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The map label for this gene is argD [H]

Identifier: 94985516

GI number: 94985516

Start: 1502209

End: 1503456

Strand: Reverse

Name: argD [H]

Synonym: Dgeo_1416

Alternate gene names: 94985516

Gene position: 1503456-1502209 (Counterclockwise)

Preceding gene: 94985517

Following gene: 94985515

Centisome position: 60.94

GC content: 65.14

Gene sequence:

>1248_bases
ATGACGGGCACGAAGACCAAGGCAAGCAAGTGGCTTGACGCCGAGCTGCGCTACGACTCTGGCGTCTACAACAAGCATCA
GGTCGTGATGGTGCGCGGTCAGGGCGCGACTGTGTGGGACGAGACGGGCCGGGCCTACATCGACTGTGTGGCCGGGTACG
GCGTGGCCAACATCGGTCACTGCCATCCCGACGTGGTGAAAGCCATTCAGGAACAGGCCGCTCGCCTGATCGTGATGCCG
CAGACTCTCCCCAACGACAAACGAGCTGAGTTCCTGACCGAGCTGGTGGGCGTGCTGCCGCAGGGCTTAGAGCGCGTCTT
CCTCTGCAACTCCGGCACCGAGGCGATGGAGGCGGCCAAGAAGTTCGCCATCACCGCGACGGGCCGTTCCCGCTTCGTGA
GCATGAAACGCGGCTTTTCGGGCCGTTCGCTCGGCGCGCTCGCCTTTACCTGGGAACCCAAGTACCGCGAGCCGTTCGGC
GAGGCGGTGGACAACAAGCACGTGGACTTTGTGACCTACGGGAATATCGACGAGCTGCGCGCAGCGGTCACCGATCAGAC
TGCCGCCGTGATTTTGGAGCCGGTGCAGGGCGAGGGCGGTGTGCGGCCCGTGACGCCTGAGTTCATTCGGGCGGCGCGCG
AGATCACCCGCGAAAAGGGTGCACTCCTGATCCTCGACGAGATCCAAACGGGTTTTTGCCGCACGGGCAAGATGTTCGCC
GCCGAGCATTTCGGCGTGGTCCCGGACGGCATGACCCTCGCCAAGGCGATGGCGGGCGGCGTGCCGGTCGGGGCCTTTGC
CATGACGGCGGAGGTTGCGGACCGGATGCCCGCAGGGGGACACGGCACCACCTTTGGCGGGAATCCGCTGGCGATGGCCG
CCGGCATCGCTGCTATTCGTGCCATGAAGAACGAGAAGATGGCCGAGCAGGCCCGCGAGAAGGGCGCGTATTTCATGGAG
CGGCTGCGCGCCATCCGCTCTCCCAAAATCCGCGAGGTTCGCGGGCTGGGCCTGATGATCGGCGTGGAACTCAAGGAAAA
AAGCGCCCCCTACATCGCGGCCCTCGAACATGAGGAGGGTGTGCTGACCCTCGCCGCGACGCCGCTCGTTGTTCGCTTCC
TGCCGCCCCTCACCATCAGCCGGGAGCAGATCGATCAGGTGGTGGCCGCCTTCGAACGCGTCCTGGAAAGGGTTAACCCC
CGCGCGATCCCGAACCAGGAGCTGCGGGAAGACAAGCAGACGGAGTGA

Upstream 100 bases:

>100_bases
GCCCAGGGCCTGATGCTGTCCTGCCTCGCCCGCCCGCTTCTGATCCGCCCGGCTGGACACGCCGCCCCGTTTCCTCATCC
TTACCCCTACACTAGGGTCC

Downstream 100 bases:

>100_bases
TACGGGATTGCTGGGAGTTCAATCGCTATCGGGGCCATCTTTGACTCGCTTGAAGTTCGTATGAGCGAGGACGCGGGAGG
ACGCACCCTTCCCGCGTCCA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTGTKTKASKWLDAELRYDSGVYNKHQVVMVRGQGATVWDETGRAYIDCVAGYGVANIGHCHPDVVKAIQEQAARLIVMP
QTLPNDKRAEFLTELVGVLPQGLERVFLCNSGTEAMEAAKKFAITATGRSRFVSMKRGFSGRSLGALAFTWEPKYREPFG
EAVDNKHVDFVTYGNIDELRAAVTDQTAAVILEPVQGEGGVRPVTPEFIRAAREITREKGALLILDEIQTGFCRTGKMFA
AEHFGVVPDGMTLAKAMAGGVPVGAFAMTAEVADRMPAGGHGTTFGGNPLAMAAGIAAIRAMKNEKMAEQAREKGAYFME
RLRAIRSPKIREVRGLGLMIGVELKEKSAPYIAALEHEEGVLTLAATPLVVRFLPPLTISREQIDQVVAAFERVLERVNP
RAIPNQELREDKQTE

Sequences:

>Translated_415_residues
MTGTKTKASKWLDAELRYDSGVYNKHQVVMVRGQGATVWDETGRAYIDCVAGYGVANIGHCHPDVVKAIQEQAARLIVMP
QTLPNDKRAEFLTELVGVLPQGLERVFLCNSGTEAMEAAKKFAITATGRSRFVSMKRGFSGRSLGALAFTWEPKYREPFG
EAVDNKHVDFVTYGNIDELRAAVTDQTAAVILEPVQGEGGVRPVTPEFIRAAREITREKGALLILDEIQTGFCRTGKMFA
AEHFGVVPDGMTLAKAMAGGVPVGAFAMTAEVADRMPAGGHGTTFGGNPLAMAAGIAAIRAMKNEKMAEQAREKGAYFME
RLRAIRSPKIREVRGLGLMIGVELKEKSAPYIAALEHEEGVLTLAATPLVVRFLPPLTISREQIDQVVAAFERVLERVNP
RAIPNQELREDKQTE
>Mature_414_residues
TGTKTKASKWLDAELRYDSGVYNKHQVVMVRGQGATVWDETGRAYIDCVAGYGVANIGHCHPDVVKAIQEQAARLIVMPQ
TLPNDKRAEFLTELVGVLPQGLERVFLCNSGTEAMEAAKKFAITATGRSRFVSMKRGFSGRSLGALAFTWEPKYREPFGE
AVDNKHVDFVTYGNIDELRAAVTDQTAAVILEPVQGEGGVRPVTPEFIRAAREITREKGALLILDEIQTGFCRTGKMFAA
EHFGVVPDGMTLAKAMAGGVPVGAFAMTAEVADRMPAGGHGTTFGGNPLAMAAGIAAIRAMKNEKMAEQAREKGAYFMER
LRAIRSPKIREVRGLGLMIGVELKEKSAPYIAALEHEEGVLTLAATPLVVRFLPPLTISREQIDQVVAAFERVLERVNPR
AIPNQELREDKQTE

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=31.077694235589, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=30.3529411764706, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=29.8076923076923, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13994255, Length=362, Percent_Identity=29.2817679558011, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=31.1036789297659, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=28.6057692307692, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.2746113989637, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=24.3498817966903, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=24.3498817966903, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=24.3498817966903, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=38.7755102040816, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=36.2244897959184, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI145693181, Length=382, Percent_Identity=39.7905759162304, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=34.6633416458853, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=34.7826086956522, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1786991, Length=402, Percent_Identity=33.0845771144279, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786349, Length=296, Percent_Identity=35.1351351351351, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=32.133676092545, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=29.1764705882353, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=388, Percent_Identity=28.8659793814433, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=25.8823529411765, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=26.6514806378132, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=180, Percent_Identity=29.4444444444444, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=391, Percent_Identity=35.2941176470588, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=31.1778290993072, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=416, Percent_Identity=24.0384615384615, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=361, Percent_Identity=25.207756232687, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=31.2020460358056, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=28.9592760180996, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=30.2439024390244, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=30.1435406698565, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=25.1173708920188, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=25.1173708920188, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=25.1173708920188, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45229; Mature: 45098

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTKTKASKWLDAELRYDSGVYNKHQVVMVRGQGATVWDETGRAYIDCVAGYGVANIGH
CCCCCCCHHHCCCCEEECCCCCCCCEEEEEEECCCCEEECCCCCEEEEHHHCCCCCCCCC
CHPDVVKAIQEQAARLIVMPQTLPNDKRAEFLTELVGVLPQGLERVFLCNSGTEAMEAAK
CCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
KFAITATGRSRFVSMKRGFSGRSLGALAFTWEPKYREPFGEAVDNKHVDFVTYGNIDELR
HEEEEECCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEECCHHHHH
AAVTDQTAAVILEPVQGEGGVRPVTPEFIRAAREITREKGALLILDEIQTGFCRTGKMFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHH
AEHFGVVPDGMTLAKAMAGGVPVGAFAMTAEVADRMPAGGHGTTFGGNPLAMAAGIAAIR
HHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AMKNEKMAEQAREKGAYFMERLRAIRSPKIREVRGLGLMIGVELKEKSAPYIAALEHEEG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCEEEEEECCCC
VLTLAATPLVVRFLPPLTISREQIDQVVAAFERVLERVNPRAIPNQELREDKQTE
EEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TGTKTKASKWLDAELRYDSGVYNKHQVVMVRGQGATVWDETGRAYIDCVAGYGVANIGH
CCCCCCHHHCCCCEEECCCCCCCCEEEEEEECCCCEEECCCCCEEEEHHHCCCCCCCCC
CHPDVVKAIQEQAARLIVMPQTLPNDKRAEFLTELVGVLPQGLERVFLCNSGTEAMEAAK
CCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
KFAITATGRSRFVSMKRGFSGRSLGALAFTWEPKYREPFGEAVDNKHVDFVTYGNIDELR
HEEEEECCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEECCHHHHH
AAVTDQTAAVILEPVQGEGGVRPVTPEFIRAAREITREKGALLILDEIQTGFCRTGKMFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHH
AEHFGVVPDGMTLAKAMAGGVPVGAFAMTAEVADRMPAGGHGTTFGGNPLAMAAGIAAIR
HHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AMKNEKMAEQAREKGAYFMERLRAIRSPKIREVRGLGLMIGVELKEKSAPYIAALEHEEG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCEEEEEECCCC
VLTLAATPLVVRFLPPLTISREQIDQVVAAFERVLERVNPRAIPNQELREDKQTE
EEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]