Click here to switch to the map view.

The map label for this gene is iolC [H]

Identifier: 94972278

GI number: 94972278

Start: 213342

End: 214286

Strand: Direct

Name: iolC [H]

Synonym: Dgeo_2815

Alternate gene names: 94972278

Gene position: 213342-214286 (Clockwise)

Preceding gene: 94972279

Following gene: 94972277

Centisome position: 37.16

GC content: 66.46

Gene sequence:

>945_bases
ATGGCTGAAGCCCCCACGAGCGTTCTGACCTTTGGGGAAGCCCTGCTGAAATTGGTTCTGCTCCCCACTCAACGGTTGGA
GAGCATGCAGACCCTAGACGCGCAGTGTGCTGGGGCTGAGCTCAACGTTGCCGCCGCGCTCGCCGCCCTAGGTCGCCCAG
CAGCGTGGGTCAGCGCTCTGCCCGCTGGTCCGCTGGGCACATGGGTGCGGGAACGAGTACGTGCCCTCAAGGTCGACGAT
CTGGCCCTGACTCGGGAGGGCCGTTTGGGAACGTTCTACCTCGAAGACCACCACCCACCCCGTCCCAGCCGAGTGGTGTA
TGACCGCCGCGGCAGCGCCTTTACACAACTGAACGCGGCCGACTTCGATCCGGCCTGGCTGGCGGGCCGGCGAGCGCTGC
ATGTCAGTGGCATCAGCCTGGCGGTGGGACAGGGACCGCGTGACCTCGCACTCAAGCTGATGTGGGAGGCCCGACAGGCA
GGCGTCGTCATCAGTTTCGACGTCAATCACCGTCGCCTGTTGCTGGCTGAGGATGCGGCCCGAGAGCTTTACACCCCGGC
CCTGCGCCTGGCCGACCTGATCTTTGTCGCCGAACGTGACACGCCGCTGCTGGGTGGTCTGACGGGCCTGCGGAGCCTCG
CGTCGAGGGCATGGATTGTCCAGACACGGGGCATGAGGGGCAGCGCCGCCCTGACGCCTGACGGACAGACCTACCAGCAG
CCCATCATTGCCGCGAGTGGGCCAGGGCGCGTGGGCCGTGGAGACGCCTTTGCGGGTGGCTTCTTGCATGCCTTTTTGCA
GGGAAAAGCGCCTCCCGCCGCCCTGGCTTTTGCGACCGCCGCCGCTGCCCTGAAAACCACGACACCTGGCGACCAGCTGC
AGGCAACCGAAGCCGAGGTATGGGCGGTACTGCAGGACGGCCAGGCCAGTGAACCGATCCGGTGA

Upstream 100 bases:

>100_bases
CTGGCGGTCGGTCTCGGCAGTCAGCTGTTCAAACTGAACGGAGACACACTGAAGGCCCAGCTGACGGACCTCTTGCGCTG
GACTCAGGCGGAAAGCAGCC

Downstream 100 bases:

>100_bases
CGGGCGCGACGCCAGGAGGAGAGAGATGGAATTGACCATGCGTTGGTTTGGTCCGGCAGACCCGGTAAAGCTCTGGCAGC
TGCGGCAGGTCCCGAACCTA

Product: PfkB

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAEAPTSVLTFGEALLKLVLLPTQRLESMQTLDAQCAGAELNVAAALAALGRPAAWVSALPAGPLGTWVRERVRALKVDD
LALTREGRLGTFYLEDHHPPRPSRVVYDRRGSAFTQLNAADFDPAWLAGRRALHVSGISLAVGQGPRDLALKLMWEARQA
GVVISFDVNHRRLLLAEDAARELYTPALRLADLIFVAERDTPLLGGLTGLRSLASRAWIVQTRGMRGSAALTPDGQTYQQ
PIIAASGPGRVGRGDAFAGGFLHAFLQGKAPPAALAFATAAAALKTTTPGDQLQATEAEVWAVLQDGQASEPIR

Sequences:

>Translated_314_residues
MAEAPTSVLTFGEALLKLVLLPTQRLESMQTLDAQCAGAELNVAAALAALGRPAAWVSALPAGPLGTWVRERVRALKVDD
LALTREGRLGTFYLEDHHPPRPSRVVYDRRGSAFTQLNAADFDPAWLAGRRALHVSGISLAVGQGPRDLALKLMWEARQA
GVVISFDVNHRRLLLAEDAARELYTPALRLADLIFVAERDTPLLGGLTGLRSLASRAWIVQTRGMRGSAALTPDGQTYQQ
PIIAASGPGRVGRGDAFAGGFLHAFLQGKAPPAALAFATAAAALKTTTPGDQLQATEAEVWAVLQDGQASEPIR
>Mature_313_residues
AEAPTSVLTFGEALLKLVLLPTQRLESMQTLDAQCAGAELNVAAALAALGRPAAWVSALPAGPLGTWVRERVRALKVDDL
ALTREGRLGTFYLEDHHPPRPSRVVYDRRGSAFTQLNAADFDPAWLAGRRALHVSGISLAVGQGPRDLALKLMWEARQAG
VVISFDVNHRRLLLAEDAARELYTPALRLADLIFVAERDTPLLGGLTGLRSLASRAWIVQTRGMRGSAALTPDGQTYQQP
IIAASGPGRVGRGDAFAGGFLHAFLQGKAPPAALAFATAAAALKTTTPGDQLQATEAEVWAVLQDGQASEPIR

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 33405; Mature: 33273

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAPTSVLTFGEALLKLVLLPTQRLESMQTLDAQCAGAELNVAAALAALGRPAAWVSAL
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHC
PAGPLGTWVRERVRALKVDDLALTREGRLGTFYLEDHHPPRPSRVVYDRRGSAFTQLNAA
CCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCEEEECCCCEEEECCCC
DFDPAWLAGRRALHVSGISLAVGQGPRDLALKLMWEARQAGVVISFDVNHRRLLLAEDAA
CCCHHHHHCCEEEEECCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHH
RELYTPALRLADLIFVAERDTPLLGGLTGLRSLASRAWIVQTRGMRGSAALTPDGQTYQQ
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEECCCCCHHHC
PIIAASGPGRVGRGDAFAGGFLHAFLQGKAPPAALAFATAAAALKTTTPGDQLQATEAEV
CEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHE
WAVLQDGQASEPIR
EEEEECCCCCCCCC
>Mature Secondary Structure 
AEAPTSVLTFGEALLKLVLLPTQRLESMQTLDAQCAGAELNVAAALAALGRPAAWVSAL
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHC
PAGPLGTWVRERVRALKVDDLALTREGRLGTFYLEDHHPPRPSRVVYDRRGSAFTQLNAA
CCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCEEEECCCCEEEECCCC
DFDPAWLAGRRALHVSGISLAVGQGPRDLALKLMWEARQAGVVISFDVNHRRLLLAEDAA
CCCHHHHHCCEEEEECCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHH
RELYTPALRLADLIFVAERDTPLLGGLTGLRSLASRAWIVQTRGMRGSAALTPDGQTYQQ
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEECCCCCHHHC
PIIAASGPGRVGRGDAFAGGFLHAFLQGKAPPAALAFATAAAALKTTTPGDQLQATEAEV
CEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHE
WAVLQDGQASEPIR
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA