BacMap

Definition	Deinococcus geothermalis DSM 11300, complete genome.
Accession	NC_008025
Length	2,467,205

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The map label for this gene is crt [H]

Identifier: 94985695

GI number: 94985695

Start: 1695041

End: 1695838

Strand: Reverse

Name: crt [H]

Synonym: Dgeo_1595

Alternate gene names: 94985695

Gene position: 1695838-1695041 (Counterclockwise)

Preceding gene: 94985696

Following gene: 94985694

Centisome position: 68.74

GC content: 66.92

Gene sequence:

>798_bases
ATGACGATGCTCGACGAACTCGAATTTCGCAACCTGCACCTTGACCAGCATGGCCCGCTCGCGGTGCTGACCGTCAGCCG
TCCCAAGGCGCTCAATGCACTCAATGCCGATACCCTCAGCGAGATCGCGCAGGCAGTGGATCTGGTGGTCGAGAATCCTG
AGATCGGCGCGCTGATCATCACCGGGGGCGGCGACCGGGCCTTTGTGGCAGGGGCCGATATCAGCGAACTGGCCACGTTG
GGCGACGTGTACGCCGGTCGCGAGCTGGCACTGGCCGGACAGGACGTGATGCACCAGATCAGCAGCCTGCCCATTCCGGT
GATTGCCGCGGTGAATGGCTTCGCGCTGGGGGGCGGCCTGGAACTCGCCCTCGCCTGTGACGTGCGGGTGGCCGCGCCGA
ATGCCAAACTCGGCCTGCCGGAAGTGACCCTGGGTCTGATTCCGGGCTTCGGCGGTACCCAGCGTCTGGCGCGGCTGATC
GGTGCGGGCCGCGCGCTCGACCTGATGCTCACGGCGCGGCAGGTGAGCGCGGAGGAGGCCCTCGCCCTGGGCTTGGTGAA
CTACGTCGCGGATGATCCGCTGATGAAGGCGCGCGAGGTGGCCGAGCAGATGCTGAAAAACGCCCCGATTGCGCTCTCGC
TGGTGAAGGAGGCGGTGCGCCGCGGCTTGGACACCACGCTGGAGGCGGGTCTGGAGGTGGAGGCCGATCTCTTCGGGATG
GCGGTGGCCACTCAGGATTTCCGTGAGGGCACCTCGGCGTTCCTCGCCAAGCGGCGCCCGGCGTTCAAGGGTGAATGA

Upstream 100 bases:

>100_bases
AGTGGCGCTGGGTGCCATCGTGACGCTGGCCGGGGGCTGAGAGACGCGGCCCGCAGCCAGGACCTCTTTTCCAGCTGCTT
TTCCGTGTCAGGATTGAACC

Downstream 100 bases:

>100_bases
GGGGGGGGACGCGATGCAAGAAGCCGAGCAAAGCGGCGTGACGGAGGAACCCAAGTTCACGCTGAGTGTCTCGGACGGCA
ATGTGCGCGAGGTGGAGGGA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTMLDELEFRNLHLDQHGPLAVLTVSRPKALNALNADTLSEIAQAVDLVVENPEIGALIITGGGDRAFVAGADISELATL
GDVYAGRELALAGQDVMHQISSLPIPVIAAVNGFALGGGLELALACDVRVAAPNAKLGLPEVTLGLIPGFGGTQRLARLI
GAGRALDLMLTARQVSAEEALALGLVNYVADDPLMKAREVAEQMLKNAPIALSLVKEAVRRGLDTTLEAGLEVEADLFGM
AVATQDFREGTSAFLAKRRPAFKGE

Sequences:

>Translated_265_residues
MTMLDELEFRNLHLDQHGPLAVLTVSRPKALNALNADTLSEIAQAVDLVVENPEIGALIITGGGDRAFVAGADISELATL
GDVYAGRELALAGQDVMHQISSLPIPVIAAVNGFALGGGLELALACDVRVAAPNAKLGLPEVTLGLIPGFGGTQRLARLI
GAGRALDLMLTARQVSAEEALALGLVNYVADDPLMKAREVAEQMLKNAPIALSLVKEAVRRGLDTTLEAGLEVEADLFGM
AVATQDFREGTSAFLAKRRPAFKGE
>Mature_264_residues
TMLDELEFRNLHLDQHGPLAVLTVSRPKALNALNADTLSEIAQAVDLVVENPEIGALIITGGGDRAFVAGADISELATLG
DVYAGRELALAGQDVMHQISSLPIPVIAAVNGFALGGGLELALACDVRVAAPNAKLGLPEVTLGLIPGFGGTQRLARLIG
AGRALDLMLTARQVSAEEALALGLVNYVADDPLMKAREVAEQMLKNAPIALSLVKEAVRRGLDTTLEAGLEVEADLFGMA
VATQDFREGTSAFLAKRRPAFKGE

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=39.3700787401575, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI4502327, Length=271, Percent_Identity=38.7453874538745, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI68989263, Length=278, Percent_Identity=33.8129496402878, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=34.2391304347826, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI157694516, Length=225, Percent_Identity=30.6666666666667, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI213417737, Length=225, Percent_Identity=30.6666666666667, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI150378541, Length=267, Percent_Identity=30.7116104868914, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI157694520, Length=195, Percent_Identity=32.3076923076923, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI70995211, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=28.4552845528455, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI261878539, Length=180, Percent_Identity=36.1111111111111, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI37594469, Length=186, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI37594471, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=42.1686746987952, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=36.1538461538462, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=43.6170212765958, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788597, Length=253, Percent_Identity=34.3873517786561, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=36, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=36.2244897959184, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082183, Length=265, Percent_Identity=31.3207547169811, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=40.4, Blast_Score=185, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=41.2955465587045, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17540714, Length=220, Percent_Identity=38.1818181818182, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17558304, Length=240, Percent_Identity=32.9166666666667, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17560910, Length=246, Percent_Identity=30.4878048780488, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25144276, Length=179, Percent_Identity=38.5474860335196, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508953, Length=179, Percent_Identity=38.5474860335196, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508951, Length=179, Percent_Identity=38.5474860335196, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=31.496062992126, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536985, Length=256, Percent_Identity=28.515625, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144157, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=256, Percent_Identity=30.859375, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25141363, Length=163, Percent_Identity=29.4478527607362, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=203, Percent_Identity=28.0788177339901, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=24.0157480314961, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=186, Percent_Identity=28.494623655914, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=40, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=40, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=36.1111111111111, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19920382, Length=271, Percent_Identity=28.4132841328413, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19921000, Length=197, Percent_Identity=37.0558375634518, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583077, Length=197, Percent_Identity=37.0558375634518, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24583079, Length=197, Percent_Identity=37.0558375634518, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=24.8031496062992, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357171, Length=182, Percent_Identity=31.3186813186813, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583165, Length=247, Percent_Identity=30.3643724696356, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571730, Length=190, Percent_Identity=29.4736842105263, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571729, Length=190, Percent_Identity=29.4736842105263, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650670, Length=186, Percent_Identity=31.7204301075269, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19921018, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654903, Length=183, Percent_Identity=26.775956284153, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550169, Length=255, Percent_Identity=27.843137254902, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27725; Mature: 27594

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLDELEFRNLHLDQHGPLAVLTVSRPKALNALNADTLSEIAQAVDLVVENPEIGALII
CCCHHHCCHHHEECCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEE
TGGGDRAFVAGADISELATLGDVYAGRELALAGQDVMHQISSLPIPVIAAVNGFALGGGL
ECCCCEEEEECCCHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEECCCCEEECCCE
ELALACDVRVAAPNAKLGLPEVTLGLIPGFGGTQRLARLIGAGRALDLMLTARQVSAEEA
EEEEEEEEEEECCCCCCCCCHHHEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LALGLVNYVADDPLMKAREVAEQMLKNAPIALSLVKEAVRRGLDTTLEAGLEVEADLFGM
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCEECHHHHHH
AVATQDFREGTSAFLAKRRPAFKGE
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TMLDELEFRNLHLDQHGPLAVLTVSRPKALNALNADTLSEIAQAVDLVVENPEIGALII
CCHHHCCHHHEECCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEE
TGGGDRAFVAGADISELATLGDVYAGRELALAGQDVMHQISSLPIPVIAAVNGFALGGGL
ECCCCEEEEECCCHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEECCCCEEECCCE
ELALACDVRVAAPNAKLGLPEVTLGLIPGFGGTQRLARLIGAGRALDLMLTARQVSAEEA
EEEEEEEEEEECCCCCCCCCHHHEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LALGLVNYVADDPLMKAREVAEQMLKNAPIALSLVKEAVRRGLDTTLEAGLEVEADLFGM
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCEECHHHHHH
AVATQDFREGTSAFLAKRRPAFKGE
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]