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The map label for this gene is yfjP [H]

Identifier: 99080998

GI number: 99080998

Start: 1248737

End: 1249369

Strand: Direct

Name: yfjP [H]

Synonym: TM1040_1157

Alternate gene names: 99080998

Gene position: 1248737-1249369 (Clockwise)

Preceding gene: 99080996

Following gene: 99080999

Centisome position: 39.01

GC content: 64.93

Gene sequence:

>633_bases
ATGACGGTGGGCCGCCTGATCGAGACCCCGGCCTGCGTGGCCGAAGGGGCTGCCTGGCTGGCGGCGCAAGAGCCACGCTT
TGCCGAAGCGCTCGCGCAGACCGGGGACTTGCCGCTGCGGCGCAAGCCTGACGGGTTTGCACAGCTTCTCAGCGCCATTG
TCAGCCAGCAGGTCTCGGTGGCGTCGGCCAATGCGATCTGGGCGCGGATGCGGGCCGCCAATCTTACTGGGCCGCGCAAG
ATCCAATGGGCCAGCGACGAGGATCTGCGCGCGGCCGGACTCAGTCGCCAGAAGATCCGCTATGCCCGTGCCCTGTCGGA
GGCACGCATTGATTTCAAGGCGTTACGGCACGCTCCTACAGCGGAGGTGATCGCCGAACTGACACAGGTTTCAGGGATCG
GGGTCTGGACGGCAGAGATTTACGCGATGTTTTCCTTGGGGCGCGCTGATGTCTTTGCGCCTGGCGATCTGGCCCTGCAA
GAGAGCGCGCGGATGCTTTTTGATCTGTCCGAGCGCCCCAAAGAGCGCGCCCTGCGCGAGATGGCAGAGGCCTGGTCACC
GTGGCGCTCGGTTGCGGCGCGGCTTTTGTGGGCCTATTACCATGTGGCAAAGGACAGGGAAGGGATCCGATGA

Upstream 100 bases:

>100_bases
GGGCAGGAGCGGTCATAGTCATGGCCATTGCGTAGCCCTGAACAGGTGAAGGAACAAGCGGCGTGCAGTGCACCGATACA
ATTTTCGCGCGTGGCTCCAG

Downstream 100 bases:

>100_bases
CTCGCGTTTTGACTGCCGGCCGCAAAGAGCCGCTCTCCGGGGAAACTCGTTCTGCCGTGGTGTTTCTGCACGGCTATGGC
GCCAATGGGGCTGACCTTCT

Product: HhH-GPD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTVGRLIETPACVAEGAAWLAAQEPRFAEALAQTGDLPLRRKPDGFAQLLSAIVSQQVSVASANAIWARMRAANLTGPRK
IQWASDEDLRAAGLSRQKIRYARALSEARIDFKALRHAPTAEVIAELTQVSGIGVWTAEIYAMFSLGRADVFAPGDLALQ
ESARMLFDLSERPKERALREMAEAWSPWRSVAARLLWAYYHVAKDREGIR

Sequences:

>Translated_210_residues
MTVGRLIETPACVAEGAAWLAAQEPRFAEALAQTGDLPLRRKPDGFAQLLSAIVSQQVSVASANAIWARMRAANLTGPRK
IQWASDEDLRAAGLSRQKIRYARALSEARIDFKALRHAPTAEVIAELTQVSGIGVWTAEIYAMFSLGRADVFAPGDLALQ
ESARMLFDLSERPKERALREMAEAWSPWRSVAARLLWAYYHVAKDREGIR
>Mature_209_residues
TVGRLIETPACVAEGAAWLAAQEPRFAEALAQTGDLPLRRKPDGFAQLLSAIVSQQVSVASANAIWARMRAANLTGPRKI
QWASDEDLRAAGLSRQKIRYARALSEARIDFKALRHAPTAEVIAELTQVSGIGVWTAEIYAMFSLGRADVFAPGDLALQE
SARMLFDLSERPKERALREMAEAWSPWRSVAARLLWAYYHVAKDREGIR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23233; Mature: 23102

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGRLIETPACVAEGAAWLAAQEPRFAEALAQTGDLPLRRKPDGFAQLLSAIVSQQVSV
CCCCHHHCCCHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
ASANAIWARMRAANLTGPRKIQWASDEDLRAAGLSRQKIRYARALSEARIDFKALRHAPT
HHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
AEVIAELTQVSGIGVWTAEIYAMFSLGRADVFAPGDLALQESARMLFDLSERPKERALRE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
MAEAWSPWRSVAARLLWAYYHVAKDREGIR
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVGRLIETPACVAEGAAWLAAQEPRFAEALAQTGDLPLRRKPDGFAQLLSAIVSQQVSV
CCCHHHCCCHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
ASANAIWARMRAANLTGPRKIQWASDEDLRAAGLSRQKIRYARALSEARIDFKALRHAPT
HHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
AEVIAELTQVSGIGVWTAEIYAMFSLGRADVFAPGDLALQESARMLFDLSERPKERALRE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
MAEAWSPWRSVAARLLWAYYHVAKDREGIR
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]