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The map label for this gene is marR [H]

Identifier: 94312812

GI number: 94312812

Start: 428646

End: 429179

Strand: Direct

Name: marR [H]

Synonym: Rmet_3884

Alternate gene names: 94312812

Gene position: 428646-429179 (Clockwise)

Preceding gene: 94312811

Following gene: 94312817

Centisome position: 16.61

GC content: 60.3

Gene sequence:

>534_bases
ATGGATGAGGCCGGTACCCGCCAAAAGGCTTTTCTCGACCTGGCGCATCAGATACATTGGCGTTTCACGAACGGGTCAGG
GTGCCGCGAAGCCGTGAAACACTACTCCTCCGAAAACTTCCACCTCACGCAAAGCATCGGATTCCATCTCAACCGGGCAC
GCAACATCCTGTTGATGGAGATGGATGCCGCACTGCGGCCACTCGACATCACGGGCCAGCAGATGGGCATCCTGCTGTCG
CTGACGCGCGGCGTGGCCACCACGCCGTTTGAGATCAGCAAGGTGCTTGGGATCGATACCGGCCTGATGACGCGGATGCT
CGACAAGCTCGAGAGCCGCGGATTGCTACAGCGCCAGCGTAGCATCGAGGACCGGCGGGTGATTCATCTGCTCCTGACGG
ACAAGGGCAGGGAAGTGGCGACCCGCATTCCCGAGATCGCGCCCGAAGTGCTCAACCATCGGCTGCGCGATTTCTCCACG
GAGGAATTCTGCGAGTTCCTGCGGCTGCTGCGCAAATTCACCGATTCCGACTAG

Upstream 100 bases:

>100_bases
CGGATAGTGCGGTGACTCTTGGGAAGCAGGAGGGGAGACAGGGGGAGACAGGGCTGCCAGGGCAATCCCGCCAGCTCTGC
CCGATTTCTGCTTTCACGCA

Downstream 100 bases:

>100_bases
GCCGGACCCGCGAATCGCTGGGGTGAGCGGCGGATGCCGCTTCCCCCTTCCCGCGAGCGGCGGCTTAATCGAGCAGGCGC
GACAACGCAGGCGGCAGCCC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MDEAGTRQKAFLDLAHQIHWRFTNGSGCREAVKHYSSENFHLTQSIGFHLNRARNILLMEMDAALRPLDITGQQMGILLS
LTRGVATTPFEISKVLGIDTGLMTRMLDKLESRGLLQRQRSIEDRRVIHLLLTDKGREVATRIPEIAPEVLNHRLRDFST
EEFCEFLRLLRKFTDSD

Sequences:

>Translated_177_residues
MDEAGTRQKAFLDLAHQIHWRFTNGSGCREAVKHYSSENFHLTQSIGFHLNRARNILLMEMDAALRPLDITGQQMGILLS
LTRGVATTPFEISKVLGIDTGLMTRMLDKLESRGLLQRQRSIEDRRVIHLLLTDKGREVATRIPEIAPEVLNHRLRDFST
EEFCEFLRLLRKFTDSD
>Mature_177_residues
MDEAGTRQKAFLDLAHQIHWRFTNGSGCREAVKHYSSENFHLTQSIGFHLNRARNILLMEMDAALRPLDITGQQMGILLS
LTRGVATTPFEISKVLGIDTGLMTRMLDKLESRGLLQRQRSIEDRRVIHLLLTDKGREVATRIPEIAPEVLNHRLRDFST
EEFCEFLRLLRKFTDSD

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=125, Percent_Identity=32, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 20375; Mature: 20375

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEAGTRQKAFLDLAHQIHWRFTNGSGCREAVKHYSSENFHLTQSIGFHLNRARNILLME
CCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCEEEEE
MDAALRPLDITGQQMGILLSLTRGVATTPFEISKVLGIDTGLMTRMLDKLESRGLLQRQR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
SIEDRRVIHLLLTDKGREVATRIPEIAPEVLNHRLRDFSTEEFCEFLRLLRKFTDSD
CCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDEAGTRQKAFLDLAHQIHWRFTNGSGCREAVKHYSSENFHLTQSIGFHLNRARNILLME
CCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCEEEEE
MDAALRPLDITGQQMGILLSLTRGVATTPFEISKVLGIDTGLMTRMLDKLESRGLLQRQR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
SIEDRRVIHLLLTDKGREVATRIPEIAPEVLNHRLRDFSTEEFCEFLRLLRKFTDSD
CCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]