTFGLKREDFLAVVDGMEMDVLQDIRAPKMATLDLYCDRVASAVGRMSVRVFGLSEEDGIALAHHLGRALQL
TNILRDIDEDAGLGRLYIPRESLDHAGITSSDPHKVIADKALPKACAPLAQRAMMHFAESDEIMNCNPRRIVRAPTIMSK
CYRAILDLLLIRGFAAPREPVRVTNLTKRAILFRYALML
>Mature_279_residues
MRAEAAAHANHRSTALGSSFYLGMRTLPPVQREAIFQIYSFCRQVDDIADSDEPREHRLAALQQWRDHIDALYQCVPPPR
LKDYLASVTTFGLKREDFLAVVDGMEMDVLQDIRAPKMATLDLYCDRVASAVGRMSVRVFGLSEEDGIALAHHLGRALQL
TNILRDIDEDAGLGRLYIPRESLDHAGITSSDPHKVIADKALPKACAPLAQRAMMHFAESDEIMNCNPRRIVRAPTIMSK
CYRAILDLLLIRGFAAPREPVRVTNLTKRAILFRYALML

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4AC_RHISN (P55350)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_443763.1
- ProteinModelPortal:   P55350
- GeneID:   962247
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a00440
- HOGENOM:   HBG693191
- ProtClustDB:   CLSK808988
- InterPro:   IPR002060
- InterPro:   IPR017828
- InterPro:   IPR019845
- InterPro:   IPR008949
- Gene3D:   G3DSA:1.10.600.10
- TIGRFAMs:   TIGR03465

Pfam domain/function: PF00494 SQS_PSY; SSF48576 Terpenoid_synth

EC number: =2.5.1.32

Molecular weight: Translated: 31355; Mature: 31355

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1; PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEAAAHANHRSTALGSSFYLGMRTLPPVQREAIFQIYSFCRQVDDIADSDEPREHRLA
CCCCHHHHCCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ALQQWRDHIDALYQCVPPPRLKDYLASVTTFGLKREDFLAVVDGMEMDVLQDIRAPKMAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
LDLYCDRVASAVGRMSVRVFGLSEEDGIALAHHLGRALQLTNILRDIDEDAGLGRLYIPR
HHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCH
ESLDHAGITSSDPHKVIADKALPKACAPLAQRAMMHFAESDEIMNCNPRRIVRAPTIMSK
HHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
CYRAILDLLLIRGFAAPREPVRVTNLTKRAILFRYALML
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRAEAAAHANHRSTALGSSFYLGMRTLPPVQREAIFQIYSFCRQVDDIADSDEPREHRLA
CCCCHHHHCCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ALQQWRDHIDALYQCVPPPRLKDYLASVTTFGLKREDFLAVVDGMEMDVLQDIRAPKMAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
LDLYCDRVASAVGRMSVRVFGLSEEDGIALAHHLGRALQLTNILRDIDEDAGLGRLYIPR
HHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCH
ESLDHAGITSSDPHKVIADKALPKACAPLAQRAMMHFAESDEIMNCNPRRIVRAPTIMSK
HHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
CYRAILDLLLIRGFAAPREPVRVTNLTKRAILFRYALML
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424