Click here to switch to the map view.

The map label for this gene is yajO [H]

Identifier: 94985502

GI number: 94985502

Start: 1486912

End: 1487868

Strand: Reverse

Name: yajO [H]

Synonym: Dgeo_1402

Alternate gene names: 94985502

Gene position: 1487868-1486912 (Counterclockwise)

Preceding gene: 94985504

Following gene: 94985500

Centisome position: 60.31

GC content: 66.98

Gene sequence:

>957_bases
ATGCAGTTTGGCTGGACAGCGGATGAGGCGACGGCCTTCGAGCTGATGGACGCCTACCGTGCGGCGGGCGGAAATTTTAT
CGACACGGCGGATATCTACAGCAACTGGGTGCCCGGCAATCCCGGCGGGGTGTCCGAGGAAATCGTGGGGCGTTGGCTGA
AATCGCGCGGGAGCCGAGATGAGATGGTCATCGCGACCAAGGTGCGCGGGCCAATGGGCGAGGGGGGGCGCGAGGGGCGG
GACAGCATCCACCAGCGCGAGGGTCTCTCGCGGCGCTGGATTCTCAAGGCCTGCGAGGACAGCCTGCGGCGGTTGGGGGT
GGACCACATCGACCTCTACCAGGCGCACTGGGTGGACAACCGGACGCCCATCGAGGAGACGTTGGAGGCCTTCACTGAAC
TCGTGAAGCGCGGGTACGTGCGCTACATCGGGGCGTCGAACTACTCGGCGTGGCGGCTGATGCAGGCGCTGTGGACAAGT
GACAAGAAGGGCCTGGAGAGCTTTGTCAGTCTGCAACCCGAGTACAGCCTCCTCTCGCCCACGCGGGCCAACTTCGAGCG
TGAGCTTTCGCGGGTATGCGTGGAGTACGGCCTGGGGGTGATTCCCTGGAGTCCGCTGGGAGGTGGGATGTTGACCGGGA
AATACAAGCGCGGTCAGCCCCTCCCCGAGAGCGTGCGGGCGAACGAGAACGCGGCGCGGCGCTTCAGCGACAAGAACTTC
GACATCGTCGAGACGCTGGAGGCGGTCGCTGCTCGGCACGGGGCACGGCCCGCGCAGGTGGCCCTCGCGTGGCTGCTCGC
CCAGCCGGGTGTGACCGCGCCCATCATCGGGGCGAACAGCGTGGCCCAGCTCACCGAGTTGCTGGGGACCCTGAGCCTCA
CCCTGACGGAGGACGACCTGGCCGAGCTGAGCCGCGTGAGCGACTGGGAACGGGCGCGGACGGAGCTGGAGCGGTAA

Upstream 100 bases:

>100_bases
GCGCAGCGAGGGTGGCGAGGACGCTACCCTGTCGCCCATGACCTCCTACCGCAGACTCGGTCGCAGCGGCCTGCGCCTCT
TTCCCCTGGGGCTTGGCTCC

Downstream 100 bases:

>100_bases
AGCCCCCTCACCCCCGTCTTCCGCAGGAGACCTCGCCCCACGGCGAGCGGTTGTGCGGCTCAGGTCTCCGGGGCCGCCAT
GTCTGTCCCCTCCCCGTGTG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MQFGWTADEATAFELMDAYRAAGGNFIDTADIYSNWVPGNPGGVSEEIVGRWLKSRGSRDEMVIATKVRGPMGEGGREGR
DSIHQREGLSRRWILKACEDSLRRLGVDHIDLYQAHWVDNRTPIEETLEAFTELVKRGYVRYIGASNYSAWRLMQALWTS
DKKGLESFVSLQPEYSLLSPTRANFERELSRVCVEYGLGVIPWSPLGGGMLTGKYKRGQPLPESVRANENAARRFSDKNF
DIVETLEAVAARHGARPAQVALAWLLAQPGVTAPIIGANSVAQLTELLGTLSLTLTEDDLAELSRVSDWERARTELER

Sequences:

>Translated_318_residues
MQFGWTADEATAFELMDAYRAAGGNFIDTADIYSNWVPGNPGGVSEEIVGRWLKSRGSRDEMVIATKVRGPMGEGGREGR
DSIHQREGLSRRWILKACEDSLRRLGVDHIDLYQAHWVDNRTPIEETLEAFTELVKRGYVRYIGASNYSAWRLMQALWTS
DKKGLESFVSLQPEYSLLSPTRANFERELSRVCVEYGLGVIPWSPLGGGMLTGKYKRGQPLPESVRANENAARRFSDKNF
DIVETLEAVAARHGARPAQVALAWLLAQPGVTAPIIGANSVAQLTELLGTLSLTLTEDDLAELSRVSDWERARTELER
>Mature_318_residues
MQFGWTADEATAFELMDAYRAAGGNFIDTADIYSNWVPGNPGGVSEEIVGRWLKSRGSRDEMVIATKVRGPMGEGGREGR
DSIHQREGLSRRWILKACEDSLRRLGVDHIDLYQAHWVDNRTPIEETLEAFTELVKRGYVRYIGASNYSAWRLMQALWTS
DKKGLESFVSLQPEYSLLSPTRANFERELSRVCVEYGLGVIPWSPLGGGMLTGKYKRGQPLPESVRANENAARRFSDKNF
DIVETLEAVAARHGARPAQVALAWLLAQPGVTAPIIGANSVAQLTELLGTLSLTLTEDDLAELSRVSDWERARTELER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=300, Percent_Identity=30.6666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436964, Length=301, Percent_Identity=31.2292358803987, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436966, Length=301, Percent_Identity=31.2292358803987, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI27436969, Length=300, Percent_Identity=30, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI4504825, Length=300, Percent_Identity=30, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI27436971, Length=313, Percent_Identity=30.3514376996805, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI223718702, Length=217, Percent_Identity=32.7188940092166, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41152114, Length=307, Percent_Identity=28.9902280130293, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI41327764, Length=330, Percent_Identity=28.4848484848485, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081735, Length=300, Percent_Identity=41.3333333333333, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789199, Length=331, Percent_Identity=36.8580060422961, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1789375, Length=298, Percent_Identity=32.2147651006711, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788070, Length=292, Percent_Identity=33.2191780821918, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787674, Length=311, Percent_Identity=28.9389067524116, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=28.4745762711864, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=32.9305135951662, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319958, Length=308, Percent_Identity=30.1948051948052, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323998, Length=311, Percent_Identity=30.2250803858521, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=302, Percent_Identity=30.4635761589404, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=27.9693486590038, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321052, Length=127, Percent_Identity=39.3700787401575, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640980, Length=332, Percent_Identity=25, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45549126, Length=301, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553081, Length=309, Percent_Identity=25.8899676375405, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281366140, Length=319, Percent_Identity=25.3918495297806, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35445; Mature: 35445

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFGWTADEATAFELMDAYRAAGGNFIDTADIYSNWVPGNPGGVSEEIVGRWLKSRGSRD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
EMVIATKVRGPMGEGGREGRDSIHQREGLSRRWILKACEDSLRRLGVDHIDLYQAHWVDN
CEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
RTPIEETLEAFTELVKRGYVRYIGASNYSAWRLMQALWTSDKKGLESFVSLQPEYSLLSP
CCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCC
TRANFERELSRVCVEYGLGVIPWSPLGGGMLTGKYKRGQPLPESVRANENAARRFSDKNF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHCCCHHHHHHCCCCC
DIVETLEAVAARHGARPAQVALAWLLAQPGVTAPIIGANSVAQLTELLGTLSLTLTEDDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEECHHHH
AELSRVSDWERARTELER
HHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MQFGWTADEATAFELMDAYRAAGGNFIDTADIYSNWVPGNPGGVSEEIVGRWLKSRGSRD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
EMVIATKVRGPMGEGGREGRDSIHQREGLSRRWILKACEDSLRRLGVDHIDLYQAHWVDN
CEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
RTPIEETLEAFTELVKRGYVRYIGASNYSAWRLMQALWTSDKKGLESFVSLQPEYSLLSP
CCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCC
TRANFERELSRVCVEYGLGVIPWSPLGGGMLTGKYKRGQPLPESVRANENAARRFSDKNF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHCCCHHHHHHCCCCC
DIVETLEAVAARHGARPAQVALAWLLAQPGVTAPIIGANSVAQLTELLGTLSLTLTEDDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEECHHHH
AELSRVSDWERARTELER
HHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]