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The map label for this gene is lrp [C]

Identifier: 99081007

GI number: 99081007

Start: 1255482

End: 1255913

Strand: Direct

Name: lrp [C]

Synonym: TM1040_1166

Alternate gene names: 99081007

Gene position: 1255482-1255913 (Clockwise)

Preceding gene: 99081003

Following gene: 99081016

Centisome position: 39.22

GC content: 61.34

Gene sequence:

>432_bases
ATGGACAAAACGGATGAACGCCTGATCGCGGCCCTGCGCCACGATGCCCGGGCTTCGCTCTCTGATCTGGCCATGCAGCT
GGAGCTGTCGCGCACCACCGTCCGCACGCGGATCGAGCGGCTGCAATCGCGCGGGGATATTCTGGGCTTTACCGTGGTTC
TGAAAGAGGACGTGCTGCGCGATCCGGTGCGAGGTCTGATGATGATCGGCATCGAGGGGCGCGGAGCGGCGCGGATTACC
CGTCAGCTTCAGGGCTTGCCCGAAGTGCGCGCGATCCACACCACCAATGGGCGTTGGGATCTGATTGTGGAGCTCGGCAC
AGAAACGCTGGAGACGCTGGATGAGGCGCTGGCAAAGATCCGCATGTTTGATGGGGTGGTGACCAGCGAGACAAACCTTC
TTCTGGCCACCAAGAAAGATAGTCGCGTCTAA

Upstream 100 bases:

>100_bases
CCTTGATTGAGGGTGTCTCTGATATTTCTCCGATTTGAGGTGGAATACAGAGAGCAAATTGCTCATAAGGGGAGCGGATA
CCACAAAACGGAGCCGATTC

Downstream 100 bases:

>100_bases
GCGCCTGGGGTCAGGCGTTTTTGCGCGCGTGACGCGCAGCTGCAAACCAAAGCGCAGCCAATCCGAGCGAGATCACCGCG
TTCCAGCCTGCCATGGAGAG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MDKTDERLIAALRHDARASLSDLAMQLELSRTTVRTRIERLQSRGDILGFTVVLKEDVLRDPVRGLMMIGIEGRGAARIT
RQLQGLPEVRAIHTTNGRWDLIVELGTETLETLDEALAKIRMFDGVVTSETNLLLATKKDSRV

Sequences:

>Translated_143_residues
MDKTDERLIAALRHDARASLSDLAMQLELSRTTVRTRIERLQSRGDILGFTVVLKEDVLRDPVRGLMMIGIEGRGAARIT
RQLQGLPEVRAIHTTNGRWDLIVELGTETLETLDEALAKIRMFDGVVTSETNLLLATKKDSRV
>Mature_143_residues
MDKTDERLIAALRHDARASLSDLAMQLELSRTTVRTRIERLQSRGDILGFTVVLKEDVLRDPVRGLMMIGIEGRGAARIT
RQLQGLPEVRAIHTTNGRWDLIVELGTETLETLDEALAKIRMFDGVVTSETNLLLATKKDSRV

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16023; Mature: 16023

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTDERLIAALRHDARASLSDLAMQLELSRTTVRTRIERLQSRGDILGFTVVLKEDVLR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
DPVRGLMMIGIEGRGAARITRQLQGLPEVRAIHTTNGRWDLIVELGTETLETLDEALAKI
CHHHHEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEEECHHHHHHHHHHHHHH
RMFDGVVTSETNLLLATKKDSRV
HHHCCEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MDKTDERLIAALRHDARASLSDLAMQLELSRTTVRTRIERLQSRGDILGFTVVLKEDVLR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
DPVRGLMMIGIEGRGAARITRQLQGLPEVRAIHTTNGRWDLIVELGTETLETLDEALAKI
CHHHHEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEEECHHHHHHHHHHHHHH
RMFDGVVTSETNLLLATKKDSRV
HHHCCEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA