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The map label for this gene is lysK [H]

Identifier: 94985491

GI number: 94985491

Start: 1475204

End: 1476280

Strand: Reverse

Name: lysK [H]

Synonym: Dgeo_1391

Alternate gene names: 94985491

Gene position: 1476280-1475204 (Counterclockwise)

Preceding gene: 94985492

Following gene: 94985490

Centisome position: 59.84

GC content: 68.43

Gene sequence:

>1077_bases
ATGACCGAGGCGCCTGAGAAGATGGAGGCCCGCGACCTTGTCCGGGGTGCCGTGGCCATCCCCTCCGTCTCTGGGCAGGA
GGCGCAGGTGGCGGCCTTCCTCACGGATTGGATGACGGCACATGGCTTCCGCGCCCACATCGACGAGGCCGGGAATGCAG
TGGGCGAGCGCGGCAGTGGTCCGCTCACGGTGGTGCTGCTGGGCCACATCGACACCGTCCCGGGCGAGATTCCGGTCCGA
GTAGAAGGAGACCGGCTGTACGGGCGCGGCAGCGTGGACGCCAAGGGCAGCTTCTGCACCTTTGTGGCGGCGGTGGCGGC
TCTGCCCGAAACCGTCCTGCGCGGCGCGCGCTTCATCTGCATCGGCGCGACCGAGGAAGAGGTGCCCAGCAGCCGCGGCG
CTCGCTTTGCTCTACAGCGCTACCAGCCTGATCTGGTCCTGATTGGGGAGCCAAGCGGGTGGGCGGGCCTGACCCTGGGC
TACAAGGGCCGTCTGGTGGCGCAGGTCCGTGTCCGAAAAGACAACTTCCATACGGCGGGCGAGGGAACCAGCGCCGCCGA
TGATCTGGCGGAGGCGTGGTTTCGAGTGCGGGCCTGGGCTGCTCAGCACTCAGGGCATGGTGTCTTCGACGCGGTCCAGG
CGACCCTCCAGAGCCTCTCCACCCGCACCGACGGATTAAGCCAGCTCGCCGAGGGTACCTTCGGTCTGCGCCTTCCGCCG
CAGGTCTCCCCAGCTGTTGCCGAGACCGCCCTGCGAGACCGCCTGGCGGACCTGCCGGTCTCCCTCTCCTTCAGTGGCCA
CGAGACCGCGGTGCGTCATCCCAGAGACAATGCCTTGACACGTGCGCTGCGGGTGGCGATTCGCGAGCAGGGCGGCACTC
CAGTCTTTAAGGTCAAGACCGGGACCAGCGACATGAACGTGGTCGCCTCGGCCTGGCCGGTGCCGACCGTGGCCTACGGT
CCCGGCGACAGTGCCCTCGATCATACGCCGGACGAACACCTCGACCTCGCCGAGTATGACCGGGCGGTGGCGGTGCTGAC
GGCGGCCCTCACGCGGCTGGCCGGAGACGTCGCATAA

Upstream 100 bases:

>100_bases
ATCGCGTTGTTGGCGTTTGCCGACGTCACCCGCTTGCTGGTGTCGCTGGCGCGCGCGGTGGCGGAGAGCAGGATGGTCGA
CGCAGCCGGGAGCCGGAGCG

Downstream 100 bases:

>100_bases
AAAGACAAAGACACGGCTTGGTGCTCGCCCTGCGCGGGCGCGCTCAGGGAAGGGCCGTACTGAAGGGGAAAACACTCGCC
CTGCCTTGAGCGGTTCGGCG

Product: acetyl-lysine deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTEAPEKMEARDLVRGAVAIPSVSGQEAQVAAFLTDWMTAHGFRAHIDEAGNAVGERGSGPLTVVLLGHIDTVPGEIPVR
VEGDRLYGRGSVDAKGSFCTFVAAVAALPETVLRGARFICIGATEEEVPSSRGARFALQRYQPDLVLIGEPSGWAGLTLG
YKGRLVAQVRVRKDNFHTAGEGTSAADDLAEAWFRVRAWAAQHSGHGVFDAVQATLQSLSTRTDGLSQLAEGTFGLRLPP
QVSPAVAETALRDRLADLPVSLSFSGHETAVRHPRDNALTRALRVAIREQGGTPVFKVKTGTSDMNVVASAWPVPTVAYG
PGDSALDHTPDEHLDLAEYDRAVAVLTAALTRLAGDVA

Sequences:

>Translated_358_residues
MTEAPEKMEARDLVRGAVAIPSVSGQEAQVAAFLTDWMTAHGFRAHIDEAGNAVGERGSGPLTVVLLGHIDTVPGEIPVR
VEGDRLYGRGSVDAKGSFCTFVAAVAALPETVLRGARFICIGATEEEVPSSRGARFALQRYQPDLVLIGEPSGWAGLTLG
YKGRLVAQVRVRKDNFHTAGEGTSAADDLAEAWFRVRAWAAQHSGHGVFDAVQATLQSLSTRTDGLSQLAEGTFGLRLPP
QVSPAVAETALRDRLADLPVSLSFSGHETAVRHPRDNALTRALRVAIREQGGTPVFKVKTGTSDMNVVASAWPVPTVAYG
PGDSALDHTPDEHLDLAEYDRAVAVLTAALTRLAGDVA
>Mature_357_residues
TEAPEKMEARDLVRGAVAIPSVSGQEAQVAAFLTDWMTAHGFRAHIDEAGNAVGERGSGPLTVVLLGHIDTVPGEIPVRV
EGDRLYGRGSVDAKGSFCTFVAAVAALPETVLRGARFICIGATEEEVPSSRGARFALQRYQPDLVLIGEPSGWAGLTLGY
KGRLVAQVRVRKDNFHTAGEGTSAADDLAEAWFRVRAWAAQHSGHGVFDAVQATLQSLSTRTDGLSQLAEGTFGLRLPPQ
VSPAVAETALRDRLADLPVSLSFSGHETAVRHPRDNALTRALRVAIREQGGTPVFKVKTGTSDMNVVASAWPVPTVAYGP
GDSALDHTPDEHLDLAEYDRAVAVLTAALTRLAGDVA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=365, Percent_Identity=23.2876712328767, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010175
- InterPro:   IPR002933 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.-

Molecular weight: Translated: 37901; Mature: 37770

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAPEKMEARDLVRGAVAIPSVSGQEAQVAAFLTDWMTAHGFRAHIDEAGNAVGERGSG
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
PLTVVLLGHIDTVPGEIPVRVEGDRLYGRGSVDAKGSFCTFVAAVAALPETVLRGARFIC
CEEEEEEECCCCCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
IGATEEEVPSSRGARFALQRYQPDLVLIGEPSGWAGLTLGYKGRLVAQVRVRKDNFHTAG
EECCHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCCC
EGTSAADDLAEAWFRVRAWAAQHSGHGVFDAVQATLQSLSTRTDGLSQLAEGTFGLRLPP
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QVSPAVAETALRDRLADLPVSLSFSGHETAVRHPRDNALTRALRVAIREQGGTPVFKVKT
CCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
GTSDMNVVASAWPVPTVAYGPGDSALDHTPDEHLDLAEYDRAVAVLTAALTRLAGDVA
CCCCCEEEEECCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEAPEKMEARDLVRGAVAIPSVSGQEAQVAAFLTDWMTAHGFRAHIDEAGNAVGERGSG
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
PLTVVLLGHIDTVPGEIPVRVEGDRLYGRGSVDAKGSFCTFVAAVAALPETVLRGARFIC
CEEEEEEECCCCCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
IGATEEEVPSSRGARFALQRYQPDLVLIGEPSGWAGLTLGYKGRLVAQVRVRKDNFHTAG
EECCHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCCC
EGTSAADDLAEAWFRVRAWAAQHSGHGVFDAVQATLQSLSTRTDGLSQLAEGTFGLRLPP
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QVSPAVAETALRDRLADLPVSLSFSGHETAVRHPRDNALTRALRVAIREQGGTPVFKVKT
CCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEC
GTSDMNVVASAWPVPTVAYGPGDSALDHTPDEHLDLAEYDRAVAVLTAALTRLAGDVA
CCCCCEEEEECCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]