| Definition | Cupriavidus metallidurans CH34 megaplasmid, complete sequence. |
|---|---|
| Accession | NC_007974 |
| Length | 2,580,084 |
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The map label for this gene is ilvX [H]
Identifier: 94312824
GI number: 94312824
Start: 440110
End: 441651
Strand: Direct
Name: ilvX [H]
Synonym: Rmet_3896
Alternate gene names: 94312824
Gene position: 440110-441651 (Clockwise)
Preceding gene: 94312823
Following gene: 94312828
Centisome position: 17.06
GC content: 67.64
Gene sequence:
>1542_bases ATGAACGGCGCGGAAAGCCTGGTGAAGACGCTGCTGGCTTGCGGCGTCGATACCTGCTTTGCCAACCCCGGCACCAGCGA AATGCATTTCGTGGCGGCGCTGGACCGGATTCCCGGCATGAAATGCGTGCTGGGCCTGTTCGAAGGCGTGGTCACTGGCG CGGCCGATGGCTACGCGCGCATGGCCGACAAGCCGGCCGCCACGCTGCTCCACTGCGGCCCGGGACTGGCCAACGGCCTG GCCAACCTGCACAACGCGCGCCGCGCGCAGACACCGATCATCAACATCATCGGTGATCAGGCCACCTATCATCGTCCGCT CGACGCGCCGCTGACCGCGGATACCGAAGGTTGGGCGCGCCCCGTTTCGGTCTGGACGCGTACCGCTACCCATGCGGCGT CGGTTGGTGCCGATGCCGCCGCGGCGGTGCAGGCCGCGACTTCCGCGCCGGGTGGCGTGGCAAGCCTGATCTTGCCATCG GATGTTTGCTGGGATGCGGGTGGCAAGGTGGCCGCGCCGCTGCCGGCGCTGGCCGTGCCGAAGGTGTCGCCCGATGCCGT GCAGAACGCCGCGCGCGTGCTGCGCAGCGGCCAGCCCACGCTGATCGTGCTGGCGGGCAACGCCTTGCGCACTGGCGCCC TGGCCGATGCGCACCGGATTGCCGCCGCCACCGATGCGCGGCTGATCACGCCGATGTCGAATTCGCGCGTGACGCGTGGA CGTGGCCATCTGGCTGTTGACCGTATTCCATACTCCGGTGACGTGGCACGCCAGAAGCTGGCGGGTATCCGCAATGTGAT CCTGGTCGGCGCGCCCGCACCGGTGACGTTCTTCGCCTATCCGGGCAAGTCGCCGCGTCCGTACCCCGAGGATGCTGTCA TCCACGTGCTGGCCCGGCCCGAAGAAGATCTGGGCGAGGCATTGGCCCGCCTGTCGGACGAATTGGGTGCGCGTAATGCT CCGCTGCCGGCCTCGGCCCATATCACTGCGGAGCCGGCAAAGGGTGCGGTGACATCCGAGGCGGTGGCGCAGACGCTGAC CGCGCTGTTGCCCGACCAGGCCGTAGTGGTGGAAGAGAGTGTGAGCTTCGGCCGCGCGTTCTATCCCGGCACGGTCCATG CCGCGCCACACGACTGGCTGCAACTGACCGGCGGCGCGATTGGCGCTGGCCTGCCGCTTGCCACGGGCGCTGCAATCGCG GCACCGGACCGCCGCGTGGTGGCGTTGCAGGCCGATGGATCGGGCATGTACACGCTGCAGTCGCTGTGGACCATGGCGCG TGAAAAGCTTGATGTGACCATCGTGCTGCTGGCCAATCGCAAGTACGCGATCCTGCTGGGCGAGCTGGCGGGTGTGGGTG CCAATCCCGGCAAGACCGCGCTGGATATGCTCGACCTCGGCAACCCGGATCTGGACTGGGTCAAGATGGCCAACGGTATG GGCGTGGAAGCTGCGCGTGCGGAGAACATGGAGACGTTCGCCGACCTGTTCCGCATGGCCAACCAGCGCAAGGGCCCGTT CCTGATCGAGCTGGTGATCTGA
Upstream 100 bases:
>100_bases GTTCCCGACCGAGTATGTCTGCCTGGATTTCGATCTGCTCGCCCCCCATTCCTGACAACACCCACCAAATACGGAACCTG CAATGGAGACTCAAGACACG
Downstream 100 bases:
>100_bases GGGGAATTCCTCGCAGATTGACGGCGCCCCTCTCCCGCTTGGCGGGAGAGGGTAGCGAACCTTCCTTCAACCTTCCACTT CCGCCCAGCCCGCCATTGCC
Product: hypothetical protein
Products: NA
Alternate protein names: ALS; Acetohydroxy-acid synthase large subunit; AHAS [H]
Number of amino acids: Translated: 513; Mature: 513
Protein sequence:
>513_residues MNGAESLVKTLLACGVDTCFANPGTSEMHFVAALDRIPGMKCVLGLFEGVVTGAADGYARMADKPAATLLHCGPGLANGL ANLHNARRAQTPIINIIGDQATYHRPLDAPLTADTEGWARPVSVWTRTATHAASVGADAAAAVQAATSAPGGVASLILPS DVCWDAGGKVAAPLPALAVPKVSPDAVQNAARVLRSGQPTLIVLAGNALRTGALADAHRIAAATDARLITPMSNSRVTRG RGHLAVDRIPYSGDVARQKLAGIRNVILVGAPAPVTFFAYPGKSPRPYPEDAVIHVLARPEEDLGEALARLSDELGARNA PLPASAHITAEPAKGAVTSEAVAQTLTALLPDQAVVVEESVSFGRAFYPGTVHAAPHDWLQLTGGAIGAGLPLATGAAIA APDRRVVALQADGSGMYTLQSLWTMAREKLDVTIVLLANRKYAILLGELAGVGANPGKTALDMLDLGNPDLDWVKMANGM GVEAARAENMETFADLFRMANQRKGPFLIELVI
Sequences:
>Translated_513_residues MNGAESLVKTLLACGVDTCFANPGTSEMHFVAALDRIPGMKCVLGLFEGVVTGAADGYARMADKPAATLLHCGPGLANGL ANLHNARRAQTPIINIIGDQATYHRPLDAPLTADTEGWARPVSVWTRTATHAASVGADAAAAVQAATSAPGGVASLILPS DVCWDAGGKVAAPLPALAVPKVSPDAVQNAARVLRSGQPTLIVLAGNALRTGALADAHRIAAATDARLITPMSNSRVTRG RGHLAVDRIPYSGDVARQKLAGIRNVILVGAPAPVTFFAYPGKSPRPYPEDAVIHVLARPEEDLGEALARLSDELGARNA PLPASAHITAEPAKGAVTSEAVAQTLTALLPDQAVVVEESVSFGRAFYPGTVHAAPHDWLQLTGGAIGAGLPLATGAAIA APDRRVVALQADGSGMYTLQSLWTMAREKLDVTIVLLANRKYAILLGELAGVGANPGKTALDMLDLGNPDLDWVKMANGM GVEAARAENMETFADLFRMANQRKGPFLIELVI >Mature_513_residues MNGAESLVKTLLACGVDTCFANPGTSEMHFVAALDRIPGMKCVLGLFEGVVTGAADGYARMADKPAATLLHCGPGLANGL ANLHNARRAQTPIINIIGDQATYHRPLDAPLTADTEGWARPVSVWTRTATHAASVGADAAAAVQAATSAPGGVASLILPS DVCWDAGGKVAAPLPALAVPKVSPDAVQNAARVLRSGQPTLIVLAGNALRTGALADAHRIAAATDARLITPMSNSRVTRG RGHLAVDRIPYSGDVARQKLAGIRNVILVGAPAPVTFFAYPGKSPRPYPEDAVIHVLARPEEDLGEALARLSDELGARNA PLPASAHITAEPAKGAVTSEAVAQTLTALLPDQAVVVEESVSFGRAFYPGTVHAAPHDWLQLTGGAIGAGLPLATGAAIA APDRRVVALQADGSGMYTLQSLWTMAREKLDVTIVLLANRKYAILLGELAGVGANPGKTALDMLDLGNPDLDWVKMANGM GVEAARAENMETFADLFRMANQRKGPFLIELVI
Specific function: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine [H]
COG id: COG0028
COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TPP enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1790104, Length=563, Percent_Identity=24.3339253996448, Blast_Score=87, Evalue=3e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012001 - InterPro: IPR011766 [H]
Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]
EC number: =2.2.1.6 [H]
Molecular weight: Translated: 53134; Mature: 53134
Theoretical pI: Translated: 6.74; Mature: 6.74
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGAESLVKTLLACGVDTCFANPGTSEMHFVAALDRIPGMKCVLGLFEGVVTGAADGYAR CCHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH MADKPAATLLHCGPGLANGLANLHNARRAQTPIINIIGDQATYHRPLDAPLTADTEGWAR HCCCCCHHEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC PVSVWTRTATHAASVGADAAAAVQAATSAPGGVASLILPSDVCWDAGGKVAAPLPALAVP HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCCCCCEECCCCCCCCC KVSPDAVQNAARVLRSGQPTLIVLAGNALRTGALADAHRIAAATDARLITPMSNSRVTRG CCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEECC RGHLAVDRIPYSGDVARQKLAGIRNVILVGAPAPVTFFAYPGKSPRPYPEDAVIHVLARP CCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCC EEDLGEALARLSDELGARNAPLPASAHITAEPAKGAVTSEAVAQTLTALLPDQAVVVEES CHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECH VSFGRAFYPGTVHAAPHDWLQLTGGAIGAGLPLATGAAIAAPDRRVVALQADGSGMYTLQ HCCCCEECCCEECCCCCHHHHCCCCCCCCCCCHHCCCEEECCCCEEEEEEECCCCCHHHH SLWTMAREKLDVTIVLLANRKYAILLGELAGVGANPGKTALDMLDLGNPDLDWVKMANGM HHHHHHHHCCCEEEEEEECCCEEEEEECHHCCCCCCCCHHHHHHHCCCCCHHHHHHCCCC GVEAARAENMETFADLFRMANQRKGPFLIELVI CCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEC >Mature Secondary Structure MNGAESLVKTLLACGVDTCFANPGTSEMHFVAALDRIPGMKCVLGLFEGVVTGAADGYAR CCHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH MADKPAATLLHCGPGLANGLANLHNARRAQTPIINIIGDQATYHRPLDAPLTADTEGWAR HCCCCCHHEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC PVSVWTRTATHAASVGADAAAAVQAATSAPGGVASLILPSDVCWDAGGKVAAPLPALAVP HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCCCCCEECCCCCCCCC KVSPDAVQNAARVLRSGQPTLIVLAGNALRTGALADAHRIAAATDARLITPMSNSRVTRG CCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEECC RGHLAVDRIPYSGDVARQKLAGIRNVILVGAPAPVTFFAYPGKSPRPYPEDAVIHVLARP CCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCC EEDLGEALARLSDELGARNAPLPASAHITAEPAKGAVTSEAVAQTLTALLPDQAVVVEES CHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECH VSFGRAFYPGTVHAAPHDWLQLTGGAIGAGLPLATGAAIAAPDRRVVALQADGSGMYTLQ HCCCCEECCCEECCCCCHHHHCCCCCCCCCCCHHCCCEEECCCCEEEEEEECCCCCHHHH SLWTMAREKLDVTIVLLANRKYAILLGELAGVGANPGKTALDMLDLGNPDLDWVKMANGM HHHHHHHHCCCEEEEEEECCCEEEEEECHHCCCCCCCCHHHHHHHCCCCCHHHHHHCCCC GVEAARAENMETFADLFRMANQRKGPFLIELVI CCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]