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The map label for this gene is kdpD [H]

Identifier: 94985658

GI number: 94985658

Start: 1657272

End: 1658519

Strand: Reverse

Name: kdpD [H]

Synonym: Dgeo_1558

Alternate gene names: 94985658

Gene position: 1658519-1657272 (Counterclockwise)

Preceding gene: 94985659

Following gene: 94985654

Centisome position: 67.22

GC content: 69.39

Gene sequence:

>1248_bases
GTGACGTCCGTGCCCCCGGTGTCTTGGTGGATCCGGCTGCGCGAGGTGGTGCTGGCCGCGTTGCCCGCCGTGCTCACCGT
CGTGCTGCTGCTGCTTGCGACGCAACCGGCCTACGAGACGCTGATCCGCAATGGGAACGGCTGGACGCCCTATGCCTACC
AGGCCCTCGCGCAGGACGTGCTGGCCTACCAGGTGGCCCAGCTGGACCCTAGGCAAGGGGGCGGGCAACGGCAGATGAAG
TACGAGATGGCCCTCTCCAGTGCGGCCAACCCGGGCCAATTCACGATGTTGCCGGCGGTGGAGGCTCACGGCGACGCGCG
GTTGGCACGGATCGAGGCGCTGCTGCGGCAAAACACGGCCGCCAGCATCGCGGAGGCCGCCCGTGAGGCGATCCGGCTCA
ATGCTCAGGCGGGGGACTTTGCCAACGAAACGCGGGTGCAGTACGTGCAGGCGCTCGAAGCGATGCGCCGCGCTCTGATC
GGCACCGCGCTCATCACCGGCATCCTCAGCATGCTGCTGACCGTGCGAGCACTGCTGCTGTGGCGCGCCGAACGCGAACG
CCGCTCTCGCCGAGAAGCCCGCCAGCGCGAGGCGCTGAGCCTCGCCAGCCACGAACTGCGCCGCCCCCTACAGGCGCTGC
TGTTTGCCAGCGATCTGCTCCGCCAGGCCGACACCCCCGAGCAGCGCGAACACCTGCTCAGCCTGATCGAAGACAGCACC
GCCCAGCTCGCCAGCCGCGCCGACCTGACGAACCTGCAGGATCTGTACATGGACGTGAACTTGCGCCTGACCCGCCCCGA
CCTGCGCCCACTGGTGCAGCGGGCAGCCGGAGGGCGGGTGCGCGTCCAGGTGCCCGCGGAACCGGTGCTCTGGCCAGTGG
ATGTGGACCGCCTGCGCCAGATCATCGAGAATCTGGTCGAGAATGCCCTGAAGTACACCTCCGGCCCAGTGGAGGTGGCG
CTCGCCACGCCCGGCGGGCGGCCCACAATCACCGTGCGCGACTTCGGCCCCGGCATTCCCATTGACCTGCGCGAGCGAGT
CTTTCTGCCCTATGAACGCGGGTCACACGCTCCAGCGCAGGGTCAGGGCCTGGGCTTGCCCCTGGTGCGCCGCTATGCCC
GTGCCCACGGTGGAGACGTGACCCTGGAAGACGCGCCAGGCGGCGGCACGCTGGCTCGCCTCACCCTGGGCGAGCCGCCG
CGACCGGAAAAGGGACAGGACACGCCAAAAGGGCGGGAAACACGCTGA

Upstream 100 bases:

>100_bases
GACCGCTGACGGTGGTGTTGCCCCCTGATCCGCAGCGCTTCCCGGCGCGGCTGTATGGAGCCGCCTGGGTGTGGTACGTC
GAGCGCATCACCCCGGCGCC

Downstream 100 bases:

>100_bases
GAGGTCCTGAAGCCTACTCGGCGGGCGTGGCGAACACCTGGGTCCAGTAGCGCAGGTACGGGCTGTCCTGACGGTACACG
TACGACACGCCCACGCGGGT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTSVPPVSWWIRLREVVLAALPAVLTVVLLLLATQPAYETLIRNGNGWTPYAYQALAQDVLAYQVAQLDPRQGGGQRQMK
YEMALSSAANPGQFTMLPAVEAHGDARLARIEALLRQNTAASIAEAAREAIRLNAQAGDFANETRVQYVQALEAMRRALI
GTALITGILSMLLTVRALLLWRAERERRSRREARQREALSLASHELRRPLQALLFASDLLRQADTPEQREHLLSLIEDST
AQLASRADLTNLQDLYMDVNLRLTRPDLRPLVQRAAGGRVRVQVPAEPVLWPVDVDRLRQIIENLVENALKYTSGPVEVA
LATPGGRPTITVRDFGPGIPIDLRERVFLPYERGSHAPAQGQGLGLPLVRRYARAHGGDVTLEDAPGGGTLARLTLGEPP
RPEKGQDTPKGRETR

Sequences:

>Translated_415_residues
MTSVPPVSWWIRLREVVLAALPAVLTVVLLLLATQPAYETLIRNGNGWTPYAYQALAQDVLAYQVAQLDPRQGGGQRQMK
YEMALSSAANPGQFTMLPAVEAHGDARLARIEALLRQNTAASIAEAAREAIRLNAQAGDFANETRVQYVQALEAMRRALI
GTALITGILSMLLTVRALLLWRAERERRSRREARQREALSLASHELRRPLQALLFASDLLRQADTPEQREHLLSLIEDST
AQLASRADLTNLQDLYMDVNLRLTRPDLRPLVQRAAGGRVRVQVPAEPVLWPVDVDRLRQIIENLVENALKYTSGPVEVA
LATPGGRPTITVRDFGPGIPIDLRERVFLPYERGSHAPAQGQGLGLPLVRRYARAHGGDVTLEDAPGGGTLARLTLGEPP
RPEKGQDTPKGRETR
>Mature_414_residues
TSVPPVSWWIRLREVVLAALPAVLTVVLLLLATQPAYETLIRNGNGWTPYAYQALAQDVLAYQVAQLDPRQGGGQRQMKY
EMALSSAANPGQFTMLPAVEAHGDARLARIEALLRQNTAASIAEAAREAIRLNAQAGDFANETRVQYVQALEAMRRALIG
TALITGILSMLLTVRALLLWRAERERRSRREARQREALSLASHELRRPLQALLFASDLLRQADTPEQREHLLSLIEDSTA
QLASRADLTNLQDLYMDVNLRLTRPDLRPLVQRAAGGRVRVQVPAEPVLWPVDVDRLRQIIENLVENALKYTSGPVEVAL
ATPGGRPTITVRDFGPGIPIDLRERVFLPYERGSHAPAQGQGLGLPLVRRYARAHGGDVTLEDAPGGGTLARLTLGEPPR
PEKGQDTPKGRETR

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=29.8165137614679, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=32.4074074074074, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=29.6, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=28.9156626506024, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=28.6919831223629, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=31.858407079646, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45771; Mature: 45640

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPPVSWWIRLREVVLAALPAVLTVVLLLLATQPAYETLIRNGNGWTPYAYQALAQDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LAYQVAQLDPRQGGGQRQMKYEMALSSAANPGQFTMLPAVEAHGDARLARIEALLRQNTA
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHCCCCHHHHHHHHHHHHCHH
ASIAEAAREAIRLNAQAGDFANETRVQYVQALEAMRRALIGTALITGILSMLLTVRALLL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAERERRSRREARQREALSLASHELRRPLQALLFASDLLRQADTPEQREHLLSLIEDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQLASRADLTNLQDLYMDVNLRLTRPDLRPLVQRAAGGRVRVQVPAEPVLWPVDVDRLRQ
HHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHH
IIENLVENALKYTSGPVEVALATPGGRPTITVRDFGPGIPIDLRERVFLPYERGSHAPAQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCCCCCC
GQGLGLPLVRRYARAHGGDVTLEDAPGGGTLARLTLGEPPRPEKGQDTPKGRETR
CCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSVPPVSWWIRLREVVLAALPAVLTVVLLLLATQPAYETLIRNGNGWTPYAYQALAQDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LAYQVAQLDPRQGGGQRQMKYEMALSSAANPGQFTMLPAVEAHGDARLARIEALLRQNTA
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHCCCCHHHHHHHHHHHHCHH
ASIAEAAREAIRLNAQAGDFANETRVQYVQALEAMRRALIGTALITGILSMLLTVRALLL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAERERRSRREARQREALSLASHELRRPLQALLFASDLLRQADTPEQREHLLSLIEDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQLASRADLTNLQDLYMDVNLRLTRPDLRPLVQRAAGGRVRVQVPAEPVLWPVDVDRLRQ
HHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHH
IIENLVENALKYTSGPVEVALATPGGRPTITVRDFGPGIPIDLRERVFLPYERGSHAPAQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCCCCCC
GQGLGLPLVRRYARAHGGDVTLEDAPGGGTLARLTLGEPPRPEKGQDTPKGRETR
CCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]