Click here to switch to the map view.

The map label for this gene is cobM [H]

Identifier: 94971826

GI number: 94971826

Start: 132050

End: 132829

Strand: Direct

Name: cobM [H]

Synonym: Dgeo_2357

Alternate gene names: 94971826

Gene position: 132050-132829 (Clockwise)

Preceding gene: 94971827

Following gene: 94971825

Centisome position: 23.0

GC content: 70.26

Gene sequence:

>780_bases
GTGAAGGTGTATTTCATCGGCGCTGGTCCTGGCGCCCCCGACCTCATCACCGTGCGGGGGGCGCGGCTGCTGGCGCAGGC
GGACCTCATTCTCTACGCTGGGTCGCTGGTGCCGGAGGCCGTGCTCGAACACGCCCGCCCGCAGACGCCCCGGTATGACA
CCGCCCGGCTCCATCTGGCCGAGCAGCGCGAGCTGTACGCGCGGGCACGGCGGGAAGGTCTGACGGTGGCTCGCGTCCAC
TCCGGCGACCCCGCCCTCTACGGCGCGACCGCAGAACAGATGCAGCTGCTGCGCGAGCTGGATATCCCCTACGAGGTGGT
GCCCGGCGTGAGCAGCTTCACCGCCTGCGCCGCCACGCTGGGGGCCGAACTCACCCGTCCTCATGTCACCCAGACAGTCA
TTCTGACTCGGGCCTCGGGCCGCGCAAGTCCGGTGCCGGAGGCGGAAAACCTGGCGAGTCTGGCCGCCCACCGCGCCAGC
CTGTGCGTCTTTCTGGGCGGGCATCAACTGGAGCAGAACGTGGCGGCGCTCCTGACCCACTACCCGCCCGACACGCCCGC
TGCGCTGGTCCAGCGGGCCTCCCAGCCGGAGGAACGGCGGCACGTGGCAACTCTGGGCACGCTGCTGGATGGCCTGAAGC
TCAGCGAGTGGACGCTGACCACCCTGCTGCTCGTCAGCCCGGCGCTGGGGAGCGTGGAGGAACTGGAGACCTTCAGTCGT
CTCTATGACCCCGCCTACGCCCACCGCTTTCGCCGCGCGGAGAAGGGCGGTGAGGCGTGA

Upstream 100 bases:

>100_bases
CCGACTCCCCAATGGGTCGCCGGGAACGGCCTCCCCTCGACGGACGCCTGGGGTACCTGAGCGTGCTGCTGATTCGCCGG
CATCCGCCCCGGAGGTTTTT

Downstream 100 bases:

>100_bases
CGGCAGCCGGTGAGCTGGCGGTGTGGCCCGTGCGCCGCGACTCGGAGGCCCTGGCCGGGCGGTTGGCGCTGAGCTTGGAC
GCGGCCCTCTACCGGCCTTG

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKVYFIGAGPGAPDLITVRGARLLAQADLILYAGSLVPEAVLEHARPQTPRYDTARLHLAEQRELYARARREGLTVARVH
SGDPALYGATAEQMQLLRELDIPYEVVPGVSSFTACAATLGAELTRPHVTQTVILTRASGRASPVPEAENLASLAAHRAS
LCVFLGGHQLEQNVAALLTHYPPDTPAALVQRASQPEERRHVATLGTLLDGLKLSEWTLTTLLLVSPALGSVEELETFSR
LYDPAYAHRFRRAEKGGEA

Sequences:

>Translated_259_residues
MKVYFIGAGPGAPDLITVRGARLLAQADLILYAGSLVPEAVLEHARPQTPRYDTARLHLAEQRELYARARREGLTVARVH
SGDPALYGATAEQMQLLRELDIPYEVVPGVSSFTACAATLGAELTRPHVTQTVILTRASGRASPVPEAENLASLAAHRAS
LCVFLGGHQLEQNVAALLTHYPPDTPAALVQRASQPEERRHVATLGTLLDGLKLSEWTLTTLLLVSPALGSVEELETFSR
LYDPAYAHRFRRAEKGGEA
>Mature_259_residues
MKVYFIGAGPGAPDLITVRGARLLAQADLILYAGSLVPEAVLEHARPQTPRYDTARLHLAEQRELYARARREGLTVARVH
SGDPALYGATAEQMQLLRELDIPYEVVPGVSSFTACAATLGAELTRPHVTQTVILTRASGRASPVPEAENLASLAAHRAS
LCVFLGGHQLEQNVAALLTHYPPDTPAALVQRASQPEERRHVATLGTLLDGLKLSEWTLTTLLLVSPALGSVEELETFSR
LYDPAYAHRFRRAEKGGEA

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=246, Percent_Identity=27.6422764227642, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322922, Length=212, Percent_Identity=28.7735849056604, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 28027; Mature: 28027

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYFIGAGPGAPDLITVRGARLLAQADLILYAGSLVPEAVLEHARPQTPRYDTARLHLA
CEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
EQRELYARARREGLTVARVHSGDPALYGATAEQMQLLRELDIPYEVVPGVSSFTACAATL
HHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHH
GAELTRPHVTQTVILTRASGRASPVPEAENLASLAAHRASLCVFLGGHQLEQNVAALLTH
HHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHC
YPPDTPAALVQRASQPEERRHVATLGTLLDGLKLSEWTLTTLLLVSPALGSVEELETFSR
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LYDPAYAHRFRRAEKGGEA
HHCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVYFIGAGPGAPDLITVRGARLLAQADLILYAGSLVPEAVLEHARPQTPRYDTARLHLA
CEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
EQRELYARARREGLTVARVHSGDPALYGATAEQMQLLRELDIPYEVVPGVSSFTACAATL
HHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHH
GAELTRPHVTQTVILTRASGRASPVPEAENLASLAAHRASLCVFLGGHQLEQNVAALLTH
HHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHC
YPPDTPAALVQRASQPEERRHVATLGTLLDGLKLSEWTLTTLLLVSPALGSVEELETFSR
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LYDPAYAHRFRRAEKGGEA
HHCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]