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The map label for this gene is mcpA [H]

Identifier: 99080825

GI number: 99080825

Start: 1052015

End: 1053841

Strand: Direct

Name: mcpA [H]

Synonym: TM1040_0984

Alternate gene names: 99080825

Gene position: 1052015-1053841 (Clockwise)

Preceding gene: 99080824

Following gene: 99080830

Centisome position: 32.87

GC content: 59.66

Gene sequence:

>1827_bases
ATGTTCTTAGCATCTTGGTTCCGGAACATGCCCGTGAAGCGTAAGATCCTGCTTCCTGGGATGGCTGGATTGCTCATGAT
GATCTGCGTGATCACGACTTACTGGACTCAGCGCCTGTCGACGGCGCTCTATAGCGGCTTTGAAGAGCAGGTCGCGCTGA
CTGAGTCCTACATCGCGGCGCCCCTCGCGACGGCCGCATGGAACTATGATGGCGACTTGGCCAATACGACACTGGCTTCG
CTTGCCGAGCGCGAGTCCTTTGTGTTTGCGCGTGTGGTCAGCAGCGGCGATGTGCTTGCCGAAGCCTTCAAGGGAGAGGC
GATGGAAGAGGCGTGGATCGCGCAATCTACCAGTCTGCTTGAATCCGATCAGGTGCGGCTGGAGGATGGCGATTTCACCT
ACTTCAAGACGCCCTTGATGTTCGAAGGTGAAGAAGCCGGCAATATGGTCTGGGCGCTCGACACCTCGATCATTGCCAAC
CAGATCATGAATGCCAACATTATCGCGGCCAGCCTTGGTTTTGCGATTTTCGCAGGCTTTTCGGTCGTCTTCTACCTCAT
CGCAGTTGCGGTATCGCGCCCGATCGAGAATGTGGTGACGCATATTGACGCGCTGCAGCACGGTGACACGACGCGTGAAA
TCCCCGAGGCGAACCGCCGTGATGAAATTGGCGCATTGGGCAAGGCGCTGGTCGATTTCCGCGACACATCCGCCGAGCAG
AAGCGCATGGAAGAAGAAAAACGCAAGCAGGACGCGGTGCAGGAACATGTCGTGACCGTTCTCTCCGAGGCGCTTGGCAA
GCTGTCCACCGGCGACCTCACGGTGAGCATCAAGGACGATTTCCCGGCGGATTACGAGAAGCTCAGCAAGGATTTCAACG
CTCTGGTCAATCGCCTGTTCGATACGGTTTCGGCTGTGGTCGATGCGGCGGACAGCATCCAGAACGGTTCCACCGAGATC
AGCTCGGCCTCTGACGATCTTGCGCGCCGCACCGAGAGCCAGGCGGCCACCCTTGAAGAAACCGCTGCTGCACTGGATGA
GCTGACTGCATCGGTGCGTCAGGCCGCCGAAGGGGCTGGAAGCGTGTCCAACACCATGGAAGAGGCAAAAGCCGAAGCCG
TGAACAGCGGCACCATCGTCAACAATGCCGTTTCGGCCATGACCGAGATCGAGCAATCCTCGAATCACATCTCTCAGATC
ATCGGCGTGATTGATGACATTGCCTTCCAGACCAACCTTCTGGCGCTGAACGCGGGTGTCGAAGCCGCGCGTGCAGGTGA
AGCAGGGCGCGGGTTTGCCGTGGTGGCCTCCGAGGTGCGCGCCTTGGCGCAACGCTCCTCCGATGCAGCCATGGAGATCA
AGACCCTCATCGGCGACAGCTCCAAACAGGTGGAACGTGGTGTGGATCTCGTCGGCAAGGCAGGCGATGCGCTTCACAAC
ATCGTTGAGCGTGTCACCCAGATCTCCGGCCTGATCTCTGACATTGCACAAGGCGCGAGCGAGCAATCCGCAGGTCTTGG
CGATATCAACAGCGGCATGGTGGAACTGGATCAGGTGACCCAGCAGAACGCCGCCATGGTGGAAGAGGCGACTGCCGCGA
GCCATATGCTCAAGGCCAATGCGGTCAACCTCGCGCAGATGGTTGCTCATTTCCAGCTCGGCGCCGGTGGGCGCGCGGCT
TCTGCTGCTCCAGCCCCTGCTGCAAAGGATGCCGAGACGATCGCGCCGTCGGCCCATGGCGAGGATTGGGACTATACGCC
CGAACCAAGTCAGGTGGCCGTCGCCAGCAGCGGCAACGCGGCGGCGAAGATCTGGGAAGACTTCTGA

Upstream 100 bases:

>100_bases
GTAAGATTTATGCTGCTTTTGTGGCAGAAACCTTATCGGCGCTTAAGAGAATAACAATGGATTTCGGCCAGAGTGTTCCC
AACTAATTTGGAGAAACACC

Downstream 100 bases:

>100_bases
CGCAATTGTTGCTGGTGGCCAATACGCGCCGGCCTCGATTGCAAAGCTCAGCTTACCCCGGCGCCACCTGGCGCCGGGTT
TTTCGATCTGAGCCCAATAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MFLASWFRNMPVKRKILLPGMAGLLMMICVITTYWTQRLSTALYSGFEEQVALTESYIAAPLATAAWNYDGDLANTTLAS
LAERESFVFARVVSSGDVLAEAFKGEAMEEAWIAQSTSLLESDQVRLEDGDFTYFKTPLMFEGEEAGNMVWALDTSIIAN
QIMNANIIAASLGFAIFAGFSVVFYLIAVAVSRPIENVVTHIDALQHGDTTREIPEANRRDEIGALGKALVDFRDTSAEQ
KRMEEEKRKQDAVQEHVVTVLSEALGKLSTGDLTVSIKDDFPADYEKLSKDFNALVNRLFDTVSAVVDAADSIQNGSTEI
SSASDDLARRTESQAATLEETAAALDELTASVRQAAEGAGSVSNTMEEAKAEAVNSGTIVNNAVSAMTEIEQSSNHISQI
IGVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGDSSKQVERGVDLVGKAGDALHN
IVERVTQISGLISDIAQGASEQSAGLGDINSGMVELDQVTQQNAAMVEEATAASHMLKANAVNLAQMVAHFQLGAGGRAA
SAAPAPAAKDAETIAPSAHGEDWDYTPEPSQVAVASSGNAAAKIWEDF

Sequences:

>Translated_608_residues
MFLASWFRNMPVKRKILLPGMAGLLMMICVITTYWTQRLSTALYSGFEEQVALTESYIAAPLATAAWNYDGDLANTTLAS
LAERESFVFARVVSSGDVLAEAFKGEAMEEAWIAQSTSLLESDQVRLEDGDFTYFKTPLMFEGEEAGNMVWALDTSIIAN
QIMNANIIAASLGFAIFAGFSVVFYLIAVAVSRPIENVVTHIDALQHGDTTREIPEANRRDEIGALGKALVDFRDTSAEQ
KRMEEEKRKQDAVQEHVVTVLSEALGKLSTGDLTVSIKDDFPADYEKLSKDFNALVNRLFDTVSAVVDAADSIQNGSTEI
SSASDDLARRTESQAATLEETAAALDELTASVRQAAEGAGSVSNTMEEAKAEAVNSGTIVNNAVSAMTEIEQSSNHISQI
IGVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGDSSKQVERGVDLVGKAGDALHN
IVERVTQISGLISDIAQGASEQSAGLGDINSGMVELDQVTQQNAAMVEEATAASHMLKANAVNLAQMVAHFQLGAGGRAA
SAAPAPAAKDAETIAPSAHGEDWDYTPEPSQVAVASSGNAAAKIWEDF
>Mature_608_residues
MFLASWFRNMPVKRKILLPGMAGLLMMICVITTYWTQRLSTALYSGFEEQVALTESYIAAPLATAAWNYDGDLANTTLAS
LAERESFVFARVVSSGDVLAEAFKGEAMEEAWIAQSTSLLESDQVRLEDGDFTYFKTPLMFEGEEAGNMVWALDTSIIAN
QIMNANIIAASLGFAIFAGFSVVFYLIAVAVSRPIENVVTHIDALQHGDTTREIPEANRRDEIGALGKALVDFRDTSAEQ
KRMEEEKRKQDAVQEHVVTVLSEALGKLSTGDLTVSIKDDFPADYEKLSKDFNALVNRLFDTVSAVVDAADSIQNGSTEI
SSASDDLARRTESQAATLEETAAALDELTASVRQAAEGAGSVSNTMEEAKAEAVNSGTIVNNAVSAMTEIEQSSNHISQI
IGVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGDSSKQVERGVDLVGKAGDALHN
IVERVTQISGLISDIAQGASEQSAGLGDINSGMVELDQVTQQNAAMVEEATAASHMLKANAVNLAQMVAHFQLGAGGRAA
SAAPAPAAKDAETIAPSAHGEDWDYTPEPSQVAVASSGNAAAKIWEDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=290, Percent_Identity=45.1724137931035, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367378, Length=348, Percent_Identity=42.816091954023, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788195, Length=291, Percent_Identity=45.0171821305842, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=46.6666666666667, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=39.4308943089431, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64576; Mature: 64576

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLASWFRNMPVKRKILLPGMAGLLMMICVITTYWTQRLSTALYSGFEEQVALTESYIAA
CCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PLATAAWNYDGDLANTTLASLAERESFVFARVVSSGDVLAEAFKGEAMEEAWIAQSTSLL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
ESDQVRLEDGDFTYFKTPLMFEGEEAGNMVWALDTSIIANQIMNANIIAASLGFAIFAGF
CCCCEEEECCCEEEEECCEEECCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVVFYLIAVAVSRPIENVVTHIDALQHGDTTREIPEANRRDEIGALGKALVDFRDTSAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
KRMEEEKRKQDAVQEHVVTVLSEALGKLSTGDLTVSIKDDFPADYEKLSKDFNALVNRLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
DTVSAVVDAADSIQNGSTEISSASDDLARRTESQAATLEETAAALDELTASVRQAAEGAG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSNTMEEAKAEAVNSGTIVNNAVSAMTEIEQSSNHISQIIGVIDDIAFQTNLLALNAGV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
EAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGDSSKQVERGVDLVGKAGDALHN
HHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVERVTQISGLISDIAQGASEQSAGLGDINSGMVELDQVTQQNAAMVEEATAASHMLKAN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNLAQMVAHFQLGAGGRAASAAPAPAAKDAETIAPSAHGEDWDYTPEPSQVAVASSGNA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCC
AAKIWEDF
HHHHHCCC
>Mature Secondary Structure
MFLASWFRNMPVKRKILLPGMAGLLMMICVITTYWTQRLSTALYSGFEEQVALTESYIAA
CCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PLATAAWNYDGDLANTTLASLAERESFVFARVVSSGDVLAEAFKGEAMEEAWIAQSTSLL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
ESDQVRLEDGDFTYFKTPLMFEGEEAGNMVWALDTSIIANQIMNANIIAASLGFAIFAGF
CCCCEEEECCCEEEEECCEEECCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVVFYLIAVAVSRPIENVVTHIDALQHGDTTREIPEANRRDEIGALGKALVDFRDTSAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
KRMEEEKRKQDAVQEHVVTVLSEALGKLSTGDLTVSIKDDFPADYEKLSKDFNALVNRLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
DTVSAVVDAADSIQNGSTEISSASDDLARRTESQAATLEETAAALDELTASVRQAAEGAG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSNTMEEAKAEAVNSGTIVNNAVSAMTEIEQSSNHISQIIGVIDDIAFQTNLLALNAGV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
EAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGDSSKQVERGVDLVGKAGDALHN
HHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVERVTQISGLISDIAQGASEQSAGLGDINSGMVELDQVTQQNAAMVEEATAASHMLKAN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNLAQMVAHFQLGAGGRAASAAPAPAAKDAETIAPSAHGEDWDYTPEPSQVAVASSGNA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCC
AAKIWEDF
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]