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The map label for this gene is gntK [H]

Identifier: 94972280

GI number: 94972280

Start: 211233

End: 212732

Strand: Direct

Name: gntK [H]

Synonym: Dgeo_2817

Alternate gene names: 94972280

Gene position: 211233-212732 (Clockwise)

Preceding gene: 94972281

Following gene: 94972279

Centisome position: 36.79

GC content: 67.73

Gene sequence:

>1500_bases
ATGACTGGGCAGCATTTCACGCAGCCGATGCGCACACCTCCGCCCGTGATGCTGAGCCTTGATTTGGGAAGCAGCGGACT
CAAAGGATCGGCCTTTGACACCCTGGGTCGCTCGCTGGCGGGGCTGGAGGCACATGCCCCAGTCGCGCTGCGCTATGCCC
CCGGCGGGGTCGCAGAGGTGGACCTTCCAGCGCTGATCCAGGGTATCGAAGAGATCCTCGACCGACTACACCAGCGGCTG
GGTCAGCGGCCAGTGCTGGGTGTGGCGCTGACCAGCTTTGTGAGCAGTCTGGTTGCGCTGGATACCGCTGACCGGCCGAT
TGGCCCGGTGCTTTCCTATGCCGATACCCGTTCGGCCGGCGAGGTGGCCGCCGTCGCGCGGCGGGTGGATCCCGAACAGG
TCGGGTGCCCCGCCTTCAGCGCCTACTGGCCCGCCCAGATCCGCTGGTGGCAGGCAGCCCATCCCCACCTCCACGCCGCA
CGCTATTGCAGCGTGCCTGATTATCTGCTGCGGCGCTGGACCGGTGCGTGGGTGACCAGTTACTCGTTGGCATCGTGGAC
TGGAATGCTAGACCGCTTCAGCCTGAGCTGGAACGCGGAGGCACTGGCCGCCGCCGAGGTGAGGGCCGACCAATTGCCCG
AGTTGGCGGACTACGACCTCGCCTTTTCCCTGCGCCCAGAATTCCAAGCCCGTTGGCCAAAACTGGCGCATGTTCCCTTT
TATCTGGGGGTTTCCGACGGCGCGACGGCAACGGTGGGAAGTGGCGCCCTCCTGCCCGGCCGCTTCGCCCTGACGGTCGG
CAGTACCAGTGCCGTTCGGATGGCCCTCACGGGGCCACCTCCAGCGATTCCGCCGGGCTTGTGGTCGTACCGCATCACGC
GGGAGATCCACCTTCTGGGCGGCGCGCTGACCGAGGGGGGCAATCTCTACAGCTGGCTAACCTCTACGCTGCAGCTGGGC
GGCAAGGAGCTCGAAGAAGAACTGCTGGGCATTGCGCCCGACAGCCACGGTCTTACCTTTATTCCCTCCTTGGGCGGCAC
CCGTAGTCCGGATTATGACCCGCACGCACGCGGCACAGTGCACGGCCTGAGCTATGCCACCACACCCGCACAGATCGCCC
GTGCCGGGATGGAGGGGGTGGCCTGCCGCCTGGCTGACCTGGCCTGGCGCCTCCCCATCACCGATGACGCCGTGTTTATC
GCCAGCGGCAAGGCGCTGCTGGCCTCACGCCCCTGGCAGCAGATGCTGGCCGATGCCCTGGGGCGTCCTTTGCTGCTGGA
AGACCGCCCGGCTGGGGCGAGCGCGCGCGGCGCAGCCCTGCTGGCGCTGGCCGCCCAGGGCCATCCTCTTCCCACCGAGC
CGGCCGCGCAGCGCCTGGTGGAACCGGTGCCCGACCATCACGAGCTGTACCGAGCGGCCACCCAGCGGATGCGGGTCCTG
GGAGCCGCGTTGGACAGGTTGCGAAAGGCGCAGGAGGTGCCCACATGCGACCCCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCGCCGCCGCCGTCCTGATTACGCTGCCGATTATCCTACTCTCCTTGACGGTACAAAAATACATCGTCAAGGGGCTG
ACTGCGGGTGGCGTAAAAGG

Downstream 100 bases:

>100_bases
CCGACGTGCTGGCTGCTGACCGCCTGCTGCCCCTCTTTACACCGGAGCCAGGAGAGACGGCAGCTAGGCGCCTGACAATT
CTGAAGCGAGCTGGGATCCG

Product: carbohydrate kinase, FGGY

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTGQHFTQPMRTPPPVMLSLDLGSSGLKGSAFDTLGRSLAGLEAHAPVALRYAPGGVAEVDLPALIQGIEEILDRLHQRL
GQRPVLGVALTSFVSSLVALDTADRPIGPVLSYADTRSAGEVAAVARRVDPEQVGCPAFSAYWPAQIRWWQAAHPHLHAA
RYCSVPDYLLRRWTGAWVTSYSLASWTGMLDRFSLSWNAEALAAAEVRADQLPELADYDLAFSLRPEFQARWPKLAHVPF
YLGVSDGATATVGSGALLPGRFALTVGSTSAVRMALTGPPPAIPPGLWSYRITREIHLLGGALTEGGNLYSWLTSTLQLG
GKELEEELLGIAPDSHGLTFIPSLGGTRSPDYDPHARGTVHGLSYATTPAQIARAGMEGVACRLADLAWRLPITDDAVFI
ASGKALLASRPWQQMLADALGRPLLLEDRPAGASARGAALLALAAQGHPLPTEPAAQRLVEPVPDHHELYRAATQRMRVL
GAALDRLRKAQEVPTCDPA

Sequences:

>Translated_499_residues
MTGQHFTQPMRTPPPVMLSLDLGSSGLKGSAFDTLGRSLAGLEAHAPVALRYAPGGVAEVDLPALIQGIEEILDRLHQRL
GQRPVLGVALTSFVSSLVALDTADRPIGPVLSYADTRSAGEVAAVARRVDPEQVGCPAFSAYWPAQIRWWQAAHPHLHAA
RYCSVPDYLLRRWTGAWVTSYSLASWTGMLDRFSLSWNAEALAAAEVRADQLPELADYDLAFSLRPEFQARWPKLAHVPF
YLGVSDGATATVGSGALLPGRFALTVGSTSAVRMALTGPPPAIPPGLWSYRITREIHLLGGALTEGGNLYSWLTSTLQLG
GKELEEELLGIAPDSHGLTFIPSLGGTRSPDYDPHARGTVHGLSYATTPAQIARAGMEGVACRLADLAWRLPITDDAVFI
ASGKALLASRPWQQMLADALGRPLLLEDRPAGASARGAALLALAAQGHPLPTEPAAQRLVEPVPDHHELYRAATQRMRVL
GAALDRLRKAQEVPTCDPA
>Mature_498_residues
TGQHFTQPMRTPPPVMLSLDLGSSGLKGSAFDTLGRSLAGLEAHAPVALRYAPGGVAEVDLPALIQGIEEILDRLHQRLG
QRPVLGVALTSFVSSLVALDTADRPIGPVLSYADTRSAGEVAAVARRVDPEQVGCPAFSAYWPAQIRWWQAAHPHLHAAR
YCSVPDYLLRRWTGAWVTSYSLASWTGMLDRFSLSWNAEALAAAEVRADQLPELADYDLAFSLRPEFQARWPKLAHVPFY
LGVSDGATATVGSGALLPGRFALTVGSTSAVRMALTGPPPAIPPGLWSYRITREIHLLGGALTEGGNLYSWLTSTLQLGG
KELEEELLGIAPDSHGLTFIPSLGGTRSPDYDPHARGTVHGLSYATTPAQIARAGMEGVACRLADLAWRLPITDDAVFIA
SGKALLASRPWQQMLADALGRPLLLEDRPAGASARGAALLALAAQGHPLPTEPAAQRLVEPVPDHHELYRAATQRMRVLG
AALDRLRKAQEVPTCDPA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=403, Percent_Identity=21.3399503722084, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789987, Length=450, Percent_Identity=27.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535599, Length=412, Percent_Identity=23.0582524271845, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321755, Length=328, Percent_Identity=26.219512195122, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 53358; Mature: 53227

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQHFTQPMRTPPPVMLSLDLGSSGLKGSAFDTLGRSLAGLEAHAPVALRYAPGGVAEV
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DLPALIQGIEEILDRLHQRLGQRPVLGVALTSFVSSLVALDTADRPIGPVLSYADTRSAG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCH
EVAAVARRVDPEQVGCPAFSAYWPAQIRWWQAAHPHLHAARYCSVPDYLLRRWTGAWVTS
HHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHCCCHHHH
YSLASWTGMLDRFSLSWNAEALAAAEVRADQLPELADYDLAFSLRPEFQARWPKLAHVPF
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCEECCEE
YLGVSDGATATVGSGALLPGRFALTVGSTSAVRMALTGPPPAIPPGLWSYRITREIHLLG
EEECCCCCCEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCEEHHHEEEEEC
GALTEGGNLYSWLTSTLQLGGKELEEELLGIAPDSHGLTFIPSLGGTRSPDYDPHARGTV
CHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
HGLSYATTPAQIARAGMEGVACRLADLAWRLPITDDAVFIASGKALLASRPWQQMLADAL
CCCCCCCCHHHHHHHCHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHCCCHHHHHHHHC
GRPLLLEDRPAGASARGAALLALAAQGHPLPTEPAAQRLVEPVPDHHELYRAATQRMRVL
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHH
GAALDRLRKAQEVPTCDPA
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGQHFTQPMRTPPPVMLSLDLGSSGLKGSAFDTLGRSLAGLEAHAPVALRYAPGGVAEV
CCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DLPALIQGIEEILDRLHQRLGQRPVLGVALTSFVSSLVALDTADRPIGPVLSYADTRSAG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCH
EVAAVARRVDPEQVGCPAFSAYWPAQIRWWQAAHPHLHAARYCSVPDYLLRRWTGAWVTS
HHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHCCCHHHH
YSLASWTGMLDRFSLSWNAEALAAAEVRADQLPELADYDLAFSLRPEFQARWPKLAHVPF
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCEECCEE
YLGVSDGATATVGSGALLPGRFALTVGSTSAVRMALTGPPPAIPPGLWSYRITREIHLLG
EEECCCCCCEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCEEHHHEEEEEC
GALTEGGNLYSWLTSTLQLGGKELEEELLGIAPDSHGLTFIPSLGGTRSPDYDPHARGTV
CHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
HGLSYATTPAQIARAGMEGVACRLADLAWRLPITDDAVFIASGKALLASRPWQQMLADAL
CCCCCCCCHHHHHHHCHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHCCCHHHHHHHHC
GRPLLLEDRPAGASARGAALLALAAQGHPLPTEPAAQRLVEPVPDHHELYRAATQRMRVL
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHH
GAALDRLRKAQEVPTCDPA
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]