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The map label for this gene is mcpA [H]

Identifier: 99080868

GI number: 99080868

Start: 1100965

End: 1103352

Strand: Direct

Name: mcpA [H]

Synonym: TM1040_1027

Alternate gene names: 99080868

Gene position: 1100965-1103352 (Clockwise)

Preceding gene: 99080867

Following gene: 99080869

Centisome position: 34.4

GC content: 58.46

Gene sequence:

>2388_bases
ATGTTGCGTTTGAGTAATCTTAAACTCGGTTTGAAATTACCCCTTTTGATTGTATTTCCAGTTGTCGTGATTGTGCTCGT
TTCAGGCGCGCTGCAGTTGTTCCAGATGAAGCAGGCGGTGGAACGCGAGCATGAAGTCTCCTTCCTCGGTGTTGTGGAGG
GGCGCAAAGACGCGCTGGAATACTGGCTTGCCGAAGTTGAGGCAGAGGTCGTCGCTCTTTCTGACAGCTACGCCGTCAGA
TTGGCGACACAGGAATTCTCGGAGGCCTGGCAGACTTTTGACGGGGAGGCGTCCTCGGCGCTGCGCAGTCTCTATATTGA
CGATAACCCCAACCCGGTCGGCCAGAAAGATGTCCTGAATACCGCCGAGGATGGCTCGGCTTGGTCACAGGTGCATGAAC
GCCATCACGCCGGTCTGCGCGCGCATCTTCGCGCTCATGGCTATTATGATGTCTTCCTCTTCGATCTGGACGGGAACCTG
ATCTATTCGGTGTTCAAGGAGGATGATTTTGGCCTGAACTTTGAAACCGGGAAATACAAGGAAAGCGGTCTAGGCCAAGT
CTACCGCAATGGGCTGACCCTCGCAGAGGGGCAGTTCTTCATGAGTTCCATGGCGCCCTATGCGCCCAGTGCCGGCGCGC
AGGCGATGTTCATGTCGACGCCCGTGTTTCTCGAGGGAGAGCGCATCGGGGTGCTGGCGGTTCAGTTCCCGCTTGATGGC
ATCATGCATATTCTGTCGCAATCCGAGCAACTTGGCGAAACCGGCGTGGTCTATCTGGTCAATGAGCAAGGGCTGTCTCT
GACCGCGTCCCCTCGTGAGGGTGGGTTTGCCGCCTTCGAGGCGTTGCCGGAGCGCGAACAGATCAAGAGCGCCCTCTCGG
GCCAGTCCGGCTATTTTGATCCCGTGGTGGGGATGCATGGGGATGAGGTCCTCGCGGCCACGACCAGCGTGACCGTTCCC
AACGGGAGCGAATGGGGGCTGGTGCTGGAAATCAACCACGATGAGGCGATGGCAGTTGTCAACACGGCGATACGCAGCGC
CGTGATCGAATTGGCCATTACCATCGCGTTGGTTGTTGGCATCTCGAGCATGGCGGTGCGCGGCCTGGTAAAACGCCTCG
AACGCCTTGCGGGCCATGTGGAGAGCCTCGCTGACGAAAACTATGAAGAGGAAATCTCGGGTTGCGATCAGCGCGACGAG
GTGGGCTTTATTTCCGAGACATTGGTTCACCTGCAGGGGCGCTTGCAGGAAGGGGCTGCGGCCAAAGAACGCGAGCGTGT
GATCCAGGAGGGCAATGAGATGGTTGTCCGCACGCTCAGCAAGGCCTTGATGAACCTCGCCAAAGGCGACTTTCGCAACC
ATATCCTCGAGTTTTTCCCGGTCGAACACAAGAAACTGCGCTACAGCATCAATGATGCGATGACGGAGTTGAGCGATGTG
ATCGAAGAGGTGCGCGAGGTGGCCAGTAGCATCTCCAAAGGTGCTGCGGAGCTGAGCGAATCTGCGGACGACATGTCTTC
GCGCACCGAAAGCCAGGCCGCCACGCTTGAAGAGACCGCCGCCGCGCTAGAAGAAGTCACGGCGAGCGTCAAATCTGCCA
ATGAACACGTCATGAATGTGGAGCACACCGTCAGCCAGGCGCGCGGCATGGCCGAGAACAGCGGTGTGATCGTGACCGAA
ACCATTGAGGCGATGAACGGGATCGAGAGCTCTTCGCAACAGATCAGCCAGATCATTAGCGTCATTGACGATATTTCGTT
CCAGACCAACCTCTTGGCCCTGAACGCAGGGGTTGAGGCCGCACGCGCAGGTGAGGCGGGACGCGGCTTTGCGGTTGTTG
CCTCCGAGGTGCGCAGCCTCGCCCAGCGGTCCTCCGAAGCGGCGTTGGAAATCAAGACCCTGATCGAAACCAGTGGCGAG
CAGGTCGGGCGCGGGGTGCAGATGGTTGGCAAGACCGGCGATGCGCTGACACAGATCGTGGATCAGGTGAAGGAAATCGC
AGGCCTCATCGAAGAGATCGCCAAATCTTCGCAAGAACAATCGACCGCGCTCATCGAAATCAACGTGGGCATGTCGCAGC
TTGATCAAGTCACTCAGGCGAACGCGGCTATGGTCGAAGAGAACACAGCGGCTTCGCATCTCTTGCGCCAGGACTCGCAG
CGTCTTGCAGAATTTGTGAGCCGGTTCCGCACGCAGAAAGACGCCAAATCCGAAGAGGCGCCCAAGGCCTTGCCGGTTCC
GGCAGAAGCTGCAAAACCCACAGCTCACGGGGAAGAGTGGCAAGACAGCGCCACCGAGGCGACCCCGGTCACCGTCGACC
TGGCTGCCGACGAGGTGGACGACGTGCCCCAACCAAAGCGCGCAAATGAAAGATGGTCGGATTTCTGA

Upstream 100 bases:

>100_bases
GAAGTTTAAAGGCATATCTGCTTATTTTTTCGCCAGGTTACAGGTTTGATGTGCCGCCTCGAATGTTGTTCCGGGGCGGA
TTGTAAACGAGGGATCGAAG

Downstream 100 bases:

>100_bases
CACTCCACGCGTGCCCTGCGCAAGAGTTCTAGGGCGCGCCTGCCCCCTCAGGCCACAAACCAAGAGCGTGCCGGTTCACG
GCCGCTCTTTTTCGTTTTTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MLRLSNLKLGLKLPLLIVFPVVVIVLVSGALQLFQMKQAVEREHEVSFLGVVEGRKDALEYWLAEVEAEVVALSDSYAVR
LATQEFSEAWQTFDGEASSALRSLYIDDNPNPVGQKDVLNTAEDGSAWSQVHERHHAGLRAHLRAHGYYDVFLFDLDGNL
IYSVFKEDDFGLNFETGKYKESGLGQVYRNGLTLAEGQFFMSSMAPYAPSAGAQAMFMSTPVFLEGERIGVLAVQFPLDG
IMHILSQSEQLGETGVVYLVNEQGLSLTASPREGGFAAFEALPEREQIKSALSGQSGYFDPVVGMHGDEVLAATTSVTVP
NGSEWGLVLEINHDEAMAVVNTAIRSAVIELAITIALVVGISSMAVRGLVKRLERLAGHVESLADENYEEEISGCDQRDE
VGFISETLVHLQGRLQEGAAAKERERVIQEGNEMVVRTLSKALMNLAKGDFRNHILEFFPVEHKKLRYSINDAMTELSDV
IEEVREVASSISKGAAELSESADDMSSRTESQAATLEETAAALEEVTASVKSANEHVMNVEHTVSQARGMAENSGVIVTE
TIEAMNGIESSSQQISQIISVIDDISFQTNLLALNAGVEAARAGEAGRGFAVVASEVRSLAQRSSEAALEIKTLIETSGE
QVGRGVQMVGKTGDALTQIVDQVKEIAGLIEEIAKSSQEQSTALIEINVGMSQLDQVTQANAAMVEENTAASHLLRQDSQ
RLAEFVSRFRTQKDAKSEEAPKALPVPAEAAKPTAHGEEWQDSATEATPVTVDLAADEVDDVPQPKRANERWSDF

Sequences:

>Translated_795_residues
MLRLSNLKLGLKLPLLIVFPVVVIVLVSGALQLFQMKQAVEREHEVSFLGVVEGRKDALEYWLAEVEAEVVALSDSYAVR
LATQEFSEAWQTFDGEASSALRSLYIDDNPNPVGQKDVLNTAEDGSAWSQVHERHHAGLRAHLRAHGYYDVFLFDLDGNL
IYSVFKEDDFGLNFETGKYKESGLGQVYRNGLTLAEGQFFMSSMAPYAPSAGAQAMFMSTPVFLEGERIGVLAVQFPLDG
IMHILSQSEQLGETGVVYLVNEQGLSLTASPREGGFAAFEALPEREQIKSALSGQSGYFDPVVGMHGDEVLAATTSVTVP
NGSEWGLVLEINHDEAMAVVNTAIRSAVIELAITIALVVGISSMAVRGLVKRLERLAGHVESLADENYEEEISGCDQRDE
VGFISETLVHLQGRLQEGAAAKERERVIQEGNEMVVRTLSKALMNLAKGDFRNHILEFFPVEHKKLRYSINDAMTELSDV
IEEVREVASSISKGAAELSESADDMSSRTESQAATLEETAAALEEVTASVKSANEHVMNVEHTVSQARGMAENSGVIVTE
TIEAMNGIESSSQQISQIISVIDDISFQTNLLALNAGVEAARAGEAGRGFAVVASEVRSLAQRSSEAALEIKTLIETSGE
QVGRGVQMVGKTGDALTQIVDQVKEIAGLIEEIAKSSQEQSTALIEINVGMSQLDQVTQANAAMVEENTAASHLLRQDSQ
RLAEFVSRFRTQKDAKSEEAPKALPVPAEAAKPTAHGEEWQDSATEATPVTVDLAADEVDDVPQPKRANERWSDF
>Mature_795_residues
MLRLSNLKLGLKLPLLIVFPVVVIVLVSGALQLFQMKQAVEREHEVSFLGVVEGRKDALEYWLAEVEAEVVALSDSYAVR
LATQEFSEAWQTFDGEASSALRSLYIDDNPNPVGQKDVLNTAEDGSAWSQVHERHHAGLRAHLRAHGYYDVFLFDLDGNL
IYSVFKEDDFGLNFETGKYKESGLGQVYRNGLTLAEGQFFMSSMAPYAPSAGAQAMFMSTPVFLEGERIGVLAVQFPLDG
IMHILSQSEQLGETGVVYLVNEQGLSLTASPREGGFAAFEALPEREQIKSALSGQSGYFDPVVGMHGDEVLAATTSVTVP
NGSEWGLVLEINHDEAMAVVNTAIRSAVIELAITIALVVGISSMAVRGLVKRLERLAGHVESLADENYEEEISGCDQRDE
VGFISETLVHLQGRLQEGAAAKERERVIQEGNEMVVRTLSKALMNLAKGDFRNHILEFFPVEHKKLRYSINDAMTELSDV
IEEVREVASSISKGAAELSESADDMSSRTESQAATLEETAAALEEVTASVKSANEHVMNVEHTVSQARGMAENSGVIVTE
TIEAMNGIESSSQQISQIISVIDDISFQTNLLALNAGVEAARAGEAGRGFAVVASEVRSLAQRSSEAALEIKTLIETSGE
QVGRGVQMVGKTGDALTQIVDQVKEIAGLIEEIAKSSQEQSTALIEINVGMSQLDQVTQANAAMVEENTAASHLLRQDSQ
RLAEFVSRFRTQKDAKSEEAPKALPVPAEAAKPTAHGEEWQDSATEATPVTVDLAADEVDDVPQPKRANERWSDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=43.0769230769231, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1787690, Length=317, Percent_Identity=40.0630914826498, Blast_Score=199, Evalue=7e-52,
Organism=Escherichia coli, GI1788195, Length=323, Percent_Identity=39.938080495356, Blast_Score=199, Evalue=8e-52,
Organism=Escherichia coli, GI1788194, Length=278, Percent_Identity=41.726618705036, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1789453, Length=262, Percent_Identity=38.5496183206107, Blast_Score=162, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 86217; Mature: 86217

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLSNLKLGLKLPLLIVFPVVVIVLVSGALQLFQMKQAVEREHEVSFLGVVEGRKDALE
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
YWLAEVEAEVVALSDSYAVRLATQEFSEAWQTFDGEASSALRSLYIDDNPNPVGQKDVLN
HHHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCCHHHCC
TAEDGSAWSQVHERHHAGLRAHLRAHGYYDVFLFDLDGNLIYSVFKEDDFGLNFETGKYK
CCCCCHHHHHHHHHHHCCHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCC
ESGLGQVYRNGLTLAEGQFFMSSMAPYAPSAGAQAMFMSTPVFLEGERIGVLAVQFPLDG
CCCHHHHHHCCCCEECCHHHHHHCCCCCCCCCCCEEEECCCEEEECCCEEEEEEECCHHH
IMHILSQSEQLGETGVVYLVNEQGLSLTASPREGGFAAFEALPEREQIKSALSGQSGYFD
HHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCCC
PVVGMHGDEVLAATTSVTVPNGSEWGLVLEINHDEAMAVVNTAIRSAVIELAITIALVVG
CCCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSMAVRGLVKRLERLAGHVESLADENYEEEISGCDQRDEVGFISETLVHLQGRLQEGAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
AKERERVIQEGNEMVVRTLSKALMNLAKGDFRNHILEFFPVEHKKLRYSINDAMTELSDV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IEEVREVASSISKGAAELSESADDMSSRTESQAATLEETAAALEEVTASVKSANEHVMNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHTVSQARGMAENSGVIVTETIEAMNGIESSSQQISQIISVIDDISFQTNLLALNAGVEA
HHHHHHHCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
ARAGEAGRGFAVVASEVRSLAQRSSEAALEIKTLIETSGEQVGRGVQMVGKTGDALTQIV
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHCCCHHHHHHHH
DQVKEIAGLIEEIAKSSQEQSTALIEINVGMSQLDQVTQANAAMVEENTAASHLLRQDSQ
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RLAEFVSRFRTQKDAKSEEAPKALPVPAEAAKPTAHGEEWQDSATEATPVTVDLAADEVD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCHHC
DVPQPKRANERWSDF
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRLSNLKLGLKLPLLIVFPVVVIVLVSGALQLFQMKQAVEREHEVSFLGVVEGRKDALE
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
YWLAEVEAEVVALSDSYAVRLATQEFSEAWQTFDGEASSALRSLYIDDNPNPVGQKDVLN
HHHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCCHHHCC
TAEDGSAWSQVHERHHAGLRAHLRAHGYYDVFLFDLDGNLIYSVFKEDDFGLNFETGKYK
CCCCCHHHHHHHHHHHCCHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCC
ESGLGQVYRNGLTLAEGQFFMSSMAPYAPSAGAQAMFMSTPVFLEGERIGVLAVQFPLDG
CCCHHHHHHCCCCEECCHHHHHHCCCCCCCCCCCEEEECCCEEEECCCEEEEEEECCHHH
IMHILSQSEQLGETGVVYLVNEQGLSLTASPREGGFAAFEALPEREQIKSALSGQSGYFD
HHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCCC
PVVGMHGDEVLAATTSVTVPNGSEWGLVLEINHDEAMAVVNTAIRSAVIELAITIALVVG
CCCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSMAVRGLVKRLERLAGHVESLADENYEEEISGCDQRDEVGFISETLVHLQGRLQEGAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
AKERERVIQEGNEMVVRTLSKALMNLAKGDFRNHILEFFPVEHKKLRYSINDAMTELSDV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IEEVREVASSISKGAAELSESADDMSSRTESQAATLEETAAALEEVTASVKSANEHVMNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHTVSQARGMAENSGVIVTETIEAMNGIESSSQQISQIISVIDDISFQTNLLALNAGVEA
HHHHHHHCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
ARAGEAGRGFAVVASEVRSLAQRSSEAALEIKTLIETSGEQVGRGVQMVGKTGDALTQIV
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHCCCHHHHHHHH
DQVKEIAGLIEEIAKSSQEQSTALIEINVGMSQLDQVTQANAAMVEENTAASHLLRQDSQ
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RLAEFVSRFRTQKDAKSEEAPKALPVPAEAAKPTAHGEEWQDSATEATPVTVDLAADEVD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCHHC
DVPQPKRANERWSDF
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]