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The map label for this gene is purO [H]

Identifier: 15668807

GI number: 15668807

Start: 554708

End: 555337

Strand: Direct

Name: purO [H]

Synonym: MJ0626

Alternate gene names: 15668807

Gene position: 554708-555337 (Clockwise)

Preceding gene: 15668806

Following gene: 15668808

Centisome position: 33.32

GC content: 33.97

Gene sequence:

>630_bases
ATGGTAGGGAGAGGTGAATTTATGTATATTGGAAGATTCTTAGTTGTTGGAAAAACTAAAGAAGGAAAACCATTCGCTGC
CTATAGAGTCTCAAGTAGAAGCTTTCCAAACAGAGAGGCAAAGAAAATGGATGACAATACAGTTGCAATAATTCCAAAGG
ATTTGAATGAGATGTTTAAAAACCCATATATCACATACAATTGCATAAAGGTTATTGATAAAACGATTGTTGTTTCTAAC
GGAACACATACTGACTTTATAGCTGAAAAATTGCACTTTGGAAAGAGAGATGCGTTAGCTTACGTATTGGCAGTTATGGA
CTATGAAAAAGATGATTATAAGACCCCAAGGATTGCGGCTATTTTAGATGAAAACGAATGCTATATGGGTTATGTTGCTC
ATGATGACATTAGAGTTAAGAAAGTTGAACTAAAAGATGGGAAAGGCTATTATTTGGGAGTTTATAACGCCTGTAAAATA
GATGAAAACCAGATTATAGATATTAAAGGAGAGACAGCTGAAGAGATAGCAGATTATATATTAAATTATGAGGAATTTGA
GCATCCTGTTGCATGTGCTGTTGCTGTTATTGATAAAGATGGGATAAAAATAGCTACTAAGGGCAAATAA

Upstream 100 bases:

>100_bases
TGAAATAAAGTTAAGATTTTAAGGCTAAACCTAAAAGATTTTTTATTATGTAATGAAACCATTAAGGTTTTAAAATACTC
AAAACAATATAAATGCTATT

Downstream 100 bases:

>100_bases
TAATTTTTTATAATACTTTTTGGTGAAATTATGGAAATTGATGTTAAAAGCCCAGATTTAATTATCAATACTATAAGAGG
TAATGAGAAAATATATTTTG

Product: IMP cyclohydrolase

Products: NA

Alternate protein names: IMP synthase; Inosinicase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MVGRGEFMYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFKNPYITYNCIKVIDKTIVVSN
GTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAAILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKI
DENQIIDIKGETAEEIADYILNYEEFEHPVACAVAVIDKDGIKIATKGK

Sequences:

>Translated_209_residues
MVGRGEFMYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFKNPYITYNCIKVIDKTIVVSN
GTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAAILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKI
DENQIIDIKGETAEEIADYILNYEEFEHPVACAVAVIDKDGIKIATKGK
>Mature_209_residues
MVGRGEFMYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFKNPYITYNCIKVIDKTIVVSN
GTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAAILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKI
DENQIIDIKGETAEEIADYILNYEEFEHPVACAVAVIDKDGIKIATKGK

Specific function: Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP [H]

COG id: COG3363

COG function: function code F; Archaeal IMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal IMP cyclohydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010191
- InterPro:   IPR020600 [H]

Pfam domain/function: PF07826 IMP_cyclohyd [H]

EC number: =3.5.4.10 [H]

Molecular weight: Translated: 23718; Mature: 23718

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGRGEFMYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFK
CCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCHHHHCCCCEEEEEECHHHHHHC
NPYITYNCIKVIDKTIVVSNGTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAA
CCCEEEHHHHHHCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
ILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKIDENQIIDIKGETAEEIADYI
EEECCCEEEEEEECCCEEEEEEEEECCCEEEEEECEEEEECCCCEEEECCCCHHHHHHHH
LNYEEFEHPVACAVAVIDKDGIKIATKGK
HCHHHHCCCEEEEEEEEECCCEEEEECCC
>Mature Secondary Structure
MVGRGEFMYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFK
CCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCHHHHCCCCEEEEEECHHHHHHC
NPYITYNCIKVIDKTIVVSNGTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAA
CCCEEEHHHHHHCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
ILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKIDENQIIDIKGETAEEIADYI
EEECCCEEEEEEECCCEEEEEEEEECCCEEEEEECEEEEECCCCEEEECCCCHHHHHHHH
LNYEEFEHPVACAVAVIDKDGIKIATKGK
HCHHHHCCCEEEEEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11844782 [H]