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The map label for this gene is erpA2 [H]

Identifier: 99080742

GI number: 99080742

Start: 961909

End: 962232

Strand: Reverse

Name: erpA2 [H]

Synonym: TM1040_0901

Alternate gene names: 99080742

Gene position: 962232-961909 (Counterclockwise)

Preceding gene: 99080750

Following gene: 99080739

Centisome position: 30.06

GC content: 59.26

Gene sequence:

>324_bases
ATGCAACTGCCCCCAAAAGTGACGGATCGCGCCTTTGACCGGCTCGCCGAAATCGGCGCTGCAGATCAAGGCCAGGCCCT
GCGCATCGCGGTCGAAGGCGGCGGTTGCTCGGGCTTTCAATATGAGATTGCGCTCGACACGCCCAAATCCGACGACCTGG
TGCTTGAGGGCAAAGGCCAGAAAGTCGTGGTCGATGAAATCTCGCTGCCGTTTCTCGAGAATGCCGTGATCGACTTCACC
GAAGAGCTGATCGGCGCGCGCTTTACGATCGAAAACCCCAATGCCACCTCCAGCTGTGGCTGCGGCACCTCGTTTTCCAT
GTGA

Upstream 100 bases:

>100_bases
GCGCGTACATGTGTTTCTTTTCTCCGGCAAATCTTGTCGCCTCGCGCGCACCTTTCTATATTTGCACTGACGCTGCAACA
CGCCATCGGAGAAAACCAAC

Downstream 100 bases:

>100_bases
CCCCCGTTCGGCGTGCGTTCATCCCGAACCCGTTCGCGGGTGCTTGATGTGATCGCTCAGCCTGAATCTTGAGTCTGATG
TCTCCCAGGGCGCGTTCCCT

Product: HesB/YadR/YfhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MQLPPKVTDRAFDRLAEIGAADQGQALRIAVEGGGCSGFQYEIALDTPKSDDLVLEGKGQKVVVDEISLPFLENAVIDFT
EELIGARFTIENPNATSSCGCGTSFSM

Sequences:

>Translated_107_residues
MQLPPKVTDRAFDRLAEIGAADQGQALRIAVEGGGCSGFQYEIALDTPKSDDLVLEGKGQKVVVDEISLPFLENAVIDFT
EELIGARFTIENPNATSSCGCGTSFSM
>Mature_107_residues
MQLPPKVTDRAFDRLAEIGAADQGQALRIAVEGGGCSGFQYEIALDTPKSDDLVLEGKGQKVVVDEISLPFLENAVIDFT
EELIGARFTIENPNATSSCGCGTSFSM

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=104, Percent_Identity=48.0769230769231, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786351, Length=108, Percent_Identity=42.5925925925926, Blast_Score=90, Evalue=3e-20,
Organism=Escherichia coli, GI1788877, Length=86, Percent_Identity=44.1860465116279, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1787974, Length=83, Percent_Identity=36.144578313253, Blast_Score=65, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=47.6190476190476, Blast_Score=95, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325324, Length=124, Percent_Identity=36.2903225806452, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323001, Length=100, Percent_Identity=30, Blast_Score=63, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649697, Length=108, Percent_Identity=42.5925925925926, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11384; Mature: 11384

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPPKVTDRAFDRLAEIGAADQGQALRIAVEGGGCSGFQYEIALDTPKSDDLVLEGKGQ
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEEECCCC
KVVVDEISLPFLENAVIDFTEELIGARFTIENPNATSSCGCGTSFSM
EEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLPPKVTDRAFDRLAEIGAADQGQALRIAVEGGGCSGFQYEIALDTPKSDDLVLEGKGQ
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEEECCCC
KVVVDEISLPFLENAVIDFTEELIGARFTIENPNATSSCGCGTSFSM
EEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA